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个人简介

教育背景 1995-1999年,华东理工大学化工系,学士 1999-2002年,中国科学院过程工程研究所生化国家重点实验室,硕士 2002-2003年,美国宾夕法尼亚州立大学(PSU)农业与生物工程系,博士学习 2003-2006年,新加坡国立大学(NUS)化工与生物分子工程系,博士 工作经历 2007-2009,Lee Kuan Yew Postdoctoral Fellow, Singapore 2009.1-至今,北京化工大学材料科学与工程学院,教授,博士生导师 2014.5-至今, 生物医用材料北京实验室执行主任 2014.11-2015.6,北京化工大学材料学院生物材料系,主任 2015.7-2019.6,北京化工大学材料学院副院长 2019.7-2020.6,北京化工大学材料学院常务副院长 2017.12-2019.10,北京化工大学-中日友好医院生物医学转化工程研究中心主任 2018.10-至今,北京化工大学天然高分子医用材料教育部重点实验室主任 2020.7-至今,北京化工大学材料学院院长

研究领域

主要从事医用高分子材料应用基础研究,在药物控释载体、抗菌材料以及多糖功能化方面开展了广泛应用基础研究

近期论文

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Duan, S.; Wu, R.; Xiong, Y.H.; Ren, H.M.; Lei, C.; Zhao, Y.Q.; Zhang, X.Y.; Xu, F.J.* Multifunctional antimicrobial materials: from rational design to biomedical applications. Progress in Materials Science. 2022, 125: 100887 Zhao, X.; Guo, K.; Zhang, K.; Duan, S.; Chen, M.; Zhao, N.N.*; Xu, F.J.* Orchestrated yolk-shell nanohybrids regulate macrophage polarization and dendritic cell maturation for oncotherapy with augmented antitumor immunity. Advanced Materials. 2022, 34: 2108263 Zhu, Y.#; Wu, S.#; Sun, Y.; Zou, X.; Zheng, L.; Duan, S.; Wang, J.; Yu, B.R.*; Sui, R.*; Xu, F.J.* Bacteria-targeting photodynamic nanoassemblies for efficient treatment of multidrug-resistant biofilm infected keratitis. Advanced Functional Materials. 2022, 32: 2111066 Wang, A.; Duan, S.; Ding, X.J.; Zhao, N.; Hu, Y.; Ding, X.*; Xu, F.J.* Bioswitchable antibacterial coatings enable self-sterilization of implantable healthcare dressings. Advanced Functional Materials. 2021, 31(18): 2011165 Zhang, X.; Yao, D.; Zhao, W.Y.; Zhang, R.; Yu, B.; Ma, G.; Li, Y.*; Hao, D.*; Xu, F.J.* Engineering platelet-rich plasma based dual-network hydrogel as a bioactive wound dressing with potential clinical translational value. Advanced Functional Materials. 2021, 31(8): 2009258 Wu, S.; Xu, C.; Zhu, Y.; Zheng, L.; Zhang, L.; Hu, Y.; Yu, B.*; Wang, Y.*; Xu, F.J.* Biofilm-sensitive photodynamic nanoparticles for enhanced penetration and antibacterial efficiency. Advanced Functional Materials. 2021, 31(33): 2103591 Song, H.Q.; Fan, Y.; Hu, Y.*; Cheng, G.*; Xu, F.J.* Polysaccharide-peptide conjugates: a versatile material platform for biomedical applications. Advanced Functional Materials. 2021, 31(6): 2005978 Liu, Z.; Zhao, X.; Yu, B.; Zhao, N.*; Zhang, C.; Xu, F.J.* Rough carbon-iron oxide nanohybrids for near-infrared-II light responsive synergistic antibacterial therapy. ACS Nano. 2021, 15: 7482-7490. Shao, M.; Fan, Y.; Zhang, K.; Hu, Y.*; Xu, F.J.* One nanosystem with potent antibacterial and gene-delivery performances accelerates infected wound healing. Nano Today. 2021, 39: 101224 Zhao, N.N.; Yan, L.; Xue, J.; Zhang, K.*; Xu, F.J.* Degradable one-dimensional dextran-iron oxide nanohybrids for MRI-guided synergistic gene/photothermal/magnetolytic therapy. Nano Today. 2021, 38: 101118 Liu, Y.; Yu, B.; Dai, X.; Zhao, N.*; Xu, F.J.* Biomineralized calcium carbonate nanohybrids for mild photothermal heating-enhanced gene therapy. Biomaterials. 2021,274: 120885 Zheng, L.#; Li, J.#; Yu, M.#; Jia, W.; Duan, S.; Ding, X.; Yu, B.*; Zhang, X.*; Xu, F.J.* Molecular sizes and antibacterial performance relationships of flexible ionic liquid derivatives. Journal of the American Chemical Society. 2020, 142(47): 20257-20269 Zhao, Y.Q.; Sun, Y.; Zhang, Y.; Ding, X.; Zhao, N.N.; Yu, B.; Zhao, H.; Duan, S.;* Xu, F.J.* Well-defined gold nanorod/polymer hybrid coating with inherent antifouling and photothermal bactericidal properties for treating infected hernia. ACS Nano. 2020, 14(2): 2265-2275 Liu, J.Y.#; Hu, Y.#; Li, L; Wang, C.; Wang, J.; Li, Y.*; Chen, D.; Ding, X.; Shen, C.*; Xu, F.J.* Biomass-derived multi-layer-structured microparticles for accelerated hemostasis and bone repair. Advanced Science. 2020, 7(22), 2002243 Qi, Y.#; Liu, Y#; Yu, B.; Hu, Y.; Zhang, N.; Zheng, Y.; Yang, M.*; Xu, F.J.* A lactose-derived CRISPR/Cas9 delivery system for efficient genome editing in vivo to treat orthotopic hepatocellular carcinoma. Advanced Science. 2020, 7(17), 2001424 Xu, C.#; Hu, W.#; Zhang, N.; Qi, Y.; Nie, J.J.; Zhao, N.; Yu, B.*; Xu, F.J.* Genetically multimodal therapy mediated by one polysaccharides-based supramolecular nanosystem. Biomaterials. 2020, 248, 120031 Zhao, N.; Yan, L.; Zhao, X.; Chen, X.; Li, A.; Zheng, D.; Zhou, X.; Dai, X.; Xu, F.J.* Versatile types of organic/inorganic nanohybrids: from strategic design to biomedical applications. Chemical Reviews. 2019, 119(3): 1666-1762 Xu, C.#; Zhang, Y.#; Xu, K.; Nie, J.J.; Yu, B.; Li, S.; Cheng, G.; Li, Y*; Du, J.*; Xu, F. J.* Multifunctional cationic nanosystems for nucleic acid therapy of thoracic aortic dissection. Nature Communications. 2019, 10(1), 3184 Jin, X.#; Xiong, Y.#; Zhang, X.; Wang, R.; Xing, Y.; Duan, S.;* Chen, D.;* Tian, W.; Xu, F.J.* Self-adaptive antibacterial porous implants with sustainable responses for infected bone defect therapy. Advanced Functional Materials. 2019, 29(17): 1807915 Xu, F.J.* Versatile types of hydroxyl-rich polycationic systems via O-heterocyclic ring-opening reactions: from strategic design to nucleic acid delivery applications. Progress in Polymer Science. 2018, 78: 56-91

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