张雪梅 - 复旦大学

个人简介

教育经历 1995 - 2000，复旦大学，药理学，博士 1990 - 1995，上海医科大学，药理学，学士工作经历 2014 – 至今复旦大学，药学院，教授 2005 – 2014 复旦大学，药学院，副研究员 2000 – 2005 约翰霍普金斯大学博士后

研究领域

代谢药理学非兴奋性细胞离子通道，转运体作用及其信号调控机制体内外药理活性评价

近期论文

查看导师新发文章（温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

Wang Y, Tao J, Wang M, Yang L, Ning F, Xin H, Xu X, Cai H, Zhang W*, Yu K*, Zhang X*. Mechanism of Regulation of Big-Conductance Ca2+-Activated K+ Channels by mTOR Complex 2 in Podocytes. Front physiology 2019;10(167):1-13 Wang Q, Wu ZL, Yuan X, Dong HY, Xu X, Xin H, Wang YH, Zhang JB, Chen L, Li HL*, Zhang XM*, Zhang WD*. Bilobetin induces kidney injury by influencing cGMP-mediated AQP-2 trafficking and podocyte cell cycle arrest. Phytomedicine. 2019;64:153073 Ning F, Xin H, Liu J, Lv C, Xin X, Wang M, Wang Y, Zhang W*, Zhang X*. Structure and function of USP5: Insight into physiological and pathophysiological roles. Pharmacol Res. 2019:104557 Wang Y, Guo Q, Hei H, Tao J, Zhou Y, Dong J, Xin H, Cai H, Gao J, Yu K, Reilly S, Yin P, Zhang X*. BK ablation attenuates osteoblast bone formation via integrin pathway. Cell Death Dis. 2019;10(10):738 Wang L, Hou J, Wang J, Zhu Z, Zhang W*, Zhang X*, Shen H*, Wang XD*. Regulatory roles of HSPA6 in Actinidia chinensis Planch. root extract (acRoots)‐inhibited lung cancer proliferation. Clin Transl Med. 2020 Han B, Xie W, Zhang Y, Zhou S, Yang J, Wang R, Sun Y, Wang X, Xu J, Chen D, Wang Y, Lu J,Ning F, Shen F, Liu M, Cai H, Xin H*, Lu W* and Zhang X*.The influx/efflux mechanisms of DCDX across the blood–brain barrier and its therapeutic value in treating glioma. Journal of Controlled Release. 2020 Ning FL, Tao J, Li DD, Tian LL, Wang ML, Reilly S, Liu C, Cai H, Xin H*, Zhang XM*. Activating BK channels ameliorates vascular smooth muscle calcification through Akt signalingActa Pharmacol Sin. 2021 Jun 23. Jiang L, Yang Q, Gao J, Yang J, He J, Xin H*, Zhang X*. BK Channel Deficiency in Osteoblasts Reduces Bone Formation via the Wnt/β-Catenin Pathway. Mol cells.2021.0004. Fu M, Zhu Y, Zhang J, Wu W, Sun Y, Zhang X*, Tao J*, Li Z*MicroRNA-221-3p Suppresses the Microglia Activation and Seizures by Inhibiting of HIF-1α in Valproic Acid-Resistant Epilepsy. Front Pharmacol. 2021 12:714556 Wang Y, Wang M, Ren D , Ning F, Tao J, Xie W, Eaton D, Jiang G, Farris A, Xin H, Cai H*, Zhang X*. A Novel Role of BK Channel Activity in Preventing Development of Renal Fibrosis. Kidney Int 2021 Wang M, Zeng F, Ning F, Wang Y, Zhou S, He J, Li C, Wang C, Sun X, Zhang D, Xiao J, Hu P, Reilly S, Xin H*, Xu X*, Zhang X*. Ceria nanoparticles ameliorates renal fibrosis by modulating the balance between oxidative phosphorylation and aerobic glycolysis. Journal of Nanobiotechnology 2022 Jan 4;20(1):3. Cui X, Jia H, Xin H, Zhang L, Chen S, Xia S, Li X, Xu W, Chen X, Feng Y, Wei X, Yu H, Wang Y, Zhan Y, Zhu X*, Zhang X*. A Novel Bispecific Antibody Targeting PD-L1 and VEGF with Combined Anti-Tumor Activities. Front immunology, 2021 Dec 2;12:778978.

学术兼职

教育部高等学校药学类专业教学指导委员会委员和(大)药学专业分委会副主任委员教育部高等教育教学评估中心药学类专业认证工作委员会委员中国药理学会理事及肾脏药理专业委员会常务委员上海市药学会常务理事及老年药学专业委员会主任委员上海市药理学会理事及教学专业委员会主任委员人民卫生出版社全国高等学校药学类专业第六届教材评审委员会委员