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个人简介

2009年-至今,南京林业大学,理学院化学与材料科学系,讲师、副教授、教授 2011-2018年,南京林业大学,现代分析测试中心,副主任 2007-2009年,美国德克萨斯大学(University of Texas,USA), 纳米药物研究所,博士后 2006-2007年,东南大学,生物医学工程学院,博士后 2006年,南京大学,无机化学,博士

研究领域

(1) PSiNPs荧光调控及其在胞内离子检测中的应用。 (2)“隐形”PSiNPs纳米载体的制备及其在药物递送中的应用。 (3) 近红外荧光PSiNPs探针在活体成像和药物递送中的应用 (4) 光热型PSiNPs纳米复合物在癌症组合治疗中的应用 (5) 可注射降解型PSiNPs纳米复合水凝胶在癌症局域治疗中的应用 (6) 磁性PSiNPs纳米复合物在肿瘤多模态成像和组合治疗中的应用 (7)亚细胞结构靶向载体的构筑及其在肿瘤治疗中的应用。 (8)肿瘤细胞膜包覆PSiNPs纳米复合物在肿瘤免疫治疗中的应用

近期论文

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Jiacheng. Li, Di. Huang, Ruoyu. Chen, Patrícia. Figueriredo, Flavia. Fontana, Alexandra. Correia, Shiqi. Wang, Zehua. Liu, Marianna. Kemell, Giulia. Torrieri, Ermei Makila, Jarno Salonen, Jouni Hirvonen, Yan. Gao, Jialiang. Li, Zhenyang. Luo*, Helder A. Santos*, and Bing Xia*, Multifunctional biomimetic nanovaccines based on photothermal and weak-immunostimulatory nanoparticulate cores for the immunotherapy of solid tumors, Adv. Mater., 2022, 34: 2108012. Ruoyu Cheng, Shiqi Wang*, Karina Moslova, Ermei Makila, Jarno Salonen, Jiachen Li, Jouni Hirvonen, Bing Xia, and Helder A. Santos*, Quantitative analysis of porous silicon nanoparticles functionalization by 1H NMR, ACS Biomater. Sci. Eng., 2021, DOI: 10.1021/acsbiomaterials.1c00440. Yan Gao, Haibei Tong, Jialiang Li, Jiachen Li, Di Huang, Jisen Shi*, and Bing Xia*, Mitochondria-targeted nanomedicine for enhanced efficacy of cancer therapy, Front. Bioeng. Biotech., 2021, 9: 720508. Bing Xia, Yan Gao, Jiachen Li, Near-infrared imaging for in vivo assessment of porous silcion based materials, Porous Silicon for Biomedical Application (2nd Edition), Charpter 10, Elsvier, 2021. Haibei Tong, Yan Gao, Di Huang, Jiachen Li, Jialiang Li, Jisen, Shi*, Helder Santos*, Bing Xia*, Mitochondria-targeted bovine serum albumin@copper sulfide nanocomposites conjugated with rhodamine-110 dyes for enhanced photothermal therapeutic efficacy, Particle & Particle Systems Characterization, 2021, 38, 202100013. Shiqi Wang, Saowanee Wannasarit, Patricia Figueriredo, Jiachen Li, Alexandra Correia, Bing Xia, Ruedeekorn Wiwattananpatapee, Jouni Hirvonen, Dongfei Liu, Wei Li*, Helder Santos*, Superfast and controllable microfluidic inking of anti-inflammatory melanin-like nanoparticles inspired by Cephalopd, Materials Horizons, 2020, 7, 1573-1580. Jiachen Li, Yan Gao, Haibei Tong,Weiwei Zhang, Jisen Shi*, Helder Santos*, Bing Xia*, Near infrared light and magnetic field dual-responsive porous silicon-based nanocarriers to ovecome multi-drug resistance of breast cancer cells with enhanced efficiency, Journal of Materials Chemistry B, 2020, 8, 546-557. Bing Xia*, Weiwei Zhang, Haibei Tong, Zhenyu Chen, Jiachen Li, and Jisen Shi, Multifunctionalchitosan/porous silicon@Au nanocomposite hydrogels for long-term and repeatedly localized combinatorial therapy of cancer via a single injection, ACS Biomaterials Science & Engineering, 2019, 51, 1857-1867. Bing Xia*, Weiwei Zhang, Jisen Shi, Zhenyu Chen, Qi Zhang, and Jiachen Li, NIR light-triggered gelling in situ of multifunctional porous silicon/PEGDA nanocomposites hydrogels for triple-combination therapy of cancer cells in vitro, Journal of Applied Polymer Science, 2019, 136, 47443. Bing Xia*, Qi Zhang, Jisen Shi, Jiachen Li, Zhenyu Chen, and Bin Wang, Co-loading of near-infrared dyes and anticancer drugs into porous silicon nanoparticles with enhanced chemo-photothermal therapeutic efficacy to kill multidrug-resistant cancer cells in vitro, Colloids and Surfaces B, 2018, 51, 197-208. Bing Xia*, Jiachen Li, Jisen Shi, Yu Zhang, Qi Zhang, Zhenyu Chen, and Bin Wang, Biodegradable and magnetic-fluorescent porous silicon@iron oxide nanocomposites for fluorescence/magnetic resonance bimodal imaging of tumor in vitro, ACS Biomaterials Science & Engineering, 2017, 3, 2579-2587(热点文章). Bing Xia*, Bin Wang, Jisen Shi, Yu Zhang, Zhenyu Chen, Qi Zhang, and Jiachen Li, Photothermal and biodegradable polyaniline/porous silicon hybrid nanocomposites as a multifunctional drug carrier for chemo-photothermal combination cancer therapy, Acta Biomaterialia, 2017, 51, 197-208. Bing Xia*, Bin Wang, Zhenyu Chen, Qi Zhang, Jisen Shi, Near-infrared light-triggered intracellular delivery of anticancer drugs using porous silicon nanoparticles conjugated with IR820 dyes, Advanced Materials Interfaces, 2016, 3, 1500715 (封面文章). Bing Xia*, Bin Wang, Wenyi Zhang, Jisen Shi, High loading of doxorubicin into styrene-terminated porous silicon nanoparticles via p-stacking for cancer treatments in vitro, RSC Advances, 2015, 5, 44660-44665. Bing Xia*, Bin Wang, Wenyi Zhang, Jisen Shi, and Shou-jun Xiao, Engineering near-infrared fluorescent styrene-terminated porous silicon nanocomposites with bovine serum albumin encapsulation for in vivo imaging, Journal of Materials Chemistry B, 2014, 2, 8314-8320. Bing Xia*, Wenyi Zhang, Jisen Shi, and Shou-jun Xiao, A novel strategy to fabricate doxorubicin/bovine serum albumin/porous silicon nanocomposites with pH-triggered drug delivery for cancer therapy in vitro, Journal of Materials Chemistry B, 2014, 2, 5280-5286. Bing Xia*, Jisen Shi, Wenyi Zhang, Chen Dong, Ye Lu, and Ping Guo, Covalent assembly of poly(ethyleneimine) via layer-by-layer deposition for enhancing surface density of protein and bacteria attachment, Applied Surface Science, 2014, 292, 1040-1044. Bing Xia*, Wenyi Zhang, Jisen Shi, and Shou-jun Xiao, Engineered stealth porous silicon nanoparticles via surface encapsulation of bovine serum albumin for prolonging their blood circulation in vivo, ACS Applied Materials & Interfaces, 2013, 5, 11718-11824. Bing Xia*, Wenyi Zhang, Jisen Shi, and Shou-jun Xiao, Fluorescence quenching in luminescent porous silicon nanoparticles for the detection of intracellular Cu2+, Analyst, 2013, 138, 3628-3632. Bing Xia*, Chen Dong, Wenyi Zhang, Ye Lu, Jinhui Chen, and Jisen Shi*, Highly efficient uptake of ultrafine mesoporous silica nanoparticles with excellent biocompatibility by Liriodendron hybrid suspension cells, SCIENCE CHINA Life Sciences, 2013, 56, 82-89.

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