Islam, Kabirul - University of Pittsburgh

个人简介

Awards Visiting Research Fellowship by Starr Cancer Consortium (2010) Graduate Research Fellowship by Council for Scientific and Industrial Research, New Delhi, India (1999-04) Institute Proficiency Prize, Department of Chemistry, Indian Institute of Technology, Kharagpur, India (1999) Institute Silver Medal, Indian Institute of Technology, Kharagpur, India (1999) Summer Research Fellowship, Tata Institute of Fundamental Research, Mumbai, India (1998)

研究领域

Chemical Approaches towards Diagramming Epigenetic Network in Human Development and Disease Organic Synthesis/Bioorganic Chemistry/Small Molecule Therapeutics/Biochemistry/Protein Engineering and ‘Chromatinomics’ (Chromatin-based Proteomics and Genomics)

近期论文

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"Using Azido Analogue of S-Adenosyl-L-methionine for Bioorthogonal Profiling of Protein Methylation," Blum, G.; Islam, K.; Luo, M., Curr. Protoc. Chem. Biol., Vol. 5, 2013, Pages 45, "Profiling chromatin methylation with engineered posttranslation apparatus within living cells.," Wang, R.*; Islam, K.*; Zheng, W.; Liu, Y.; Tang, H.; Blum, Gil.; Deng, H.; Luo, L. (*Equal contribution) , J. Am. Chem. Soc., Vol. 135, 2013, Pages 1048, "Se-adenosyl-L-selenomethionine cofactor analogue as a reporter of protein methylation.," Bothwell, I.; Islam, K.; Cheng, Y.; Zheng, W..; Blum, G.; Deng, H.; Luo, M., J. Am. Chem. Soc., Vol. 134, 2012, Pages 14905, "Bioorthogonal profiling of protein methylation using azido derivative of S-adenosyl-L-methionine.," Islam, K.; Bothwell, I.; Cheng, Y.; Sengelaub, C.; Wang, R.; Deng, H.; Luo, M., J. Am. Chem. Soc., Vol. 134, 2012, Pages 5909, "Expanding cofactor repertoire of protein lysine methyltransferase for substrate labeling.," Islam, K.; Zheng, W.; Yu, H.; Deng, H.; Luo, M., ACS Chem. Biol., Vol. 6, 2011, Pages 679, "Myosin V inhibitor based on ‘privileged’ chemical scaffolds.," Islam, K.; Olivares, A. O.; De La Cruz, E. M.; Kapoor, T. M., Angew. Chem. Int. Ed. Eng., Vol. 49, 2010, Pages 8484, "In situ cryo-crystallization of diphenyl ether: C-H…π mediated polymorphic forms.," Choudhury, A. R.; Islam, K.; Krichner, M. T; Mehta, G.; Guru Row, T. N., J. Am. Chem. Soc., Vol. 126, 2004, Pages 12274, "Enantioselective total synthesis of (-)-Epoxyquinols A and B. Novel, convenient access to chiral epoxyquinone building blocks through enzymatic desymmetrization.," Mehta, G.; Islam, K., Tetrahedron Lett., Vol. 45, 2004, Pages 3611, "Total synthesis of the novel NF-κB inhibitor (-)-Cycloepoxydon.," Mehta, G.; Islam, K., Org. Lett., Vol. 6, 2004, Pages 807, "Enantioselective total syntheses of (+) and (-)-ottelione A and (+) and (-)-ottelione B. Absolute configuration of the novel, biologically active natural products.," Mehta, G.; Islam, K., Tetrahedron Lett., Vol. 44, 2003, Pages 6733, "Total synthesis of novel angiogenesis inhibitors epoxyquinols A and B.," Mehta, G.; Islam, K., Tetrahedron Lett., Vol. 44, 2003, Pages 3569, "Total Synthesis of epi-Otteliones.," Mehta, G.; Islam, K., Org. Lett., Vol. 4, 2002, Pages 2881, "Total synthesis of (+)-otteliones A and B.," Mehta, G.; Islam, K., Angew. Chem. Int. Ed. Eng., Vol. 41, 2002, Pages 2396, "Defining efficient enzyme-cofactor pairs for bioorthogonal profiling of protein methylation," Islam K, Chen Y, Wu H, Bothwell IR, Blum GJ, Zeng H, Dong A, Zheng W, Min J, Deng H, Luo M., Proc Natl Acad Sci U S A., Vol. 110, 2013, Pages 16778-83,