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核开关三维结构与机理 X-ray晶体结构、RNA调节因子发现、功能和机理。
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1、Ding F, Lu Changrui et al. Structure and assembly of the essential RNA ring component of a viral DNA packaging motor. PNAS. 2011
Lu Changrui, Ding F, Ke A. Folding of the SAM-III/SMK box riboswitch is hypersensitive to sequences outside the SAM-binding core. Journal of Molecular Biology. 2011
2、Lu Changrui, et al. SAM Recognition and Conformational Switching Mechanism in the Bacillus subtilis yitJ S Box/SAM-I Riboswitch. Journal of Molecular Biology. 2010
3、Lu Changrui, Ding F, Ke A. Crystal structure of the S. solfataricus archaeal exosome reveals conformational flexibility in the RNA-binding ring. PLoS ONE. 2010
4、Lu Changrui. et al. Crystal Structures of the SMK box (SAM-III) Riboswitch Reveal the SAM-dependent Translation Inhibition Mechanism. Nature SMB. 2008
5、Pruitt NL, Changrui Lu. Seasonal changes in phospholipid class and class-specific fatty acid composition associated with the onset of freeze tolerance in third-instar larvae of Eurosta solidaginis. Physiological and biochemical zoology. 2008
6、Perreira M, Jiang JK, Klutz AM, Gao ZG, Shainberg A, Changrui Lu, Thomas CJ, Jacobson KA. “Reversine” and its 2-substituted adenine derivatives as potent and selective A3 adenosine receptor antagonists. Journal of medicinal chemistry. 2005
7、Jeong LS, Lee HW, Jacobson KA, Kim HO, Shin DH, Lee JA, Gao ZG, Changrui Lu, Duong HT, Gunaga P, Lee SK, Jin DZ, Chun MW, Moon HR. Structure-activity relationships of 2-chloro-N6-substituted-4‘-thioadenosine-5’-uronamides as highly potent and selective agonists at the human A3 adenosine receptor. J Med Chem. 2006
8、Cosyn L, Gao ZG, Van Rompaey P, Changrui Lu, Jacobson KA, Van Calenbergh S. Synthesis of hypermodified adenosine derivatives as selective adenosine A3 receptor ligands. Bioorg Med Chem. 2006
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