张奇志 - 复旦大学

个人简介

教育经历 1988.09 – 1992.07 华西医科大学药学院药物化学专业，学士 1994.09 – 1997.07 华西医科大学药学院药剂学，硕士 1999.09 – 2003.07 复旦大学药学院药剂学，博士工作经历 1992.07 – 1994.08 重庆制药六厂药物研究所，助理工程师 2008.07 – 2009.07 香港全球药物科技有限公司，Scientist 1997.07 – 2005.05 复旦大学药学院，讲师 2005.05 – 2012.12 复旦大学药学院，副教授 2012.12- 至今复旦大学药学院，教授获奖及荣誉 2011.01 教育部自然科学一等奖（排名第三） 2010.11 上海市自然科学二等奖（排名第三） 2010.08 中国药学会科学技术二等奖（排名第四）

研究领域

纳米药物脑靶向递释系统鼻腔给药的脑内递药特性研究药物新剂型与新制剂的研究开发

近期论文

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Wan X, Zheng X, Pang X, Zhang Z, Jing T, Xu W, Zhang QZ*. The potential use of lapatinib-loaded human serum albumin nanoparticles in the treatment of triple-negative breast cancer.Int J Pharm. 2015, 484(1-2):16-28. Liu QF, Zheng XY, Zhang C, Shao XY, Zhang X, Zhang QZ*, Jiang XG. Antigen-conjugated N-trimethylaminoethylmethacrylate chitosan nanoparticles induce strong immune responses after nasal administration. Pharm Res, 2015, 32(1): 22-36 Zhang C, Zheng XY, Wan X, Shao XY, Liu QF, Zhang ZM, Zhang QZ*.The potential use of H102 peptide-loaded dual-functional nanoparticles in the treatment of Alzheimer's disease.J Control Release, 2014, 192: 317-324 Zhang C, Wan X, Zheng XY, Shao XY, Liu QF, Zhang QZ*, Qian Y. Dual-functional nanoparticles targeting amyloid plaques in the brains of Alzheimer's disease mice.Biomaterials, 2014, 35: 456-465 Qian Y, Zha Y, Feng B, Pang ZQ, Zhang B, Sun XY, Ren JF, Zhang C, Shao XY, Zhang QZ*, Jiang XG. PEGylated poly(2-(dimethylamino) ethyl methacrylate)/DNA polyplex micelles decorated with phage-displayed TGN peptide for brain-targeted gene delivery. Biomaterials, 2013, 34: 2117~2129 Gao HL, Qian J, Yang Z, Pang ZQ, Xi ZJ, Cao SL, Wang YC, Pan SQ, Zhang S, Wang W, Jiang XG, Zhang QZ*. Whole-cell SELEX aptamer-functionalised poly(ethyleneglycol)- poly(ε-caprolactone) nanoparticles for enhanced targeted glioblastoma therapy. Biomaterials, 2012, 33: 6264~6272. ao HL, Qian J, Cao SL, Yang Z, Pang ZQ, Pan SQ, Fan L, Xi ZJ, Jiang XG, Zhang QZ*. Precise glioma targeting of and penetration by aptamer and peptide dual-functioned nanoparticles. Biomaterials, 2012, 33: 5115~5123 Liu QF, Shen YH, Chen J, Gao XL, Feng CC, Wang L, Zhang QZ*, Jiang XG. Nose-to-Brain Transport Pathways of Wheat Germ Agglutinin Conjugated PEG-PLA Nanoparticles.Pharm Res. 2012; 29(2): 546-558 Feng CC, Zhang C, Shao XY, Liu QF, Qian Y, Feng L, Chen J, Zha Y, Zhang QZ*, Jiang XG. Enhancement of nose-to-brain delivery of basic fibroblast growth factor for improving rat memory impairments induced by co-injection of -amyloid and ibotenic acid into the bilateral hippocampus.Int J Pharm,2012, 423: 226-234. Liu QF, Shao XY, Chen J, Shen YH, Feng CC, Gao XL, Zhao Y, Li JW, Zhang QZ*, Jiang XG. In vivo toxicity and immunogenicity of wheat germ agglutinin conjugated poly(ethylene glycol)-poly(lactic acid) nanoparticles for intranasal delivery to the brain. Toxicol Appl Pharm, 2011, 251: 79-84.

学术兼职

2011.12 – 现在上海市药学会药剂专业委员会，委员 2013.07 – 现在中国药学杂志,编委