李继扬 - 复旦大学

个人简介

教育经历 1986-1991 上海医科大学药学院药物化学专业本科 1993-1997 上海医科大学药学院药物化学专业硕士 2003-2008 复旦大学药学院药物化学专业博士工作经历 1991-1997 上海医科大学药学院助教 1997-2000 上海医科大学药学院讲师 2000-2009 复旦大学药学院讲师 2009-至今复旦大学药学院副教授 2012-2019 复旦大学枫林校区建设部部长 2013-2019 复旦大学枫林校区管委会副主任 2020-2021 复旦大学基建处副处长 2020-2021 复旦大学张江校区管委会副主任 2021-至今复旦大学枫林校区管委会主任 2022.07-至今九三学社上海市委员会委员获奖及荣誉 2005年获得上海市科学技术进步三等奖（排名第三）（上海市人民政府） 2005年获得上海药学科技进步奖二等奖（排名第三）（上海市药学会）

研究领域

微生物转化与微生物发酵的研究微生物次级代谢产物生物合成机制研究植物内生菌活性物质研究抗感染药物评价及抗感染天然活性物质研究

近期论文

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Wenxin Ding, Hao-Wei Chen, Mengran Wang, Miyang Wan, Jin-Feng Hu, Jiyang Li*. Three new eremophilane sesquiterpenes and one new related derivative from Nemania sp. HDF-Br-5, an endophytic fungus of the endangered conifer Pseudotsuga gaussenii Flous. Phytochemistry Letters. 2022, 49: 5-11. DOI: 10.1016 / J.PHYTOL. 2022. 02. 011 Yuan-Xing Zhu, Wenxin Ding, Jin-Feng Hu, Juan Xiong * ,Jiyang Li*. Beshanzuamide A, an unprecedented prenylated indole alkaloid produced by the endophytic Aspergillus sp. Y-2 from the critically endangered conifer Abies beshanzuensi. RSC Advances .2022, DOI：10.1039/D2RA01578A Miyang Wan, Cheng Peng, Wenxin Ding, Mengran Wang, Jinfeng Hu, Jiyang Li*. Calcium-phosphate combination enhances spinosad production in Saccharopolyspora spinosa via regulation of fatty acid metabolism. Applied Biochemistry and Biotechnology. 2022, DOI:10.1007/s12010-022-03799-7 Wei, T. Y., Zheng, Y., Wan, M., Yang, S., Tang, J., Wu, Y., Li, J., & Chen, S. X*. Analysis of FR901379 Biosynthetic Genes in Coleophoma empetri by Clustered Regularly Interspaced Short Palindromic Repeats/Cas9-Based Genomic Manipulation. ACS chemical biology, 2022, 17(8), 2130–2141. https://doi.org/10.1021/acschembio.2c00250 Wang, M., Gu, K., Ding, W., Wan, M., Zhao, W., Shi, H., & Li, J. *. Antifungal effect of a new photosensitizer derived from BODIPY on Candida albicans biofilms. Photodiagnosis and photodynamic therapy, 2022, 39, 102946. https://doi.org/10.1016/j.pdpdt.2022.102946 Guangyu Lin, Mei Hu, Rong Zhang, Yuanxing Zhu, Kedan Gu, Junping Bai, Jiyang Li*, Xiaochun Dong*, Weili Zhao*. Discovery of Meso-(meta-Pyridinium) BODIPY Photosensitizers: In Vitro and In Vivo Evaluations for Antimicrobial Photodynamic Therapy. J. Med. Chem., 2021, 64 (24): 18143-1815. Hang Shi*,Jiyang Li*, Cheng Peng, Hongying Sun*.The inhibitory activity of 5-aminolevulinic acid photodynamic therapy (ALA-PDT) on Candida albicans biofilms. Photodiagnosis and Photodynamic Therapy, 2021,4:102271. Yuan-Xing Zhu, Cheng Peng, Shui Yu ,Jin-Feng Hu, Jiyang Li*. Aflatoxins from the endophytic fungus Aspergillus sp. Y-2 isolated from the critically endangered conifer Abies beshanzuensi. Natural Product Research, 2021, 35: 3248-3253. Shui Yu, Yuan-Xing Zhu, Cheng Peng, Jiyang Li*. Two new sterol derivatives isolated from the endophytic fungus Aspergillus tubingensis YP-2. Natural Product Research, 2021, 35: 3277-3284. Cheng Peng, Duopeng An, WenXin Ding, Yuan-Xing Zhu, Li Ye, Jiyang Li*. Fungichromin production of Streptomyces sp. WP-1, an endophyte from Pinus dabeshanensis, and its antifungal activity against Fusarium oxysporum. Applied Microbiology and Biotechnology, 2020, 104: 10437–10449. Yuan-Xing Zhu, Cheng Peng, Wenxin Ding, Jin-Feng Hu, Jiyang Li*. Chromenopyridin A, a new N-methoxy-1-pyridone Alkaloid from the endophytic fungus Penicillium nothofagi P-6 isolated from the critically endangered conifer Abies beshanzuensi. Natural Product Research, 2020, 2: 1-7. Kedan Gu, Guangyu Lin, Yuanxing Zhu, Xin Ji, Jiyang Li*, Xiaochun Dong*, Weili Zhao*. Anchoring BODIPY photosensitizers enable pan-microbial photo-inactivation. Eur. J Med. Chem., 2020, 199: 112361