张倩 - 复旦大学

个人简介

教育经历 2000.09 – 2004.01复旦大学药学院，获理学博士学位 1996.09 – 1999.07上海医科大学药学院，获理学硕士学位 1989.09 – 1993.07沈阳药科大学，获理学学士工作经历 2015.02 - 2016.03美国堪萨斯大学药学院，访问学者 2008.05 – 2009.02奥地利维也纳大学，访问学者 1999.07 – 至今复旦大学药学院，讲师/副教授 1993.07 – 1996.09广东省汕头市沱滨药业有限公司，助理研究员

研究领域

分子靶标抗肿瘤药物/肿瘤诊断剂研究

近期论文

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Jiawei Zhang, Jingyi Liu, Kaimin Kong, Xingzhou Li*, Qian Zhang*. Structure–activity relationship studies of 5-(Pyridin-3-yl)-1H-indole-4,7-diones as indoleamine 2,3-dioxygenase 1 inhibitors. Results in chemistry, 2024, 7, 101285. Xiaoqian Hong, Qunxian Cheng, Minli Ruan , Baohua Yang , Jingyi Liu , Ling Xu*, Qian Zhang*. Determination of DNA Methyltransferase 1 in Cells Using a RG108-Fluorescein Conjugate to Monitor the Fluorescent Ratio with a Microplate Reader. Analytical Letters, 2023, 56(10), 1660-1674. Hanyi Tan, Yue Liu, Chaochao Gong, Jiawei Zhang, Jian Huang*, Qian Zhang*. Synthesis and evaluation of FAK inhibitors with a 5-fluoro-7H-pyrrolo [2,3-d]pyrimidine scaffold as anti-hepatocellular carcinoma agents. European Journal of Medicinal Chemistry, 2021, 223, 113670. Lei Xu, Lei Zhao, Jinjing Che, Qian Zhang*, Ruiyuan Cao*, Xingzhou Li* Identification of novel influenza polymerase PB2 inhibitors using virtual screening approach and molecular dynamics simulation analysis of active compounds. Bioorganic & Medicinal Chemistry, 2021, 52, 116515. Keli Zong, Lei Xu, Yuxin Hou, Qian Zhang*, Jinjing Che, Lei Zhao, Xingzhou Li,* Virtual Screening and Molecular Dynamics Simulation Study of Influenza Polymerase PB2 Inhibitors, Molecules, 2021, 26, 6944. Jiawei Zhang, Kaimin Kong, Xiangjun Li, Qian Zhang*. Kemp-type elimination of 1-arylsulfonyl-3-iodo1H-indazoles. Synthetic Communications, 2021, 51(15), 2365–2376. Minli Ruan, Qunxian Cheng, Chaochao Gong, Zhonglian Cao, Ling Xu*, Qian Zhang*. Development of a kind of RG108-Fluorescein conjugates for detection of DNA methyltransferase 1 (DNMT1) in living cells. Analytical Biochemistry, 2020, 607, 113823. Kaimin Kong, Jiawei Zhang, Binzhi Liu, Guangrong Meng, Qian Zhang*. Discovery of 5-(pyridin-3-yl)-1H-indole-4,7-diones as indoleamine 2,3-dioxygenase 1 (IDO1) inhibitors. Bioorganic & Medicinal Chemistry Letters, 2020, 30, 126901.