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招生专业 071007-遗传学 招生方向 遗传学,基因组学,动物学 教育背景 1999-09--2004-07 中国科学院昆明动物研究所 理学博士 工作简历 2008-07~现在, 中国科学院昆明动物研究所, 研究员 2007-07~2008-07,德国人类营养研究所, 研究助理 2004-10~2006-12,美国密歇根大学, 博士后 1999-09~2004-07,中国科学院昆明动物研究所, 理学博士 奖励信息 (1) 云南省自然科学奖, 一等奖, 省级, 2014 发表著作 Taste: Topics in Chemical Biology, the Wiley Encyclopedia of Chemical Biology, 2009-07, 第 1 作者 Extraordinary diversity of chemosensory receptor gene repertoires among vertebrates, Chemosensory Systems in Mammals, Fishes, and Insects, 2009-09, 第 1 作者 科研项目 ( 1 ) 哺乳动物化学能感觉系统适应性进化的分子机制, 主持, 国家级, 2010-01--2013-12 ( 2 ) 动物适应性进化的分子系统生物学, 主持, 市地级, 2007-07--2012-12 ( 3 ) 猪牛羊哺乳动物人工选择下的进化模式和机制, 主持, 国家级, 2013-01--2017-08 ( 4 ) 家猪经济性状基因的规模化发掘, 主持, 国家级, 2009-06--2011-05 ( 5 ) 云南省健康人群肠道微生物多样性研究, 主持, 省级, 2010-01--2013-12 ( 6 ) 牦牛肠道微生物组高原适应的基因组学机制, 主持, 省级, 2013-10--2017-12 ( 7 ) 青藏高原物种形成分化与适应机制, 主持, 部委级, 2013-01--2015-12 ( 8 ) 动物复杂性状的进化解析与调控, 主持, 部委级, 2014-06--2019-05 ( 9 ) 哺乳动物适应性进化的遗传学机制, 主持, 国家级, 2014-01--2017-12 ( 10 ) 基因组中新遗传结构的起源与动物的适应进化, 主持, 国家级, 2014-01--2016-12 ( 11 ) 基因组中新遗传结构的起源与动物的适应进化, 主持, 国家级, 2017-01--2019-12 ( 12 ) 凸颅鼢鼠属快速物种形成及种间基因交流的基因组机制研究, 主持, 国家级, 2018-01--2019-12 ( 13 ) 第二次青藏高原综合考察, 主持, 国家级, 2019-01--2023-12 参与会议 (1)Differences in Genomic Adaptive Strategies to Hypoxia in Plateau Pika and Plateau Zokor 2013-07-12 (2)Different mechanisms for highaltiude adaptation to hypoxia: Genomics or the Highaltitude Yak and the Highealtitude- Subterranean Zokor in the Qinghai-Tibet plateau 2013-01-13 (3)Extraordinary diversity of chemosensory receptor gene repertoire among vertebrates 2008-05-27

近期论文

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(1) CDKN2B deletion is essential for pancreatic cancer development instead of unmeaningful co-deletion due to juxtaposition to CDKN2A, Oncogene, 2018, 通讯作者 (2) Genomic and functional evidence reveals molecular insights into the origin of echolocation in whales., Science Advances, 2018, 通讯作者 (3) Functional Effects of a Retained Ancestral Polymorphism in Prestin, Molecular Biology and Evolution, 2017, 通讯作者 (4) Convergent Evolution of Rumen Microbiomes in High-altitude Mammals, Current Biology, 2016, 通讯作者 (5) Independent Birth of a Novel TRIMCyp in Tupaia belangeri with a Divergent Function from Its Paralog TRIM5, Molecular Biology and Evolution, 2014, 通讯作者 (6) Spatial heterogeneity and co-occurrence patterns of human mucosal-associated intestinal microbiota, The ISME journal, 2014, 通讯作者 (7) Repeated Functional Convergent Effects of NaV1.7 on Acid Insensitivity in Hibernating Mammals(in press), Proceedings of the Royal Society B: Biological Sciences, 2014, 通讯作者 (8) Parallel sites implicate functional convergence of the hearing gene prestin among echolocating mammals, Molecular biology and evolution, 2014, 通讯作者 (9) The complete mitochondrial genome of Japanese sandeel Ammodytes personatus (Perciformes, Ammodytidae): Rare structure in control region compared, Mitochondrial DNA, 2013, 通讯作者 (10) Large-Scale Survey of Gut Microbiota Associated With MHE Via 16S rRNA-Based Pyrosequencing, AMERICAN JOURNAL OF GASTROENTEROLOGY , 2013, 通讯作者 (11) Gut microbiota dysbiosis and bacterial community assembly associated with cholesterol gallstones in large-scale study, BMC GENOMICS , 2013, 通讯作者 (12) Hearing Aid for Vertebrates via Multiple Episodic Adaptive Events on Prestin Genes, MOLECULAR BIOLOGY AND EVOLUTION, 2012, 通讯作者 (13) The yak genome and adaptation to life at high altitude , NATURE GENETICS, 2012, 通讯作者 (14) Parallel Evolution of KCNQ4 in Echolocating Bats, PLOS ONE, 2011, 通讯作者 (15) Phylogenomic reconstruction of lactic acid bacteria: an update, BMC Evolutionary Biology, 2011, 通讯作者 (16) Molecular and evolutionary analyses of formyl peptide receptors suggest the absence of VNO-specific FPRs in primates, J.Genet.Genomics, 2010, 通讯作者 (17) Comparative genomic analysis reveals more functional nasal chemoreceptors in nocturnal mammals than in diurnal mammals, Chinese Science Bulletin , 2010, 通讯作者 (18) More Functional V1R Genes Occur in Nest-Living and Nocturnal Terricolous Mammals, Genome Biology and Evolution , 2010, 通讯作者 (19) Artificial selection on Melanocortin receptor 1 (MC1R) gene in Chinese domestic pigs during the early domestication., Heredity, 2010, 通讯作者 (20) The hearing gene Prestin unites echolocating bats and whales, Current Biology, 2010, 第 2 作者 (21) Latest advances on the studies of function and evolution of bitter taste receptor gene (T2R) family, Chinese Science Bulletin, 2009, 通讯作者 (22) Relaxation of selective constraints on avian mitochondrial DNA following the degeneration of flight ability, Genome Research, 2009, 通讯作者 (23) Large Gene Family Expansions and Adaptive Evolution for Odorant and Gustatory Receptors in the Pea Aphid, Acyrthosiphon pisum, Mol. Biol. Evol, 2009, 第 2 作者 (24) Comparative genomic analysis identifies an evolutionary shift of vomeronasal receptor gene repertoires in the vertebrate transition from water to land, Genome Research, 2007, 第 1 作者 (25) Evolutionary dynamics of the ABCA-chr17q24 cluster genes in vertebrates, Genomics, 2007, 第 2 作者 (26) Did brain-specific genes evolve faster in humans than in chimpanzees, Trends in Genetics, 2007, 第 1 作者 (27) Largest vertebrate vomeronasal type 1 receptor (V1R) gene repertoire in the semi-aquatic platypus, Mol. Biol. Evol, 2007, 第 3 作者 (28) More genes underwent positive selection in chimpanzee evolution than in human evolution, Proc Natl Acad Sci, 2007, 第 2 作者 (29) Evolutionary implications of Avian Infectious Bronchitis Virus (AIBV) analysis, Cell Research, 2006, 第 2 作者 (30) Contrasting modes of evolution between vertebrate sweet/umami receptor genes and bitter receptor genes, Mol Biol Evol, 2006, 第 2 作者 (31) Independent origin of the growth hormone gene family in New World monkeys and Old World monkeys/hominoids, J Mol Endocrinol, 2006, 第 3 作者 (32) Composition and evolution of the V2R vomeronasal receptor gene repertoire in mice and rats, Genomics, 2005, 第 1 作者 (33) Adaptive molecular evolution of vomeronasal receptor 1 gene family in rodents, J Mol Evol, 2005, 第 1 作者 (34) Dramatic variation of the vomeronasal pheromone receptor gene repertoire among five orders of placental and marsupial mammals, Proc Natl Acad Sci, 2005, 第 1 作者

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