张波 - 中国科学院武汉病毒研究所 -

个人简介

张波，博士，学科组长研究员，新发传染病研究中心副主任。1998年、2001年于山东大学微生物系分别获得学士及硕士学位，2005年于德国吕贝克大学医学分子生物学系获博士学位。2006至2009年于美国纽约州立卫生署Wadsworth Center从事博士后研究。

研究领域

主要研究方向为黄病毒和甲病毒复制机制、新型疫苗研发、抗病毒药物筛选等研究。

近期论文

查看导师新发文章（温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

Different pathogenesis of SARS-CoV-2 Omicron variant in wild-type laboratory mice and hamsters. Zhang YN, Zhang ZR, Zhang HQ, Li N, Zhang QY, Li XD, Deng CL, Deng F, Shen S, Zhu B, Zhang B. Signal Transduct Target Ther. 2022 Feb 25;7(1):62. doi: 10.1038/s41392-022-00930-2. High titer self-propagating capsidless Chikungunya virus generated in Vero cells as a strategy for alphavirus vaccine development. Zhang YN, Zhang ZR, Li N, Pei XR, LiXD, Deng CL, Ye HQ*, Zhang B*. J Virol. 2022 Feb 2:JVI0148021. doi: 10.1128/JVI.01480-21. Online ahead of print. Intranasal delivery of replicating mRNA encoding neutralizing antibody against SARS-CoV-2 infection in mice. Li JQ#, Zhang ZR#, Zhang HQ#, Zhang YN#, Zeng XY, Zhang QY, Deng CL, Li XD*, Zhang B*, Ye HQ*. Signal Transduct Target Ther. 2021 Oct 25;6(1):369. Increased morbidity of obese mice infected with mouse-adapted SARS-CoV-2. Zhang YN#, Zhang ZR#, Zhang HQ#, Li XD, Li JQ, Zhang QY, Liu J, Li Q, Deng CL, Shi ZL, Yuan ZM, Ye HQ*, Zhang B*. Cell Discov. 2021 Aug 25;7(1):74. Rational design of West Nile virus vaccine through large replacement of 3' UTR withinternal poly(A). Zhang YN#, Li N#, Zhang QY#, Liu J, Zhan SL, Gao L, Zeng XY,Yu F, Zhang HQ, Li XD, Deng CL, Shi PY, Yuan ZM, Yuan SP, Ye HQ*, Zhang B*. EMBO Mol Med. 2021 Sep 7;13(9):e14108. A cell-based large-scale screening of natural compounds for inhibitors of SARS-CoV-2.Zhang ZR#, Zhang YN#, Li XD#, Zhang HQ, Xiao SQ, Deng F, Yuan ZM, Ye HQ*, Zhang B*. Signal Transduct Target Ther. 2020 Oct 3;5(1):218. A mouse model for SARS-CoV-2 infection by exogenous delivery of hACE2 using alphavirus replicon particles. Zhang YN#, Li XD#, Zhang ZR#, Zhang HQ, Li N, Liu J, Li JQ, Zhang HJ, Wang ZJ,Shen S, Shi ZL, Wei HP, Yuan ZM, Ye HQ*, Zhang B*. Cell Res. 2020 Nov;30(11):1046-1048. A novel rabies vaccine based on infectious propagating particles derived from hybrid VEEV-Rabies replicon. Ya-Nan Zhang#, Chen Chen#, Cheng-Lin Deng, Cheng-Guang Zhang, Na Li, Zhen Wang, Ling Zhao*, Bo Zhang*. EBioMedicine. 2020 Jun;56:102819. Short direct repeats in the 3'-untranslated region are involved in subgenomic flaviviral RNA production. Zhang QY, Li XF, Niu X, Li N, Wang HJ, Deng CL, Ye HQ, Huang XY, Chen Q, Xu YP, Dong HL, Li XD, Zhao H, Shi PY, Yuan ZM, Gong P, Fang X, Qin CF*, Zhang B*. J Virol. 2020 Feb 28;94(6). Different Degrees of 5'-3' DAR Interactions Modulate Zika Virus Genome Cyclization and Host SpecificReplication. Li XD, Deng CL, Yuan ZM, Ye HQ, Zhang B*. J Virol. 2020 Feb 14;94(5). Visualization of chikungunya virus infection in vitro and in vivo. Hong-Lei Zhang#, Hao-Long Dong#, Ya-Nan Zhang, Lin-Lin Xu, Cheng-Lin Deng, Xiao-Feng Li, Xiao-Dan Li, Han-Qing Ye, Zhi-Ming Yuan, Cheng-Feng Qin* & Bo Zhang*. Emerg Microbes Infect. 2019;8(1):1574-1583.