朱依谆 - 复旦大学

个人简介

朱依谆教授于1995年获得德国海德堡大学博士学位, 现任澳门科技大学药学院院长、讲座教授和复旦大学讲座教授。曾任复旦大学药学院院长，为国家杰出青年基金获得者、国家重大科学研究计划（973）首席科学家、国家重大新药创制大平台负责人、上海市优秀学科带头人和上海市白玉兰纪念奖获得者。目前担任多家国际学刊的编委，先后获得16项新药发明专利的授权，一个原研候选新药以1.5亿元人民币进行成果转让，目前正在中美两国开展临床试验。

近期论文

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Zhu YZ*, ZJ Wang, PY Ho, YY Loke, YC Zhu, SH Huang, CS Tan, M Whiteman, J Lu, PK Moore. 它引98次)Hydrogen sulfide and its possible roles in myocardial ischemia in experimental rats. J Applied Physiology 102(1):261-268 2007 (IF: 3.75, YZ Zhu*, SH Huang, BKH Tan, J Sun, M Whiteman YC Zhu. Antioxidants in Chinese herbal medicines: a biochemical perspective. Nat. Prod. Rep.2004, 21 (4), 478 – 489. (IF 9.2) H. Wang, P. T.-H. Wong, J. Spiess and Y.Z. Zhu*. Role of Cholecystokinin-2 (CCK2) receptor and its molecular mechanisms in anxiety behaviors of experimental rats. Neurosci. & Biobeh. Rev., 29: 1361-73, 2005. (IF 7.8) P. Rose, M. Whiteman, P.K. Moore and Y.Z. Zhu*. Bioactive S-alk(en)yl cysteine sulfoxides metabolites in the genus Allium: The Chemistry of potential therapeutic agents. Nat. Prod. Rep.2005: 22, 351 - 368. (IF 9.2) H Lim, YZ Zhu*. Role of transforming growth factor-beta in the progression of heart failure. Cell. Mol. Life Sci. 63(22):2584-96, 2006. (IF 6.6) YL Fu, WL Chen, PK Moore, YZ Zhu*. Cardioprotective effects of Nitric Oxide-Aspirin in myocardial ischemia-reperfused rats. Am J Physiol Heart Circ Physiol.293(3):H1545-52. (IF 3.7) SC Chuah, YZ Zhu*. S-allylcysteine mediates cardioprotection in an acute myocardial infarction rat model via a hydrogen sulphide mediated pathway. Am J Physiol Heart Circ Physiol. . 293(5):H2693-701. (IF 3.7) T Sherrin, C Todorovic, T Zeyda, CH Tan, PWT Hon, YZ Zhu* and J Spiess. Chronic stimulation of corticotropin-releasing factor receptor 1 enhances the anxiogenic response of the cholecystokinin system. Molecular Psychiatry 2009, 14(3): 291-307. (IF 13.7) Loh KP, Qi J, Tan BK, Zhu YZ*. Leonurine (4-guanidino-n-butyl Syringate) Protects the Middle Cerebral Artery Occluded Rats through Antioxidant effect and Regulation of Mitochondrial Function. Stroke 2010 2010 Nov;41(11):2661-8. (IF: 7.05) Gong QH, Wang Q, Pan LL, Liu XH, Xin H, Zhu YZ*. S-Propargyl-cysteine, a novel hydrogen sulfide-modulated agent, attenuates lipopolysaccharide-induced spatial learning and memory impairment: Involvement of TNF signaling and NF-κB pathway in rats. Brain Behav Immun. 2011 Jan;25(1):110-9. Epub 2010 Sep 7. (IF 5.1) Q Wang , Zhu YZ*. Protective effects of cysteine analogues on acute myocardial ischemia: Novel modulators of endogenous H2S production. Antioxidant Redox Signaling, 2010 May 15;12(10):1155-65. (IF 8.2). Pan LL, Liu XH, Zheng HM, Yang HB, Gong QH, Zhu YZ*. propargyl-cysteine, novel hydrogen sulfide-modulated agent, attenuated tumor necrosis factor-alpha-induced inflammatory signaling and dysfunction in endothelial cells. Int J Cardiol 2012; 55(2):327-32. (IF 7.1) Pan LL, Liu XH, Gong QH, Yang HB, Zhu YZ*. Role of Cystathionine γ-Lyase/Hydrogen Sulfide Pathway in Cardiovascular Disease: A Novel Therapeutic Strategy? Antioxid Redox Signal. 2012 Jul 1;17(1):106-18. (IF 8.2) Zhang Y, Guo W, Wen Y, Xiong Q, Liu H, Wu J, Zou Y, Zhu YZ*. SCM-198 attenuates early atherosclerotic lesion in hypercholesterolemic rabbits via modulation of inflammation and oxidative stress pathways. Atherosclerosis 2012 in press. (IF 4.08) Liu XH, Pan LL, Deng HY, Xiong QH, Wu D, Huang GY, Gong QH, Zhu YZ*. Leonurine (SCM-198) attenuates myocardial fibrotic response via inhibition of NAPDH oxidase 4. Free Radical Biology & Medicine in press 2012. (IF 5.4)