个人简介
教育经历
1998.09 – 2003.06 中国药科大学中药学院,生药学博士
1994.09 – 1998.06 中国药科大学中药学院,中药分析学学士
工作经历
2018.12 -- 今 复旦大学药学院,教授
2009.01 – 2018.12 复旦大学药学院,副研究员
2005.10 – 2008.08 美国马里兰大学(University of Maryland at College Park),博士后
2003.07 – 2005.09 中科院上海有机化学研究所,博士后
获奖及荣誉
2011.01 教育部自然科学二等奖-麦冬类中药的系统研究(第三完成人)
研究领域
中草药的药效物质基础及质量控制研究
小分子天然产物的微生物转化研究
近期论文
查看导师新发文章
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Fan Xiaofan, Li Yingzhe, Wu Tao, Cheng Zhihong*. Screening and identification of neuraminidase inhibitors from Baphicacanthus cusia by a combination of affinity ultrafiltration, HPLC-MS/MS, molecular docking, and fluorescent techniques. Journal of Chromatography B, 2023, 1231: 123924;
Zang Yichao, Miao Yu, Wu Tao*, Cheng Zhihong*. Development of a thin-layer chromatography bioautographic assay for neuraminidase inhibitors hyphenated with electrostatic field induced spray ionisation-mass spectrometry for identification of active Isatis indigotica root compounds. Journal of Chromatography A, 2021, 1638: 461597;
Guo Qihui, Li Zeyun, Shen Lulu, Xiao Ying*, Cheng Zhihong*. Quantitative 1H nuclear magnetic resonance (qHNMR) methods for accurate purity determination of glucosinolates isolated from Isatis indigotica roots. Phytochemical Analysis, 2021, 32: 104-111;
Ding Pei-Lan, He Chang-Ming, Cheng Zhi-Hong*, Chen Dao-Feng*. Flavonoids rather than alkaloids as the diagnostic constituents to distinguish Sophorae Flavescentis Radix from Sophorae Tonkinensis Radix et Rhizoma: an HPLC fingerprint study. Chinese Journal of Natural Medicines, 2018, 16(12): 951-960;
Qin Yan, Gao Boyan, Shi Haiming, Cao Jie, Yin Chengle, Lu Weiying, Yu Liangli, Cheng Zhihong*. Characterization of flavonol mono-, di-, tri- and tetra-O-glycosides by ultra-performance liquid chromatography-electrospray ionization-quadrupole time-of-flight mass spectrometry and its application for identification of flavonol glycosides in Viola tianschanica. Journal of Pharmaceutical and Biomedical Analysis, 2017, 142: 113-124;
Zhang Lei, Shi Jiyao, Tang Jihe, Cheng Zhihong*, Lu Xiaohui, Kong Yao, Wu Tao*. Direct coupling of thin-layer chromatography-bioautography with electrostatic field induced spray ionization-mass spectrometry for separation and identification of lipase inhibitors in lotus leaves. Analytica Chimica Acta, 2017, 967: 52-58;
Wu Yiqing, Yin Chengle, Cao Yue, Liu Xin, Yu Jinxiang, Zhang Jian, Yu Boyang, Cheng Zhihong*. Regioselective hydroxylation of lathyrane diterpenoids biocatalyzed by microorganisms and its application in integrated synthesis. Journal of Molecular Catalysis B: Enzymatic, 2016, 133: S352-S359;
Du Dongsheng, Lu Yan, Cheng Zhihong*, Chen Daofeng*. Structure characterization of two novel polysaccharides isolated from the spikes of Prunella vulgaris and their anticomplement activities. Journal of Ethnopharmacology, 2016, 193: 345-353;
Qin Yan, Pang Yingming, Cheng Zhihong*. Needle trap device as a new sampling and preconcentration approach for volatile organic compounds of herbal medicines and its application to the analysis of volatile components in Viola tianschanica. Phytochemical Analysis, 2016, 27(6): 364-374;
Yin Chengle, Zhou Jinge, Wu Yiqing, Cao Yue, Wu Tao, Zhang Shoude, Li Honglin, Cheng Zhihong*. Pterocarpans and triterpenoids from Gueldenstaedtia verna. Fitoterapia, 2015, 106: 46-54;
Cao Jie, Yin Chengle, Qin Yan, Cheng Zhihong*, Chen Daofeng. Approach to the study of flavone di-C-glycosides by high performance liquid chromatography-tandem ion trap mass spectrometry and its application to characterization of flavonoid composition in Viola yedoensis. Journal of Mass Spectrometry, 2014, 49: 1010-1024;
Xiao Guodong, Li Guowen, Chen Liang, Zhang Zijia, Yin Jun-Jie, Wu Tao*, Cheng Zhihong*, Xiaohui Wei, Zhengtao Wang.Isolation of antioxidants from Psoralea corylifolia fruits using high-speed counter-current chromatography guided by thin layer chromatography-antioxidant autographic assay. Journal of Chromatography A, 2010, 1217: 5470-5476;
Cheng Zhihong, Zhou Huiping, Luther Marla, Yin Junjie, Yu Liangli*. Effects of wheat antioxidants on oxygen diffusion-concentration products in liposomes and key genes for cholesterol biosynthesis and metabolism in primary rat hepatocytes. Journal of Agricultural & Food Chemistry, 2008, 56(13): 5033-5042;
Cheng Zhihong, Guo Yinlong*, Wang Haoyang, Chen Guoqiang. Qualitative and quantitative analysis of quaternary ammonium alkaloids from Rhizoma Corydalis by MALDI-FTMS coupled with a special precipitation reaction using Reinecke salt. Analytica Chimica Acta, 2006, 555: 269-277;
Cheng Zhihong, Yu Boyang*, Geoffrey A. Cordell, Qiu Shengxiang*. Biotransformation of quinovic acid glycosides by microbes: direct conversion of the ursane to the oleanane triterpene skeleton by Nocardia sp. NRRL 5646. Organic Letters, 2004, 6(18): 3163-3165.
学术兼职
2020.08-今 上海市药学会生药学专业委员会副主任委员
2020.12-今 上海市药学会第12届理事会理事
2020.06-今 中国康复医学会中药学与康复专业委员会第一届委员会常务委员
2015.12-今 SCI收录期刊《Current Analytical Chemistry》编委