陈世桢 - 中国科学院精密测量科学与技术创新研究院 -

个人简介

学习经历 2000.9-2004.6华中师范大学化学（本科） 2005.9-2011.6华中师范大学分析化学（博士）工作经历 2011.9-2013.9中国科学院武汉物理与数学所博士后 2013.10-2018.10中国科学院武汉物理与数学所副研究员 2018.10-至今中国科学院精密测量科学与技术创新研究院研究员/博导陈世桢，女，博士，研究员，博导。从事磁共振分子影像及肿瘤的多模态影像研究，主要影像手段包括MRI、 CT、 PET、超声、光声和光学成像等。承担多项国家自然科学基金项目及中科院前沿科学重点研究计划和中科院科研仪器研制项目各一项。在Nano. Lett，ACS Nano，Angew. Chemie等国际知名期刊上发表SCI 论文30余篇，总引超过1200次。申请15项发明专利，授权8项。2017年获中国分析测试协会科技奖（第一完成人），2018年入选中国科学院青年创新促进会。获奖及荣誉 2014年入选武昌英才计划 2017年获中国分析测试协会科技奖（第一完成人） 2018年入选中科院青促会 2020年荣获“湖北省百名优秀女性科技创新人才”称号 2021湖北省博士后卓越人才计划 2021湖北省杰出青年科学基金 2021湖北省青年拔尖人才 2021年荣获武汉"新时代巾帼英雄"

研究领域

19F/129Xe/1H磁共振分子影像及肿瘤的多模态影像研究

近期论文

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Shizhen Chen , Yina Lan, Haidong Li, Liming Xia, Chaohui Ye, Xin Lou*, Xin Zhou*. Relationship between Lung and Brain Injury in COVID-19 Patients: A Hyperpolarized 129Xe-MRI-based 8-Month Follow-Up. Biomedicines, Vol 10(4), 781-789. (2022) Sha Li, Weiping Jiang, Yaping Yuan, Meiju Sui, Yuqi Yang, Liqun Huang, Ling Jiang, Maili Liu, Shizhen Chen*, Xin Zhou*. Delicately Designed Cancer Cell Membrane-Camouflaged Nanoparticles for Targeted 19F MR/PA/FL Imaging-Guided Photothermal Therapy. ACS Applied Materials & Interfaces, Vol 12(51), 57290-57301. (2020). Lili Ren , Shizhen Chen *, Weiping Jiang, Qingbin Zeng, Xu Zhang, Long Xiao, Michael T. McMahon, Xin Lou, Xin Zhou*. Efficient Temperature-feedback Liposome for 19F MRI Signal Enhancement. Chemical Communication, Vol 56(92), 14427-14430. (2020). Huaibin Zhang, Shaowei Bo, Kai Zeng, Jie Wang, Yu Li, Zhigang Yang, Xin Zhou*, Shizhen Chen*, Zhongxing Jiang*. Fluorinated Porphyrin-Based Theranostics for Dual Imaging and Chemo-Photodynamic Therapy. Journal of Materials Chemistry B, Vol 8(20), 4469-4474. (2020). Huaibin Zhang, Qiao Yu, Yu Li, Zhigang Yang, Xin Zhou, Shizhen Chen*, Zhongxing Jiang*. Fluorinated Cryptophane-A and Porphyrin-based Theranostics for Multimodal Imaging-guided Photodynamic Therapy. Chemical Communication, Vol 56(25), 3617-3620. (2020). Lianhua Liu, Yaping Yuan, Yuqi Yang, Michael McMahon, Shizhen Chen*, Xin Zhou*. A Fluorinated Aza-BODIPY Derivative for NIR fluorescence/PA/19F MR Tri-modality In Vivo Imaging. Chemical Communications, Vol 55(42), 5851-5854. (2019). Huaibin Zhang , Shizhen Chen , Yaping Yuan, Yu Li, Zhongxing Jiang*, Xin Zhou*. Xe Hyper-CEST/ F MRI Multimodal Imaging System for Sensitive and Selective Tumor Cells Detection. ACS Applied Bio Materials, Vol 2(1), 27-32. (2019). Yuqi Yang , Shizhen Chen , Haidong Li, Yaping Yuan, Zhiying Zhang, Junshuai Xie, Dennis.W Hwang, Aidong Zhang, Maili Liu, Xin Zhou*. Engineered Paramagnetic Graphene Quantum Dots with Enhanced Relaxivity for Tumor Imaging. Nano Letters, Vol 19(1), 441-448. (2019). Sha Li, Yaping Yuan, Yuqi Yang, Conggang Li, Michael T. McMahon, Maili Liu, Shizhen Chen*, Xin Zhou*. Potential Detection of Cancer with Fluorinated Silicon Nanoparticles in 19F MR and Fluorescence Imaging. Journal of Materials Chemistry B, Vol 6, 4293-4300. (2018). Xi Huang, Yaping Yuan, Weiwei Ruan, Lianhua Liu, Maili Liu, Shizhen Chen*, Xin Zhou*. pH-responsive Theranostic Nanocomposites as Synergistically Enhancing Positive and Negative Magnetic Resonance Imaging Contrast Agents. Journal of Nanobiotechnology, Vol 16(30). (2018)