研究领域

1.食用植物中的活性分子对阿尔茨海默病病人病症的缓解和治疗作用研究； 2.功能性食用胶体研究； 3.现代分析方法在食品分子营养领域的应用研究。

主持科研项目： 1、国家自然科学基金青年项目，81501619、小鼠脑内不同Ab聚集物的分型成像和靶向给药研究、2016/01-2018/12 2、湖南省自然科学基金青年项目，2015JJ3177、具有抗AD功效的米糠多酚的筛选及其对神经细胞的保护作用研究、2015/01-2017/12 3、湖南省教育厅科学研究项目,14C1184、水稻谷壳中黄酮类化合物通过干预Aβ自聚集抑制Aβ诱导的神经元凋亡的机理研究、2014/09-2016-09 4、长沙市科技计划项目，k1501003-31表面等离子体共振技术筛选具有抗阿尔茨海默病功能的黄酮类化合物及其成果产业化2014.6-2016.6

近期论文

查看导师最新文章 （温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

(1)TaoYang,FangZhu,TianxiaoZhou,JianzhongCao,MeiyiZhang,Dong-ShengCao,QinluLin,LinZhang*,Label-Free,Water-SolubleFluorescentPeptideProbeforSensitiveandSelectiveDeterminationofCopperIons,AnalyticalSciences,33:191-196,2017 (2)LinZhang,YuanqiangHao,XiaoyingWang,YunfeiLong,AngelaRamos,DianluJiang,XiaohuaMa,QinluLinandFeimengZhou*,Opticallytransparentelectrodesmodifiedwithsulfideion-coveredCdSquantumdotsforsensitivephotoelectrochemicaldetectionofsulfhydryl-containingcompounds,Electroanalysis,27,(8):1899-1905,2015 (3).LinZhang,GargeyYagnik,YongPeng,JianxiuWang,H.HowardXu,YuanqiangHao,You-NianLiu,andFeimengZhou*,Kineticstudiesofinhibitionoftheamyloidbeta(1–42)aggregationusingaferrocene-taggedβ-sheetbreakerpeptide,AnalyticalBiochemistry,434(2):292-299,2013 (4).LinZhang,TianhanKai,ZhifangSun,YuanqiangHao,QiuyunTu,andFeimengZhou*,Aferrocene-taggedamyloid-βfragmentforrapidscreeningofaggregationinhibitorsfromnaturalcompoundsbyHPLC-electrochemicaldetection,Electroanalysis,25(7):1659-1664,2013 (5).LinZhang,GargeyYagnik,DianluJiang,ShuyunShi,PeterChang,andFeimengZhou*,Separationofintermediatesofiron-catalyzeddopamineoxidationreactionsusingreversed-phaseion-pairingchromatographycoupledintandemwithUV–visibleandESI-MSdetections,JournalofChromatographyB,911,55-58,2012 (6).DianluJiang,LinZhang（并列第一作者）,GianPaolaG.Grant,ChristopherG.Dudzik,ShuChen,SvetiPatel,YuanqiangHao,GlennL.Millhauser,andFeimengZhou*,Theelevatedcopperbindingstrengthofamyloid-βaggregatesallowsthesequestrationofcopperfromalbumin:apathwaytoaccumulationofcopperinsenileplaques,Biochemistry,52(3):547-556,2013 (7)张琳，林亲录，阳明辉，β-淀粉样多肽自聚集抑制剂的电化学筛选方法研究，化学传感器，33(4):23-28,2013 (8)周天啸，刘馥歌，杨涛，张琳*，自组装多肽水凝胶包埋大蒜精油的控释研究，粮食与油脂，29:14-18,2016 (9)张琳，周天啸，王奔，郝雅晏，陆俊*，Fmoc-F多肽水凝胶对丁香精油的控释作用研究，食品与机械，32,8-11,2016 (10)张琳，肖华西，丁玉琴，林亲录，研讨式教学在食品科学类专业课程中的应用研究，教育教学论坛，2：155-156，2018 (11).TianhanKai,LinZhang，XiaoyingWang,AihuaJing,BingqingZhao,XiangYu,JieZheng,FeimengZhou,TabersonineinhibitsamyloidfibrilformationandcytotoxicityofAβ(1–42),ACSChemicalNeuroscience,6:879-884,2015 (12).ShuChen,LinZhang,YunfeiLong,andFeimengZhou*,Electroanalyticalsensorsandmethodsforassaysandstudiesofneurologicalbiomarkers,Electroanalysis,26(6):1236–1248,2014. (13).JieDong,Zhi‑JiangYao,LinZhang,FeijunLuo,QinluLin,Ai‑PingLu,AlexF.ChenandDong‑ShengCao1*,PyBioMed:apythonlibraryforvariousmolecularrepresentationsofchemicals,proteinsandDNAsandtheirinteractions,JournalofCheminformatics,10(16):,2018 (14).DianluJiang,ShuyunShi,LinZhang,LinLiu,BingrongDing,BingqingZhao,GargeyYagnik,andFeimengZhou*,InhibitionoftheFe(III)-catalyzeddopamineoxidationbyATPanditsrelevancetooxidativestressinParkinson’sDisease,ACSChemicalNeuroscience,4(9):1305-1313,2013 (15).Chuan-WanWei,YongPeng,LinZhang,QiyuHuang,MingCheng,You-NianLiu*,JuanLi,Synthesisandevaluationofferrocenoylpentapeptide(Fc-KLVFF)asaninhibitorofAlzheimer’sAb(1–42)fibrilformationinvitro,Bioorganic&medicinalchemistryletters,21(19):5818-5821,2011 (16).ChengshanWang,LinLiu,LinZhang,YongPeng,andFeimengZhou*,Redoxreactionsofthea-synuclein-Cu2+complexandtheireffectsonneuronalcellviability,Biochemistry,49(37):8134–8142,2010 (17).Yin-HuaDeng,Ning-ningWang,Zhen-xingZou,LinZhang,Kang-PingXu,AlexF.Chen,Dong-ShengCao*,andGui-ShanTan*,Multi-targetscreeningandexperimentalvalidationofnaturalproductsfromselaginellaplantsagainstAlzheimer’sDisease,FrontiersinPharmacology,8,article539,2017 (18).YongPeng,DianluJiang,LeiSu,LinZhang,MingYan,JuanjuanDu,YufengLu,You-NianLiu,andFeimengZhou*.Mixedmonolayersofferrocenylalkanethiolandencapsulatedhorseradishperoxidaseforsensitiveanddurableelectrochemicaldetectionofhydrogenperoxide.AnalyticalChemistry,81(24):9985–9992,2009 (19).Ling-BinOu,You-NianLiu*,JianxiuWang,andLinZhang,Enhancedvoltammetricdetectionofepinephrineatacarbonnanotube/nafioncompositeelectrodeinthepresenceofascorbicacid,JournalofNanoscienceandNanotechnology,9(11):6614-6619,2009 (20)TaoYang,HuifenHuang,FangZhu,QinluLin,LinZhang,andJunwenLiu,Recentprogressesinnanobiosensingforfoodsafetyanalysis,Sensors,16,1118,2016 (21)HuaxiXiao,TaoYang,QinluLin,Gao-qiangLiu,LinZhang,FengxiangYu,andYuejiaoChen,Acetylatedstarchnanocrystals:preparationandantitumordrugdeliverystudy,Internationaljournalofbiologicalmacromolecules,89:456-464,2016