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"[2,3]-Sigmatropic Rearrangements of 2-Phosphineborane 2-Propen-1-ols: Rapid Access to Enantioenriched Diphosphine Monoxide Derivatives," Busacca, C. A.; Qu, B.; Farber, E.; Haddad, N.; Gret, N.; Saha, A. K.; Eriksson, M. C.; Wu, J.-P.; Fandrick, K. R.; Han, S.; Grinberg, N.; Ma, S.; Lee, H.; Li, Z.; Spinelli, M.; Gold, A.; Wang, Z.; Wang, G.; Wipf, P.; Senanayake, C.H., Org. Lett., Vol. 15, 2013, Pages (5),1136-1139, http://www.ncbi.nlm.nih.gov/pubmed/23427861
"Hydrophosphination of Propargylic Alcohols and Amines with Phosphine Boranes," Busacca, C. A.; Qu, B.; Farber, E.; Haddad, N.;Gret, N.; Saha, A. K.; Eriksson, M. C.; Wu, J.-P.; Fandrick, K. R.; Has, S.; Grinber, N.; Ma, S.; Lee, H.; Li, Z.; Spinelli, M.; Gold, A.; Wang, G.; Wipf, P.; Senanayake, C.H., Org. Lett, Vol. 15, 2013, Pages (5), 1132-1135, http://pubs.acs.org/doi/pdfplus/10.1021/ol400309y
"Influence of Base and Structure in the Reversible Covalent Conjugate Addition of Thiol to Polycyclic Enone Scaffolds," Rosenker, C. J.; Krenske, E. H.; Houk, K. N.; Wipf, P., Org. Lett., Vol. 15, 2013, Pages (5), 1076-1079, http://pubs.acs.org/doi/pdfplus/10.1021/ol400094k
"TargetHunter: An In Silico Target Identification Tool for Predicting Therapeutic Potential of Small Organic Molecules Based on Chemogenomic Database," Wang, L.; Ma, C. Wipf, P.; Liu, H.; Su, W.; Xie, X.-Q., AAPSJ, 2013, http://www.ncbi.nlm.nih.gov/pubmed/23292636
"Mitochondrial-derived Reactive Oxygen Species (ROS) Play a Causal Role in Aging-related Intervertebral Disc Degeneration," Nasto, L. A.; Robinson, A.; Ngo, K.; Clausen, C. L.; Dong, Q.; St. Croix, C.; Sowa, G.; Pola, E.; Robbins, P. D.; Kang, J.; Niedernhofer, L. J.; Wipf, P.; Vo, M. V. , J. Orthopaed. Res. , 2013, http://www.ncbi.nlm.nih.gov/pubmed/23389888
"Cycloadditions in Heterocycle and Alkaloid Synthesis," Wipf, P.; Fang, Z.; Ferrié, L.; Ueda, M.; Walczak, M. A. A.; Yan, Y.; Yang, M., Pure Appl. Chem, Vol. 85, 2013, http://pac.iupac.org/publications/pac/pdf/asap/pdf/PAC-CON-12-09-03.pdf
"Nanoassembly of Surfactants with Interfacial Drug-Interactive Motifs as Tailor-Designed Drug Carriers," Gao, X.; Huang, Y.; Makhov, A. M.; Epperly, M.; Lu, J.; Grab, S.; Zhang, P.; Rohan, L.; Xie, X.-Q.; Wipf, P.; Greenberger, J.; Li, S., S. Mol. Pharm., Vol. 10, 2013, Pages 187-198, http://www.ncbi.nlm.nih.gov/pubmed/23244299
"5-Hydroxyindoles by Intramolecular Alkynol-Furan Diels-Alder Cycloaddition," LaPorte, M.; Hong, K. B.; Xu, J.; Wipf, P., J. Org. Chem. (Prof. Robert E. Ireland Memorial Issue), Vol. 78, 2013, Pages (1), 167-174, http://pubs.acs.org/doi/pdfplus/10.1021/jo3022605
"Memory of Chirality in Rebound Cyclizations of α-Amide Radicals," Sasmal, A.; Taniguchi, T.; Wipf, P.; Curran, D. P., Can. J. Chem. (Prof. Derrick Clive Special Issue), Vol. 91, 2013, Pages (1), 1-5, http://www.nrcresearchpress.com/doi/pdf/10.1139/v2012-085
"In Vitro Cytotoxicity, Pharmacokinetics, Tissue Distribution, and Metabolism of Small-Molecule Protein Kinase D Inhibitors, kb-nb142-70 and kb-nb165-09, in Mice Bearing Human Cancer Xenografts," Guo, J.; Clausen D. M.; Beumer J. H.; Parise R. A.; Egorin M. J.; Bravo-Altamirano, K.; Wipf, P.; Sharlow E. R.; Wang Q. J.; Eiseman J. L. , Cancer Chemother. Pharmacol, Vol. 71, 2013, Pages (2), 331-344, http://link.springer.com/article/10.1007%2Fs00280-012-2010-z?LI=true#page-1
"New Calcium Channel Agonists as Potential Therapeutics in Lambert-Eaton Myasthenic Syndrome and other Neuromuscular Diseases," Tarr, T. B.; Valdomir, G.; Liang, M.; Wipf, P.; Meriney, S. D., Ann. N. Y. Acad. Sci. , Vol. 1275, 2012, Pages (1), 85-91, http://www.ncbi.nlm.nih.gov/pubmed/23278582
"Synthesis and Biological Evaluation of a Selective N- and P/Q-Type Calcium Channel Agonist," Liang, M.; Tarr, T. B.; Bravo-Altamirano, K.; Valdomir, G.; Rensch, G.; Swanson, L.; DeStefino, N. R.; Mazzarisi, C. M.; Olszewski, R. A.; Wilson, G. M.; Meriney, S. D.; Wipf, P., ACS Me. Chem. Lett., Vol. 3, 2012, Pages (12), 985-990, http://pubs.acs.org/doi/pdfplus/10.1021/ml3002083
"A Targeted Library Screen Reveals a New Inhibitor Scaffold for Protein Kinase D," Tandon, M.; Wang, L.; Xu, Q.; Xie, X.; Wipf, P.; Wang, Q. J., PLoS One , Vol. 7, 2012, Pages (9), e44653, http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0044653
"Targeting of XJB-5-131 to Mitochondria Suppresses Oxidative DNA Damage and Motor Decline in a Mouse Model of Huntington’s Disease," Xun, Z.; Rivera-Sanchez, S.; Ayala-Penã, S.; Lim, J.; Budworth, H.; Skoda, E. M.; Robbins, P. D.; Niedernhofer, L. J.; Wipf, P.; McMurray, C. T. , Cell Rep. , Vol. 2, 2012, Pages (5), 1137-1142, http://www.ncbi.nlm.nih.gov/pubmed/23122961
"Global Lipidomics Identifies Cardiolipin Oxidation as a Mitochondrial Target for Redox Therapy of Acute Brain Injury," Ji, J.; Kline, A. E.; Amoscato, A.; Arias, A. S.; Sparvero, L. J.; Tyurin, V. A.; Tyrina, Y. Y.; Fink, B.; Cheng, J. P.; Alexander, H.; Clark, R. S. B.; Kochanek, P. M.; Wipf, P.; Kagan, V. E.; Bayir, H., Nat. Neurosci. , Vol. 15, 2012, Pages (10), 1407-1413, http://www.nature.com/neuro/journal/v15/n10/full/nn.3195.html?WT.ec_id=NEURO-201...
"Structural Basis of Functional Group Activation by Sulfotransferases in Complex Metabolic Pathways," Mccarthy, J. G.; Eisman, E. B.; Kulkarni, S.; Gerwick, L.; Gerwick, W. H.; Wipf, P.; Sherman, D. H.; Smith, J. L. , ACS Chem. Biol., Vol. 7, 2012, Pages (12), 1994-2003, http://www.ncbi.nlm.nih.gov/pubmed/22991895
"Lipophilicity Screening of Novel Drug-Like Compounds and Comparison to cLog P," Lu, D.; Chambers, P.; Wipf, P.; Xie, X.-Q.; Englert, D.; Weber, S. , J. Chromatogr. A, Vol. 1258, 2012, Pages 161-167, http://www.ncbi.nlm.nih.gov/pubmed/22939208
"Synthesis of a Library of Tricyclic Azepinoisoindolinones," Miller, B.; Mao, S.; Rosenker, K. M. G.; Pierce, J. G.; Wipf, P. , Beilstein J. Org. Chem. (Special Issue on Recent Developments in Chemical Diversity) , Vol. 8, 2012, Pages 1091-1097, http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3458725/
"Diversity-Oriented Synthesis of Peptidomimetics: How and Why," Wipf, P. , DOS, Vol. 1, 2012, Pages 6-10, http://www.degruyter.com/view/j/dos.2012.1.issue/dos-2012-0002/dos-2012-0002.xml
"A Screen for Modulators of Large T Antigen’s ATPase Activity Uncovers Novel Inhibitors of Simian Virus 40 and BK Virus Replication," Seguin, S. P.; Ireland, A. W.; Miyata, Y.; Wipf, P.; Pipas, J. M.; Gestwicki, J. E.; Brodsky, J. L., Antivir. Res. , Vol. 96, 2012, Pages 70-81, http://www.ncbi.nlm.nih.gov/pubmed/22898086
"Geographic Variability and Anti-Staphylococcal Activity of the Chrysophaentins and Their Synthetic Fragments," Keffer, J. L.; Hammill, J. T.; Lloyd, J. R.; Plaza, A.; Wipf, P.; Bewley, C. A., Mar. Drugs , Vol. 10, 2012, Pages (5), 1103-1125, http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3397459/
"A Bifunctional Dimethylsulfoxide Substitute Enhances the Aqueous Solubility of Small Organic Molecules," Sprachman, M. M.; Wipf, P., ASSAY Drug Dev. Technol., Vol. 10, 2012, Pages (3), 269-277, http://www.ncbi.nlm.nih.gov/pubmed/22192308
"Strategies for Discovery of Small Molecule Radiation Protectors and Radiation Mitigators," Greenberger, J. S.; Clump, D.; Kagan, V.; Bayir, H.; Lazo, J. S.; Wipf, P.; Li, S.; Gao, X.; Epperly, M. W. , Front. Oncol. , Vol. 1, 2012, Pages Article 59, 1-12, http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3356036/
"Synthesis of 1,2,4-Triazines and the Triazinoisoquinolinedione DEF Ring System of Noelaquinone," Cao, L.; Maciejewski, J. P.; Elzner, S.; Amantini, D.; Wipf, P., Org. Biomol. Chem. (Special 10 Year Anniversary Issue), Vol. 10, 2012, Pages 5811-5814, http://www.ncbi.nlm.nih.gov/pubmed/22473572
"Selenosemicarbazones as Potent Cruzipain Inhibitors and Their Antiparasitic Properties against Trypanosoma cruzi," Pizzo, C.; Faral-Tello, P.; Salinas, G.; Flo, M.; Robello, C.; Wipf, P.; Mahler, S. G. , MedChemComm, Vol. 3, 2012, Pages 362-368, http://pubs.rsc.org/en/content/articlepdf/2012/md/c2md00283c
"Allylic Amines as Key Building Blocks in the Synthesis of (E)-Alkene Peptide Isosteres," Skoda, E. M.; Davis, G. C.; Wipf, P. , Org. Proc. Res. Dev. , Vol. 16, 2012, Pages (1), 26-34, http://pubs.acs.org/doi/pdf/10.1021/op2002613
"Linear and Nonlinear Support Vector Machine for the Classification of Human 5-HT1a Ligand Functionality," Wang, L.; Ma, C.; Wipf, P.; Xie, X.-Q. , Mol. Informatics , Vol. 31, 2012, Pages 85-95, http://onlinelibrary.wiley.com/doi/10.1002/minf.201100126/pdf
"Genetically Encoded Redox Sensor Identifies the Role of ROS in Degenerative and Mitochondrial Disease Pathogenesis," Liu, Z.; Celotto, A. M.; Romero, G.; Wipf, P.; Palladino, M. J., Neurobiol. Dis. , Vol. 45, 2012, Pages (1), 362-368, http://www.ncbi.nlm.nih.gov/pubmed/21889980
"Structure-Activity Relationships amongst 4-Position Quinoline Methanol Antimalarials that Inhibit the Growth of Drug Sensitive and Resistant Strains of Plasmodium Falciparum.," Milner, E.; McCalmont, W.; Bhonsle, J.; Caridha, D.; Carroll, D. W.; Gardner, S.; Gerena, L.; Gettayacamin, M.; Lanteri, C.; Luong, T.; Melendez, V.; Moon, J. K.; Roncal, N. E.; Sousa, J. C.; Tangteung, A.; Wipf, P.; Dow, G. S., Bioorg. Med. Chem. Lett., Vol. 20, 2010, Pages (4), 1347-1351, http://www.sciencedirect.com/science?_ob=MImg&_imagekey=B6TF9-4Y3TX68-2-S&_cdi=5...
"Regioselective Palladium-Catalyzed Cross-Coupling Reactions of 2,4,7-Trichloroquinazoline.," Wipf, P.; George, K. M., Synlett (Special Issue Honoring G. Pattenden), 2010, Pages 644-648,
"Screening of Antimicrobial Agents for In Vitro Radiation Protection and Mitigation Capacity, Including those Used in Supportive Care Regimens for Bone Marrow Transplant Recipients.," Epperly, M. W.; Franicola, D.; Shields, D.; Rwigema, J.-C.; Zhang, X.; McBride, W.; Georges, G.; Wipf, P.; Greenberger, J. S. , In Vivo, Vol. 24, 2010, Pages (1), 9-19,
"Transmetalation Reactions Producing Organocopper Compounds.," Rosenker, C. J.; Wipf, P. In "Patai Series: The Chemistry of Functional Groups. The Chemistry of Organocopper Compounds", Rappoport, Z.; Marek, I., Eds., Wiley Interscience, 2010, Pages Part 1, Chapter 10, pp 443-525,
"Peptide-Like Molecules (PLMs): A Journey from Peptide Bond Isosteres to Gramicidin S Mimetics and Mitochondrial Targeting Agents," Wipf, P.; Xiao, J.; Stephenson, C. R. J. , Chimia , Vol. 63, 2009, Pages 764-775,
"Phosphatases as Targets for Cancer Treatment," Lazo, J. S.; Wipf, P., Curr. Op. Invest. Drugs, Vol. 10, 2009, Pages 1297-1304,
"Mitochondrial Targeting of Electron Scavenging Antioxidants: Regulation of Selective Oxidation vs Random Chain Reactions," Kagan, V. E.; Wipf, P.; Stoyanovsky, D.; Greenberger, J. S.; Borisenko, G.; Belikova, N. A.; Yanamala, N.; Samhan Arias, A. K.; Tungekar, M. A.; Jiang, J.; Tyurina, Y. Y.; Ji, J.; Klein-Seetharaman, J.; Pitt, B. R.; Shvedova, A. A.; Bayir, H. , Adv. Drug Deliv. Rev, Vol. 61, 2009, Pages 1375-1385,
"The Mitochondria-Targeted Nitroxide JP4-039 Augments Potentially Lethal Irradiation Damage Repair," Rajagopalan, M. S.; Gupta, K.; Epperly, M. W.; Franicola, D.; Zhang, X.; Wang, H.; Zhao, H.; Tyurin, V. A.; Pierce, J. G.; Kagan, V. E.; Wipf, P.; Kanai, A. J.; Greenberger, J. S., In Vivo , Vol. 23, 2009, Pages 717-726,
"Synthesis of Pyrrolo[1,3]diazepines by a Dipolar Cycloaddition – retro-Mannich Domino Reaction," Liang, M.; Saiz, C.; Pizzo, C.; Wipf, P. , Tetrahedron Lett. , Vol. 50, 2009, Pages 6810-6813,
"Reversible Thiazolidine Exchange: A New Reaction Suitable for Dynamic Combinatorial Chemistry," Saiz, C.; Wipf, P.; Manta, E.; Mahler, G. , Org. Lett., Vol. 11, 2009, Pages 3170-3173,
"Synthesis and Biological Evaluation of the First Pentafluorosulfanyl Analogs of Mefloquine," Wipf, P.; Mo, T.; Geib, S. J.; Caridha, D.; Dow, G. S.; Gerena, L.; Roncal, N.; Milner, E. E. , Org. Biomol. Chem. , Vol. 7, 2009, Pages 4163-4165,
"Evaluating b-Turn Mimics as b-Sheet Folding Nucleators," Fuller, A. A.; Du, D.; Liu, F.; Davoren, J. E.; Bhabha, G.; Kroon, G.; Case, D. A.; Dyson, H. J.; Powers, E. T.; Wipf, P.; Gruebele, M.; Kelly, J. W. , Proc. Natl. Acad. Sci. USA , Vol. 106, 2009, Pages 11067-11072,
"Optical Signatures of Molecular Dissymmetry: Combining Theory with Experiments to Address Stereochemical Puzzles," Mukhopadhyay, P.; Wipf, P.; Beratan, D. N., Acc. Chem. Res. , Vol. 42, 2009, Pages 809-819,
"Metamorphic Enzyme Assembly in Polyketide Diversification," Gu, L.; Wang, B.; Kulkarni, A.; Geders, T. W.; Grindberg, R. V.; Gerwick, L.; Hakansson, K.; Wipf, P.; Smith, J. L.; Gerwick, W. H.; Sherman, D. H. , Nature , Vol. 459, 2009, Pages 731-735,
"Nanoparticles in Cellular Drug Delivery," Faraji, A. H.; Wipf, P., Bioorg. Med. Chem. , Vol. 17, 2009, Pages 2950-2962,
"Cytochrome C/Cardiolipin Relations in Mitochondria: a Kiss of Death," Kagan, V. E.; Bayir, H.; Belikova, N. A.; Kapralov, A.; Tyurina, Y. Y.; Tyurin, V. A.; Jiang, J.; Stoyanovsky, D.; Wipf, P.; Kochanek, P. M.; Borisenko, G. G.; Greenberger, J. S.; Shvedova, A. A.; Borisenko, G., G. Mol. Free Rad. Biol. Med. , Vol. 46, 2009, Pages 1439-1453,
"Isolation, Biology and Chemistry of the Disorazoles: New Anti-Cancer Macrodiolides," Hopkins, C. D.; Wipf, P. , Nat. Prod. Rep. , Vol. 26, 2009, Pages 585-601,
"Select pyrimidinones inhibit the propagation of the malarial parasite, Plasmodium falciparum," Chiang, A.N., Valderramos, J.-C., Balachandran, R., Chovatiya, R.J., Mead, B.P., Schneider, C., Bell, S.L., Klein, M.G., Huryn, D.M., Chen, X.S., Day, B.W., Fidock, D.A., Wipf, P., Brodsky, J.L., Bioorg. Med. Chem., Vol. 17, 2009, Pages 1527-1533,
"Synthesis and Biological Evaluation of Inhibitors of Botulinum Neurotoxin Metalloprotease," Wang, C.; Widom, J.; Petronijevic, F.; Burnett, J. C.; Nuss, J. E.; Bavari, S.; Gussio, R.; Wipf, P., Heterocycles (Special Issue Honoring J. Daly), Vol. 79, 2009, Pages 487-520,
"A Microwave Assisted Intramolecular-Furan-Diels-Alder Approach to 4-Substituted Indoles," Petronijevic, F.; Timmons, C.; Cuzzupe, A.; Wipf, P., Chem. Commun. , Vol. 1, 2009, Pages 104-106,
"Triple Hybrids of Steroids, Spiroketals, and Oligopeptides as New Biomolecular Chimeras," Banerjee, A.; Sergienko, E.; Vasile, S.; Gupta, V.; Vuori, K.; Wipf, P., Org. Lett. , Vol. 11, 2009, Pages 65-68,
"Formal Alder-Ene Reaction of a Bicyclo[1.1.0]butane in the Synthesis of the Tricyclic Quaternary Ammonium Core of Daphniglaucin," Ueda, M.; Walczak, M. A. A.; Wipf, P. , Tetrahedron Lett., Vol. 49, 2008, Pages 5986-5989,
"Rhodium(I)-Catalyzed Cycloisomerizations of Bicyclobutanes," Walczak, M. A. A.; Wipf, P., J. Am. Chem. Soc. , Vol. 130, 2008, Pages 6924-6925,
"Targeting Mitochondria," Hoye, A. T.; Davoren, J.; Wipf, P.; Fink, M. P.; Kagan, V. E. , Acc. Chem. Res., Vol. 41, 2008, Pages 87-97,