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研究领域

Interaction of cells with nanostructured materials and surfaces Professor Alan Rowan is performing his research at the interface of chemistry and biology with seminal and pioneering work on processive catalysis and functional self-assembly. His latest scientific achievement has been the development of the first truly biomimetic hydrogel which mimics the mechanic and functional properties of the extracellular membrane. This recent discovery has further established Professor Rowan as a truly innovative scientist, working toward understanding at the molecular level the functional of hierarchical materials and catalysis.

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Biomimetic networks with enhanced photodynamic antimicrobial activity from conjugated polythiophene/polyisocyanide hybrid hydrogels Yuan, Hongbo, Zhan, Yong, Rowan, Alan E., Xing, Chengfen and Kouwer, Paul H. J. (2020) Biomimetic networks with enhanced photodynamic antimicrobial activity from conjugated polythiophene/polyisocyanide hybrid hydrogels. Angewandte Chemie, . doi:10.1002/anie.201910979 Organothiol monolayer formation directly on muscovite mica de Poel, Wester, Brugman, Sander J. T., van de Ven, Kim H. A., Gasseling, Anouk, de Lange, Jordi, Townsend, Eleanor R., Engwerda, Anthonius H. J., Jankowski, Maciej, Blijlevens, Melian A. R., Werkhoven, Ben L., Drnec, Jakub, Carlà, Francesco, Felici, Roberto, Tuladhar, Aashish, Adhikari, Narendra M., De Yoreo, James J., Elemans, Johannes A. A. W., van Enckevort, Willem J. P., Rowan, Alan E. and Vlieg, Elias (2019) Organothiol monolayer formation directly on muscovite mica. Angewandte Chemie International Edition, . doi:10.1002/anie.201913327 Erratum: Highly Selective Reduction of Carbon Dioxide to Methane on Novel Mesoporous Rh Catalysts (ACS Appl. Mater. Interfaces (2018) 10:30 (24963-24968) DOI: 10.1021/acsami.8b06977) Arandiyan, Hamidreza, Kani, Kenya, Wang, Yuan, Jiang, Bo, Kim, Jeonghun, Yoshino, Masahiro, Rezaei, Mehran, Rowan, Alan E., Dai, Hongxing and Yamauchi, Yusuke (2019) Erratum: Highly Selective Reduction of Carbon Dioxide to Methane on Novel Mesoporous Rh Catalysts (ACS Appl. Mater. Interfaces (2018) 10:30 (24963-24968) DOI: 10.1021/acsami.8b06977). ACS Applied Materials and Interfaces, 11 49: 46398-46398. doi:10.1021/acsami.9b18665 Molecular design strategies for electrochemical behavior of aromatic carbonyl compounds in organic and aqueous electrolytes Peng, Huiling, Yu, Qianchuan, Wang, Shengping, Kim, Jeonghun, Rowan, Alan E., Nanjundan, Ashok Kumar, Yamauchi, Yusuke and Yu, Jingxian (2019) Molecular design strategies for electrochemical behavior of aromatic carbonyl compounds in organic and aqueous electrolytes. Advanced Science, . doi:10.1002/advs.201900431 Synthetic semiflexible and bioactive brushes Voerman, Dion, Schluck, Marjolein, Weiden, Jorieke, Joosten, Ben, Eggermont, Loek J., van den Eijnde, Tuur, Ignacio, Bob, Cambi, Alessandra, Figdor, Carl G., Kouwer, Paul H. J., Verdoes, Martijn, Hammink, Roel and Rowan, Alan E. (2019) Synthetic semiflexible and bioactive brushes. Biomacromolecules, 20 7: 2587-2597. doi:10.1021/acs.biomac.9b00385 Monitoring 111In-labelled polyisocyanopeptide (PIC) hydrogel wound dressings in full-thickness wounds Op 't Veld, Roel C., Joosten, Lieke, van den Boomen, Onno I., Boerman, Otto C., Kouwer, Paul, Middelkoop, Esther, Rowan, Alan E., Jansen, John A., Walboomers, X. Frank and Wagener, Frank A. D. T. G. (2019) Monitoring 111In-labelled polyisocyanopeptide (PIC) hydrogel wound dressings in full-thickness wounds. Biomaterials Science, 7 7: 3041-3050. doi:10.1039/c9bm00661c A portable and efficient solar‐rechargeable battery with ultrafast photo‐charge/discharge rate Hu, Yuxiang, Bai, Yang, Luo, Bin, Wang, Songcan, Hu, Han, Chen, Peng, Lyu, Miaoqiang, Shapter, Joe, Rowan, Alan and Wang, Lianzhou (2019) A portable and efficient solar‐rechargeable battery with ultrafast photo‐charge/discharge rate. Advanced Energy Materials, . doi:10.1002/aenm.201900872 Epitaxial crystallization of insulin on an ordered 2D polymer template de Poel, Wester, Elemans, Johannes A. A. W., van Enckevort, Willem J. P., Rowan, Alan E. and Vlieg, Elias (2019) Epitaxial crystallization of insulin on an ordered 2D polymer template. Chemistry: A European Journal, 25 15: 3756-3760. doi:10.1002/chem.201805276 Synthetic extracellular matrices with nonlinear elasticity regulate cellular organization Liu, Kaizheng, Mihaila, Silvia M., Rowan, Alan, Oosterwijk, Egbert and Kouwer, Paul H. J. (2019) Synthetic extracellular matrices with nonlinear elasticity regulate cellular organization. Biomacromolecules, 20 2: 826-834. doi:10.1021/acs.biomac.8b01445 Cytoskeletal stiffening in synthetic hydrogels de Almeida, Paula, Jaspers, Maarten, Vaessen, Sarah, Tagit, Oya, Portale, Giuseppe, Rowan, Alan E. and Kouwer, Paul H. J. (2019) Cytoskeletal stiffening in synthetic hydrogels. Nature Communications, 10 1: 609. doi:10.1038/s41467-019-08569-4 Injectable biomimetic hydrogels as tools for efficient T Cell expansion and delivery Weiden, Jorieke, Voerman, Dion, Dölen, Yusuf, Das, Rajat K., Van Duffelen, Anne, Hammink, Roel, Eggermont, Loek J., Rowan, Alan E., Tel, Jurjen and Figdor, Carl G. (2018) Injectable biomimetic hydrogels as tools for efficient T Cell expansion and delivery. Frontiers in Immunology, 9 NOV: . doi:10.3389/fimmu.2018.02798 Tunable properties based on regioselectivity of 1,2,3-triazole units in axially chiral 2,2′-linked 1,1′-binaphthyl-based copolymers for ions and acid responsiveness Lauko, Ján, Kouwer, Paul H. J., Kasak, Peter and Rowan, Alan E. (2018) Tunable properties based on regioselectivity of 1,2,3-triazole units in axially chiral 2,2′-linked 1,1′-binaphthyl-based copolymers for ions and acid responsiveness. European Polymer Journal, 108 191-198. doi:10.1016/j.eurpolymj.2018.08.030 Self-assembly of porphyrin hexamers via bidentate metal-ligand coordination Lensen, Marga C., Nolte, Roeland J. M., Rowan, Alan E., Pyckhout-Hintzen, Wim, Feiters, Martin C. and Elemans, Johannes A. A. W. (2018) Self-assembly of porphyrin hexamers via bidentate metal-ligand coordination. Dalton Transactions, 47 40: 14277-14287. doi:10.1039/c8dt01572d Thermosensitive biomimetic polyisocyanopeptide hydrogels may facilitate wound repair op ‘t Veld, Roel C., van den Boomen, Onno I., Lundvig, Ditte M.S., Bronkhorst, Ewald M., Kouwer, Paul H. J., Jansen, John A., Middelkoop, Esther, Von den Hoff, Johannes W., Rowan, Alan E. and Wagener, Frank A. D. T. G. (2018) Thermosensitive biomimetic polyisocyanopeptide hydrogels may facilitate wound repair. Biomaterials, 181 392-401. doi:10.1016/j.biomaterials.2018.07.038 Mesoporous metallic iridium nanosheets Jiang, Bo, Guo, Yanna, Kim, Jeonghun, Whitten, Andrew E., Wood, Kathleen, Kani, Kenya, Rowan, Alan E., Henzie, Joel and Yamauchi, Yusuke (2018) Mesoporous metallic iridium nanosheets. Journal of the American Chemical Society, 140 39: 12434-12441. doi:10.1021/jacs.8b05206 Catalytic single-chain polymeric nanoparticles at work: from ensemble towards single-particle kinetics Liu, Yiliu, Turunen, Petri, de Waal, Bas F. M., Blank, Kerstin G., Rowan, Alan E., Palmans, Anja R. A. and Meijer, E. W. (2018) Catalytic single-chain polymeric nanoparticles at work: from ensemble towards single-particle kinetics. Molecular Systems Design & Engineering, 3 4: 609-618. doi:10.1039/c8me00017d Highly selective reduction of carbon dioxide to methane on novel mesoporous Rh catalysts Arandiyan, Hamidreza, Kani, Kenya, Wang, Yuan, Jiang, Bo, Kim, Jeonghun, Yoshino, Masahiro, Rezaei, Mehran, Rowan, Alan E., Dai, Hongxing and Yamauchi, Yusuke (2018) Highly selective reduction of carbon dioxide to methane on novel mesoporous Rh catalysts. ACS Applied Materials and Interfaces, . doi:10.1021/acsami.8b06977 Materials nanoarchitectonics using 2D layered materials: recent developments in the intercalation process Sangian, Danial, Ide, Yusuke, Bando, Yoshio, Rowan, Alan E. and Yamauchi, Yusuke (2018) Materials nanoarchitectonics using 2D layered materials: recent developments in the intercalation process. Small , e1800551. doi:10.1002/smll.201800551 Crosslinking of fibrous hydrogels Schoenmakers, Daniël C., Rowan, Alan E. and Kouwer, Paul H. J. (2018) Crosslinking of fibrous hydrogels. Nature Communications, 9 1: 2172. doi:10.1038/s41467-018-04508-x 3D printing of Thermoresponsive Polyisocyanide (PIC) hydrogels as bioink and fugitive material for tissue engineering Celikkin, Nehar, Padial, Joan Simo, Costantini, Marco, Hendrikse, Hans, Cohn, Rebecca, Wilson, Christopher J., Rowan, Alan Edward and Swieszkowski, Wojciech (2018) 3D printing of Thermoresponsive Polyisocyanide (PIC) hydrogels as bioink and fugitive material for tissue engineering. Polymers, 10 5: 555. doi:10.3390/polym10050555 Deciphering Design Principles of Förster Resonance Energy Transfer-Based Protease Substrates: Thermolysin-Like Protease from Geobacillus stearothermophilus as a Test Case Ripp, Sophie, Turunen, Petri, Minot, Ethan D., Rowan, Alan E. and Blank, Kerstin G. (2018) Deciphering Design Principles of Förster Resonance Energy Transfer-Based Protease Substrates: Thermolysin-Like Protease from Geobacillus stearothermophilus as a Test Case. ACS Omega, 3 4: 4148-4156. doi:10.1021/acsomega.7b02084

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