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招生专业 071007-遗传学 071008-发育生物学 071009-细胞生物学 招生方向 表观遗传学,表观基因组学,发育生物学,染色质 教育背景 2004-09--2011-07 中国科学院大学/中国科学院遗传与发育生物学研究所 博士 2000-09--2004-06 北京大学 学士 奖励信息 (1) Harvard Chinese Life Science YongJin Distinguished Research Award, , 其他, 2016 (2) 北京市科学技术奖, 二等奖, 省级, 2015

研究领域

表观遗传与细胞命运决定

近期论文

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(1) Maternal H3K27me3 controls DNA methylation-independent imprinting., Nature, 2017, 第 3 作者 (2) Genomic imprinting of Xist by maternal H3K27me3, Genes & Development, 2017, 第 3 作者 (3) Establishing chromatin regulatory landscape during mouse preimplantation development, Cell, 2016, 第 1 作者 (4) REF6 recognizes specific DNA sequence to regulate H3K27me3 demethylation and organ boundary formation, Nature Genetics, 2016, 第 2 作者 (5) Loss of HDAC-Mediated Repression and Gain of NF-kappaB Activation Underlie Cytokine Induction in ARID1A- and PIK3CA-Mutation-Driven Ovarian Cancer, Cell Reports, 2016, 第 2 作者 (6) Drosophila Homolog of FMRP Maintains Genome Integrity by Interacting with Piwi, Journal of Genetics and Genomics, 2016, 第 2 作者 (7) Cell totipotency: molecular features, induction, and maintenance, National Science Review, 2015, 第 1 作者 (8) Histone Demethylase Expression Enhances Human Somatic Cell Nuclear Transfer Efficiency and Promotes Derivation of Pluripotent Stem Cells, Cell Stem Cell, 2015, 第 5 作者 (9) C-terminal domains of histone demethylase JMJ14 interact with a pair of NAC transcription factors to mediate specific chromatin association, Cell Discovery, 2015, 第 10 作者 (10) Role of Tet proteins in enhancer activity and telomere elongation, Genes & Development, 2014, 第 1 作者 (11) Embryonic Development following Somatic Cell Nuclear Transfer Impeded by Persisting Histone Methylation, Cell, 2014, 第 3 作者 (12) Tet3 and DNA Replication Mediate Demethylation of Both the Maternal and Paternal Genomes in Mouse Zygotes, Cell Stem Cell, 2014, 第 5 作者 (13) Arabidopsis protein arginine methyltransferase 3 is required for ribosome biogenesis by affecting precursor ribosomal RNA processing, Proc Natl Acad Sci U S A, 2014, 第 5 作者 (14) Ubiquitin-specific proteases UBP12 and UBP13 act in circadian clock and photoperiodic flowering regulation in Arabidopsis, Plant Physiology, 2013, 第 2 作者 (15) The enzymatic activity of Arabidopsis protein arginine methyltransferase 10 is essential for flowering time regulation, Protein & Cell, 2012, 第 2 作者 (16) Crystal Structure of the Plant Epigenetic Protein Arginine Methyltransferase 10, Journal of Molecular Biology, 2011, 第 3 作者 (17) Arabidopsis REF6 is a Histone H3 Lysine 27 Demethylase, Nature Genetics, 2011, 第 1 作者 (18) Histone methylation in higher plants, Annual Review of Plant Biology, 2010, 第 2 作者 (19) Autocatalytic differentiation of epigenetic modifications within the Arabidopsis genome, EMBO Journal, 2010, 第 4 作者 (20) Arginine methylation mediated by the Arabidopsis homolog of PRMT5 is essential for proper pre-mRNA splicing, Proc Natl Acad Sci U S A, 2010, 第 5 作者 (21) JMJ14 is an H3K4 demethylase regulating flowering time in Arabidopsis, Cell Research, 2010, 第 1 作者 (22) Comparative analysis of JmjC domain-containing proteins in higher plants and human reveals potential histone demethylases in Arabidopsis and rice, Journal of Integrative Plant Biology, 2008, 第 1 作者 (23) Regulation of Flowering Time by a Protein Arginine Methyltransferase, AtPRMT10, EMBO Reports, 2007, 第 2 作者 (24) Mutations in the Type II protein arginine methyltransferase AtPRMT5 result in pleiotropic developmental defects in Arabidopsis thaliana, Plant Physiology, 2007, 第 3 作者

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