力弘 - 复旦大学

个人简介

教育经历 2002/09 -2006/06，复旦大学药学院药理教研室，博士 1992/09-1995/06，上海医科大学药学院药理教研室，硕士 1984/09-1989/06，上海医科大学药学院药理教研室，本科 2002．12-至今复旦大学药学院药理教研室，副教授/硕士生导师，研究工作经历 2000/09-2001/06，国家教委基金公派，瑞典LUND 大学Section for Medical Inflammation Research进修分子生物学和免疫学 1997/12-2002/12，上海医科大学药学院药理教研室，讲师 1995/12-1997/12，上海医科大学药学院药理教研室，助教 1990/09-1991/06，南京军区总院药剂科，进修临床药理学 1989/09-1992/09，厦门中山医院药剂科，临床药师

研究领域

主要从事中草药及其活性成分的抗炎和免疫调节作用的药效和作用机制研究。进采用整体和离体方法筛选中药活性成分，建立了多种免疫和炎症相关疾病模型（自身免疫病模型、免疫低下动物模型，过敏性动物模型，糖尿病动物模型），在相关防治药物的筛选、药效和机制研究方面具有丰富经验

近期论文

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Pan LY, Weng HB, Li H, Liu ZZ, Xu YY, Zhou CJ, Lu XX, Su XY, Zhang YY , Chen DF. Therapeutic Effects of Bupleurum Polysaccharides in Streptozotocin Induced Diabetic Mice. 2015 Plos One，in press. SCI, IF=2 Jiang YW, Li H*, Zhang YY, Li W, Jiang YF, Ou YY, Chen DF*. Beneficial Effect of Bupleurum Polysaccharides on Autoimmune-Prone MRL-lpr Mice. Clinical & developmental immunology 2012,2012:842928. doi:10.1155/2012/842928 SCI, IF=1.838 Li Wen, Xie JY, Li H*, Zhang YY, Cao J, Cheng ZH, Chen DF. Viola yedoensis liposoluble fraction ameliorates lipopolysaccharide-induced acute lung injury in mice. The American Journal of Chinese Medicine. 2012. Vol. 40, No. 5, 1007–1018 SCI, IF=1.979 Xie JY, Di HY, Li H* Cheng XQ, Zhang YY, Chen DF*. Bupleurum chinense DC polysaccharides attenuates lipopolysaccharide-induced acute lung injury in mice. Phytomedicine 2012,19,130-137. SCI, IF=3.268 Cheng XQ, Song LJ, Li H*, Di HY, Xie JY, Zhang YY, Chen DF*.Beneficial effect of the polysaccharides from Bupleurum smithii var. parvifolium on “Two-Hit” acute lung injury in rats. Inflammation 2012, 35（5）；1715-1722（DOI: 10.1007/s10753-012-9489-7）IF=1.747 Jiang L, Wang Z, Zhu HW, Di HY, Li H*, Zhang YY, Chen DF. Beneficial effect of Eucommia polysaccharides on Systemic lupus erythematosus - like syndrome induced by Campylobacter jejuni in BALB/cmice. Inflammation 2011, 402-411，DOI:10.1007/s 10753-010 -9247-7. SCI, IF=1.747 Cheng XQ, Li H*, Yue XL, Xie JY, Zhang YY, Di HY, Chen DF. Macrophage immunomodulatory activity of the polysaccharides from the roots of Bupleurum smithii var. parvifolium. Journal of Ethnopharmacology 2010,130: 363-368. SCI,IF=2.466 Huang H, Li H#, Zhou P, Ju DW. Protective effects of recombinant human granulocyte macrophage colony stimulating factor on H1N1 influenza virus-induced pneumonia in mice. Cytokine 2010, 51: 151-157.共同第一 SCI, IF=3.537 Wang Z, Li H*, Xu H, Yue XL, Cheng XQ, Hou WJ, Zhang YY , Chen DF*. Beneficial effect of Bupleurum polysaccahrides on autoimmune disease induced by Campylobacter jejuni in BALB/c mice, Ethnopharmacology，2009；124:481-487. SCI, IF=2.322 Li H; Zhang YY, HuangXY, SunYN, JiaYF, Li D. Beneficial effect of tripterine on systemic lupus erythematosus induced by active chromatin in BALB/c mice. 2005；Eur J Pharmacol,512（11）：231-237 SCI, IF=2.477 Li H; Zhang YY; Tan HW; Jia YF; Li D. Therapeutic effect of tripterine on adjuvant arthritis in rats. Journal of Ethnopharmacology,2008, 118，479-484. SCI,IF=2.260 Li H, Zhang YY, Sun YN, Huang XY, Jia YF, Li D. Induction of systemic lupus erythematosus (SLE) syndrome in BALB/c mice by immunization with active chromatin. Acta Pharmacologica Sinica. 2004；25（6）：807－811. SCI,IF=1.125