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个人简介

1965年毕业于复旦大学生物系遗传专业以来,一直在中国科学院遗传研究所工作。1988年破格晋升为研究员,1996年被国家人事部授予有突出贡献中青年专家称号。1986-1987年比利时根特大学遗传系访问学者,1989—1992年在美国康乃尔大学植物育种系做客座研究(每年三个月)。曾先后任遗传所学术委员会主任和副所长,中国科学院遗传所、微生物所植物生物技术重点实验室,中国科学院遗传与发育生物学研究所学术委员会主任,植物基因组学国家重点实验室学术委员会主任;也曾任职中国生物工程学会副秘书长,"遗传学报"和"遗传"两刊主编。2008年3月起任荣誉研究员。 其领导的研究组长期以来一直从事水稻的遗传学和基因组学研究,已在国际SCI刊物上发表论文60篇以上。从2000年起,作为发起人之一与北京基因组研究所等单位一起组织并完成了籼稻93-11基因组的测序,有关论文发表在Science(2002,296:79-92)上,现已成功地克隆了多个水稻重要性状的功能基因。近年来的主要研究领域是与水稻发育和抗病相关的分子遗传学和功能基因组学;通过正向和反向遗传学的途径研究水稻抗病基因的功能及其介导的抗病信号网络,并开展与水稻的花器官分化相关的基因的功能研究。

研究领域

研究方向:植物发育和抗病分子遗传学

近期论文

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KEYPUBLICATIONS LanYin,YingLan,LihuangZhu.Analysisoftheproteinexpressionprofilingduringricecallusdifferentiationunderdifferentplanthormoneconditions.PlantMolBiol.2008,68:597–617 DejunLi,ChunhuaYang,XiaobingLi,GuobiaoJi,LihuangZhu.SenseandantisenseOsDof12transcriptsinrice.BMCMolecularBiology,2008,9:80 XiangT,ZongN,ZouY,WuY,ZhangJ,XingW,LiY,TangX,ZhuL,ChaiJ,ZhouJM.PseudomonassyringaeeffectorAvrPtoblocksinnateimmunitybytargetingreceptorkinases.CurrBiol.,2008,18(1):74-80. L.Wan,D,Y.Li,D.L.Zhang,X.Liu,W.J.Fu,L.H.Zhu,M.H.Deng,F.Z.Sun,M.P.Qian.Conservationandimplicationsofeukaryotetranscriptionalregulatoryregionsacrossmultiplesoecies.BMCGenomics.2008,9:623 WeimanXing,YanZou,QunLiu,JianingLiu,XiLuo,QingqiuHuang,SheChen,LihuangZhu,RuchangBi,QuanHao,Jia-WeiWu,Jian-MinZhou&JijieChai(2007)ThestructuralbasisforactivationofplantimmunitybybacterialeffectorproteinAvrPto,Nature449,243-247 Yin,L.,Tao,Y.,Zhao,K.,Shao,J.,Xu,G.,Li,X.,Liu,G.,Liu,S.,Zhu,L*.(2007)Proteomicandtranscriptomicanalysisofricematureseed-derivedcallusdifferentiation.Proteomics7,755-768. JunhuangZou,ShuyingZhang,WeipingZhang,GangLi,ZhongxiangChen,WenxueZhai,XianfengZhao,XuebiaoPan,LihuangZhu*.(2006)ThericsHigh-TilleringDwarf1encodinganothologofArabidopsisMAX3isrequiedfornegativeregulationofoutgrowthaxillarybuds.ThePlantJournal48:687-696. XueweiChen,JunjunShang,DexiChen,CailinLei,YanZou,WenxueZhai,GuozhenLiu,JIchenXu,,ZhongzhuanLing,GangCao,BingtianMa,YupingWang,XianfenZhao,ShiguiLi,LihuangZhu*.AB-lectinreceptorkinasegeneconferringriceblastresistance.ThePlantJournal(2006)46:794-804 CaiyanChen,HanXiao,WenliZhang,AijuWang,ZhihuiXia,XiaobingLi,WenxueZhai,ZhukuanCheng,LihuangZhu*.AdaptingriceantherculturetogenetransformationandRNAinterference.ScienceinChinaSeriesC:LifScience(2006)49,414-428 JiangGuangHuai,XiaZhiHui,ZhouYongLi,WanJia,LiDaYong,ChenRunSheng,ZhaiWenXueandZhuLiHuang*.Testifyingthericebacterialblightresistancegenexa5initsfunctionandfurtheranalyzingxa5(Xa5)bycomparingwithit’shomologTFIIAγ1.MolGenGenomics(2006)275:354-366. JiabinTang,Hong’aiXia,DayongLi,MengliangCao,WeiTong,XiuqingZhang,SongnianHu,JianWang,JunYu,HuanmingYang,LihuangZhu*Geneexpressionprofilinginriceyoungpanicleandvegetativeorgansandidentificationofpanicle-specoficgenesthroughknowngenefunctions.MolGenGenomics(2005)274:467-476 JunhuangZou,ZengxiangChen,ShuyingZhang,WeipingZhang,GuanghuaiJiang,XingfengZhao,WexueZhai,XuebiaoPen,LihuangZhu*Characterizationsandfinemappingofamutantgeneforhigh-tilleringanddwarfinrice(OryzasativaL.)Planta(2005)222:604-612 QiongLuo,KaidaZhou,XianfengZhao,QianchunZheng,HongaiXia,WenxueZhai,JichenXu,XianjunWu,HongsongYang,LihuangZhu*Identificationandfine-mappingofamutantgeneforpalealessspikeletinricePlanta(2005)221:222-230 JiabinTang,HongaiXia,MengliangCao,XiuqingZhang,WanyongZeng,SongnianHu,WeiTong,JunWang,JunYu*,HuanmingYang*andLihuangZhu*.AcomparisonofriceChloroplastGenomes.PlantPhysiology(2004)135:412-420 XianwuZheng,XueweiChen,XiaohongZhang,ZhongzhuanLin,JinjunShang,JichenXu,WenxueZhaiandLihuangZhu*.Isolationandidentificationofageneinresponsetoriceblastdiseaseinrice.PlantMolecularBiology(2004)54:99-109 PingHe,SatyaChintamanani.ZhongyingChen,LihuangZhu,BarbaraNKunkel,JamesRAlfano,XiaoyanTang,Jian-MinZhou*.ActivationofaCOL1-depedentpathwayinArabdopsisbyPseudomonassyringaetypeIIIeffectorsandcoronatine.TheplantJournal(2004)37:589-602 H.Xiao,Y.Wang,D.F.Liu,W.M.Wang,X.B.Li,X.F.Zhao,J.C.Xu,W.X.Zhai,L.H.Zhu*.FunctionalanalysisofthericeAP3homologueOsMADS16byRNAinterference.PlantMolecularBiology(2003)52:957-966 YuJ,HuS,WangJ,WongGK,LiS,LiuB,DengY,DaiL,ZhouY,ZhangX,CaoM,LiuJ,SunJ,TangJ,ChenY,HuangX,LinW,YeC,TongW,CongL,GengJ,HanY,LiL,LiW,HuG,LiJ,LiuZ,QiQ,LiT,WangX,LuH,WuT,ZhuM,NiP,HanH,DongW,RenX,FengX,CuiP,LiX,WangH,XuX,ZhaiW,XuZ,ZhangJ,HeS,XuJ,ZhangK,ZhengX,DongJ,ZengW,TaoL,YeJ,TanJ,ChenX,HeJ,LiuD,TianW,TianC,XiaH,BaoQ,LiG,GaoH,CaoT,ZhaoW,LiP,ChenW,ZhangY,HuJ,LiuS,YangJ,ZhangG,XiongY,LiZ,MaoL,ZhouC,ZhuZ,ChenR,HaoB,ZhengW,ChenS,GuoW,TaoM,ZhuL*.,YuanL*.,YangH*.Adraftsequenceofthericegenome(OzyzasativaL.ssp.indica)Science(2002)296:79-92 ChengZ.K,Yan,,H.H,Yu,H.X,Tang,S.C,Jing,J.M,Gu,M.H.,andZhu,L.H*.Developmentandapplicationofacompletesetofricetelotrisomis.Genetics(2001)157∶361-368 Wang.W.M.,Zhai.W.X.,Luo.M.Z.,Jiang.G.H.,Chen.X.W.,Li.X.B.,Wing.R.A.andZhu.L.H*.ChromosomeLandingatthebacterialblightResistanceGeneXa4locusUsingadeepcoverageviceBAClibrary.MGG(2001)265∶118-125

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