个人简介
简历:
汉族,博士。现任中国科学院新疆理化技术研究所副研究员(项目聘用)。近年来,主持或参与国家、省部级课题6项。曾获军队科技进步二等奖1项;新疆维吾尔自治区科技进步三等奖1项,新疆第六届青年学术年会优秀学术论文二等奖1项;新疆维吾尔自治区自然科学优秀学术论文三等奖1项;发明专利4项;
代表性专利:
1.贺耀武,曹玲华,窦君,阿吉艾克拜尔·艾萨,芳基四唑糖基衍生物及其制备方法和用途,2013.04.03,中国,CN101723995B
2.阿吉艾克拜尔·艾萨;程珍;阿布力米提·伊力;吕俏莹;高彦华;窦君,一种鹰嘴豆豆芽有效成分的纯化方法,2012.04.18,中国,CN102000138B,
3.阿吉艾克拜尔·艾萨;阿布力米提·伊力;程珍;毛人杰;窦君,鹰嘴豆豆芽有效部位及其制备方法和应用,2012.04.18,中国,CN102068486B
4.阿吉艾克拜尔·艾萨;程珍;吕俏莹;阿布力米提·伊力;窦君,一种鹰嘴豆总皂苷的制备方法,2011.09.07,中国,CN101991635B
近期论文
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代表性文章:
(1)ChenZ,WangL,YaoD,YangT,CaoWM,DouJ,PangJC,GuanS,ZhangH,YuY,ZhaoY,WangY,XuX,ShiY,PatelR,ZhangH,VasudevanSA,LiuS,YangJ,NuchternJG.Wip1inhibitorGSK2830371inhibitsneuroblastomagrowthbyinducingChk2/p53-mediatedapoptosis.SciRep.2016Dec19;6:38011.doi:10.1038/srep38011.
(2)NiuC,PangGX,LiG,DouJ,NieLF,HimitH,KabasM,AisaHA.SynthesisandbiologicalevaluationoffurocoumarinderivativesonmelaninsynthesisinmurineB16cellsforthetreatmentofvitiligo.BioorgMedChem.2016Nov15;24(22):5960-5968.doi:10.1016/j.bmc.2016.09.056.Epub2016Sep23
(3)NiuC,YinL,NieLF,DouJ,ZhaoJY,LiG,AisaHA.SynthesisandbioactivityofnovelisoxazolechalconederivativesontyrosinaseandmelaninsynthesisinmurineB16cellsforthetreatmentofvitiligo.BioorgMedChem.2016Nov1;24(21):5440-5448.doi:10.1016/j.bmc.2016.08.066.Epub2016Sep1.
(4)WangH,YuY,JiangZ,CaoWM,WangZ,DouJ,ZhaoY,CuiY,ZhangH.Next-generationproteasomeinhibitorMLN9708sensitizesbreastcancercellstodoxorubicin-inducedapoptosis.SciRep.2016May24;6:26456.doi:10.1038/srep26456.
(5)ZhangH,DouJ,YuY,ZhaoY,FanY,ChengJ,XuX,LiuW,GuanS,ChenZ,shiY,PatelR,VasudevanSA,ZagePE,ZhangH,NuchternJG,KimES,FuS,YangJ.mTORATP-competitiveinhibitorINK128inhibitsneuroblastomagrowthviablockingmTORCsignaling.Apoptosis.2015,20(1):50-62.
(6)ChengJ,FanY-H,XuX,ZhangH,DouJ,TangY,ZhongX,RojasY,YuY,ZhaoYVasudevan,SA,ZhangH,NuchternJG,KimES,ChenX,LuF,YangJ.AsmallmoleculeinhibitorofUBE2Ninducesneuroblastomacelldeathviaactivationofp53andJNKpathways.CellDeathandDisease(2014)5,e1079;doi:10.1038/cddis.2014.54
(7)FanYH,ChengJ,VasudevanSA,DouJ,ZhangH,PateRH,MaIT,RojasY,ZhaoY,YuY,ZhangH,ShohetJM,NuchternJG,KimES,YangJ.USP7inhibitorP22077inhibitsneuroblastomagrowthviainducingp53-mediatedapoptosis.CellDeathandDisease(2013)4,e867;doi:10.1038/cddis.2013.400.
(8)ZhaoY,DouJ,WuT,AisaHA.InvestigatingtheAntioxidantandAcetylcholinesteraseInhibitionActivitiesofGossypiumherbaceam.Molecules,2013,18(1):951-962.
(9)LinJ,DouJ,XuJ,AisaHA.ChemicalComposition,AntimicrobialandAntitumorActivitiesoftheEssentialOilsandCrudeExtractsofEuphorbiamacrorrhiza.Molecules,2012,17:5030-5039.