近期论文
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Publications:
1.ChangJ,WeiL,MiaoX,YuD,TanW,ZhangX,WuC,LinD.Twonovelvariantson13q22.1areassociatedwithriskofesophagealsquamouscellcarcinoma.CancerEpidemiologyBiomarkers&Prevention.2015;24(11):1774-80.
2.PeiN,CaoL,LiuY,WuJ,SongQ,ZhangZ,YuanJ,ZhangX.XAB2tagSNPscontributetonon-smallcelllungcancersusceptibilityinChinesepopulation.BMCCancer,2015;15:560
3.ZhaoL,ZhangZ,LinJ,CaoL,HeB,HanS,ZhangX.Complementreceptor1geneticvariantscontributetothesusceptibilitytogastriccancerinChinesepopulation.JournalofCancer,2015;6(6):525-530.
4.LiuY,BiY,LinJ,CaoL,HeB,ZhangZ,CuiY,ZhangX.TagSNPsofCFIcontributedtothesusceptibilityfornon-smallcelllungcancerinChinesepopulation.TumorBiology,2015;36(3):1955-1962.
5.SongQ，ZhangZ,LiuY,HanS,ZhangX.ThetagSNPrs10746463indecay-acceleratingfactorisassociatedwiththesusceptibilitytogastriccancer.MolecularImmunology,2015;63(2):473-478.
6.LinJ,HeB,CaoL,ZhangZ,LiuH,RaoJ,LiuY,ShaoS,WangG,ZhangX.CYP1A1Ile462Valpolymorphismandtheriskofnon-smallcelllungcancerinaChinesepopulation.Tumori,2014;100(5):547-552.
7.ZhangZ,YuD,LuJ,ZhaiK,CaoL,RaoJ,LiuY,ZhangX,GuoY.FunctionalgeneticvariantsofTNFSF15andtheirassociationwithgastricadenocarcinoma:Acase-controlstudy.PlosOne,2014;9(9):e108321.
8.LiuY,CaoL,ChangJ,LinJ,HeB,RaoJ,ZhangZ,ZhangX.XPF-673C>TpolymorphismeffectonthesusceptibilitytoesophagealcancerinChinesepopulation.PlosOne,2014;9(4):e94136.
9.YuX,RaoJ,LinJ,ZhangZ,CaoL,ZhangX*.TagSNPsincomplementreceptor-1contributetothesusceptibilitytonon-smallcelllungcancer.MolecularCancer,2014;13(1):56.
10.YangHP,LiuJF,RaoJ,ZhangXM,QianHL,NiuXQ,ZhaoZL.Insulin-likegrowthfactorbindingprotein-3(IGFBP-3)geneticvariantandtheriskofesophagealsquamouscellcarcinomainaChineseinsulation.GeneticsandMolecularResearch.2014;13(2):4146-53.
11.CaoL,LinJ,HeB,WangH,RaoJ,LiuY,ZhangX.AregulatoryvariantinCYP2E1affectstheriskoflungsquamouscellcarcinoma.TumorBiology.2014;35(1):455-462.
12.ZhangX,HuangM,WuX,KadlubarS,LinJ,YuX,FanC,NingB,KadlubarFF.GSTM1copynumberandpromoterhaplotypeaspredictorsforriskofrecurrenceand/orsecondprimarytumorinpatientswithheadandneckcancer.PharmgenomicsPersMed.2013;6:9-17.
13.LinZ,LinY,ZhangX,KadlubarS,TuoJ,GreenB,DengH,NingB.Differentialpromoteractivitiesoffunctionalhaplotypesinthe5’-flankingregionofhumansulfotransferase1A1.JBiochemMolToxicol.2012;26(10):422-428.
14.ZhangX,LinJ,WuX,LinZ,NingB,KadlubarS,KadlubarF.AssociationbetweenGSTM1copynumber,promotervariantsandsusceptibilitytourinarybladdercancer.IntJMolEpidemiolGenet.2012;3(3):228-236.
15.ZhangZ,YuX,GuoY,SongW,YuD,ZhangX.GeneticvariantinCASP3affectspromoteractivityandriskofesophagealsquamouscellcarcinoma.CancerScience.2012;103(3):555-60.
16.ZhangZ,YuD,YuanJ,GuoY,WangH,ZhangX.CigarettesmokingstronglymodifiestheassociationofCFHvariantandtheriskoflungcancer.CancerEpidemiology.2012;36(2):e111-5.
17.ZhangX,ZhongR,LiuL,WangY,YuanJ,WangP,SunC,ZhangZ,SongW,MiaoX.SmokingandCOX-2functionalpolymorphismsinteracttoincreasetheriskofgastriccardiaadenocarcinomainChinesepopulation.Plosone2011:6(7):e21894.
18.ZhangX,ZhongR,ZhangZ,YuanJ,LiuL,WangY,KadlubarS,FengF,MiaoX.InteractionofCyclooxygenase-2PromoterPolymorphismsWithHelicobacterpyloriInfectionandRiskofGastricCancer.MolecularCarcinogenesis.2011;50(11):876-883.
19.LiuL,WuC,WangY,ZhongR,WangF,ZhangX,DuanS,LouJ,YuD,TanW,YuanJ,WuT,NieS,MiaoX,LinD.AssociationofcandidategeneticvariationswithgastriccardiaadenocarcinomainChinesepopulation:amultiple-interactionanalysis.Carcinogenesis2011:32:336-342.
20.LiuL,YuanP,WuC,ZhangX,WangF,GuoH,ZhongR,XuY,WuJ,YuD,WuT,ZhangX,NieS,MiaoX,LinD.AssessmentofXPDLys751GlnandXRCC1T-77Cpolymorphismsinadvancednon-small-celllungcancerpatientstreatedwithplatinum-basedchemotherapy.LungCancer.2011;73:110-115.
21.KnappskogS,BjørnslettM,MyklebustLM,HuijtsPE,VreeswijkMP,EdvardsenH,GuoY,ZhangX,YangM,Ylisaukko-OjaSK,AlhopuroP,ArolaJ,TollenaarRA,vanAsperenCJ,SeynaeveC,StaalesenV,ChrisantharR,LøkkevikE,SalvesenHB,EvansDG,NewmanWG,LinD,AaltonenLA,Børresen-DaleAL,TellGS,StoltenbergC,RomundstadP,HveemK,LillehaugJR,VattenL,DevileeP,DørumA,LønningPE.TheMDM2PromoterSNP285C/309GHaplotypeDiminishesSp1TranscriptionFactorBindingandReducesRiskforBreastandOvarianCancerinCaucasians.CancerCell.2011;19(2):273-82.
22.YuX,DhakalI,BeggsM,EdavanaV,WilliamsS,ZhangX,MercerK,NingB,LangN,KadlubarF,KadlubarS.Functionalgeneticvariantsinthe3’-untranslatedregionofsulfotransferaseisoform1A1(SULT1A1)andtheireffectonenzymaticactivity.ToxicologicalSciences2010:118(2);391-403.
23.GuoY,ZhangX,YangM,MiaoX,ShiY,YaoJ,TanW,SunT,ZhaoD,YuD,LiuJ,LinD.FunctionalevaluationofmissensevariationsinthehumanMAD1L1andMAD2L1genesandtheirimpactonsusceptibilitytolungcancer.JournalofMedicalGenetics2010:47(9);616-622
24.ZhaoD,ZhangX,GuoY,TanW,LinD.Cyclooxygenase-2Gly587Argvariantisassociatedwithdifferentialenzymaticactivityandriskofesophagealsquamous-cellcarcinoma.MolecularCarcinogenesis2009;48(10):934-941
25.ZhaoD,XuD,ZhangX,WangL,TanW,GuoY,YuD,LiH,ZhaoP,LinD.InteractionofCyclooxygenase-2variantsandsmokinginpancreaticcancer:apossibleroleofnucleophosmin.Gastroenterology2009;136(5):1659-1668.PMID:19422084
26.YuD,ZhangX*,LiuJ,YuanP,TanW,GuoY,SunT,ZhaoD,MingY,LiuJ,XuB,LinD.CharacterizationofFunctionalExcisionRepairCross-ComplementationGroup1VariantsandTheirAssociationwithLungCancerRiskandPrognosis.ClinicalCancerResearch2008;14(9):2878–2886
27.LinZ,ZhangX*,TuJ,GuoY,GreenB,ChanC,TanW,HuangY,LingW,KadlubarFF,LinD,NingBT.AvariantofCokyneSyndromeBgeneERCC6confersriskoflungcancer.HumanMutation,2008;29(1):113–122
28.YangM,SunT,WangL,YuD,ZhangX,MiaoX,LiuJ,ZhaoD,LiH,TanW,LinD.Functionalvariantsincelldeathpathwaygenesandriskofpancreaticcancer.ClinicalCancerResearch2008;14(10):3230–3236.
29.ZhaoD,SunT,ZhangX,GuoY,YuD,YangM,TanW,WangG,LinD.RoleofCD14PromoterPolymorphismsinHelicobacterpyloriInfection-RelatedGastricCarcinoma.ClinicalCancerResearch2007;13(8):2362–2368.
30.GuoY,ZhangX,TanW,MiaoX,SunT,ZhaoD,LinD.Platelet12-lipoxygenaseArg261Glnpolymorphism:FunctionalcharacterizationandassociationwithriskofesophagealsquamouscellcarcinomaincombinationwithCOX-2polymorphisms.PharmacogeneticsandGenomics2007;17(3):197–205.
31.YangM,GuoY,ZhangX,MiaoX,TanW,SunT,ZhaoD,LiuJ,LinD.InteractionofP53Arg72ProandMDM2T309Gpolymorphismsandtheirassociationswithriskofgastriccardiacancer.Carcinogenesis2007;28(9):1996–2001.PMID:17638920
32.TanW,WuJ,ZhangX,GuoYL,LiuJ,SunT,ZhangB,ZhaoD,YangM,YuD,LinD.Associationsoffunctionalpolymorphismsincyclooxygenase-2andplatelet12-lipoxygenasewithriskofoccurrenceandadvanceddiseasestatusofcolorectalcancer.Carcinogenesis2007;28(6):1197–1201
33.ZhengL,DaiH,ZhouM,LiM,SinghP,QiuJ,TsarkW,HuangQ,KernstineK,ZhangX,LinD,ShenB.Fen1mutationsresultinautoimmunity,chronicinflammationandcancers.NatureMedicine2007;13(7):812–819.PMID:17589521
34.SunT,GaoY,TanW,MaS,ShiY,YaoJ,GuoY,YangM,ZhangX,ZhangQ,ZengC,LinDX.Asix-nucleotideinsertion-deletionpolymorphismintheCASP8promoterisassociatedwithsusceptibilitytomultiplecancers.NatureGenetic2007;39(5):605–613.PMID:17450141
35.ZhangB,SunT,XueL,HanX,ZhangB,LuN,ShiYK,TanW,ZhouYF,ZhaoD,ZhangX,GuoY,LinD.FunctionalpolymorphismsinFASandFASLcontributetoincreasedapoptosisoftumorinfiltrationlymphocytesandriskofbreastcancer.Carcinogenesis2007;28(5):1067–1073.
36.MiaoX,ZhangX,ZhangL,GuoY,HaoB,TanW,HeF,LinD.AdenosineDiphosphateRibosylTransferaseandX-RayRepairCross-Complementing1polymorphismsinGastricCardiaCancer.Gastroenterology2006;131(2):420–427.
37.ZhangX,MiaoX,GuoY,TanT,ZhouY,SunT,WangY,LinD.GeneticpolymorphismsincellcycleregulatorygenesMDM2andTP53areassociatedwithsusceptibilitytolungcancer.HumanMutation2006;27(1):110–117.
38.SunT,GaoY,TanW,MaS,ZhangX,WangY,ZhangQ,GuoY,ZhaoD,ZengC,LinD.HaplotypesinMatrixMetalloproteinaseGeneClusteronChromosome11q22ContributetotheRiskofLungCancerDevelopmentandProgression.ClinicalCancerResearch2006;12(23):7009–7017.
39.LiY,ZhangX,HuangG,MiaoX,GuoL,LinD,LuS.IdentificationofanovelpolymorphismArg290Glnofesophagealcancerrelatedgene1(ECRG1)anditrelatedrisktoesophagealsquamouscellcarcinoma.Carcinogenesis2006;27(4):798–802.
40.LiuF,PanK,ZhangX,ZhangY,ZhangL,MaJ,LinD,YouW.Geneticpolymorphismsofcyclooxygenase-2,expressionandriskofgastriccanceranditsprecursorsinaChinesepopulation.Gastroenterology,2006;130(7):1975–1984.
41.HaoB,MiaoX,LiY,ZhangX,SunT,LiangG,ZhaoY,ZhouY,WangH,ChenX,ZhangL,TanW,WeiQ,LinD,HeF.AnovelT-77CpolymorphisminDNArepairgeneXRCC1contributestodiminishedpromoteractivityandincreasedriskofnon-smallcelllungcancer.Oncogene2006;25(25):3613–3620.
42.ZhangX,MiaoX,TanW,NingB,LiuZ,HongY,SongW,GuoY,ZhangX,ShenY,QiangB,KadlubarFF,LinD.Identificationoffunctionalgeneticvariantsincyclooxygenase-2andtheirassociationwithriskofesophagealcancer.Gastroenterology2005;129(2):565–576.
43.ZhangX,MiaoX,SunT,TanW,QuS,XiongP,ZhouY,LinD.FunctionalpolymorphismsincelldeathpathwaygenesFASandFASLcontributetoriskoflungcancer.JournalofMedicalGenetics2005;42(6):479–484.
44.ZhangX,MiaoX,LiangG,HaoB,WangY,TanW,LiY,GuoY,HeF,WeiG,LinD.PolymorphismsinDNAbaseexcisionrepairgenesADPRTandXRCC1andriskoflungcancer.CancerResearch2005;65(3):722–726.
45.SunT,ZhouY,LiH,HanX,ShiY,WangL,MiaoX,TanW,ZhaoD,ZhangX,GuoY,LinDX.FASL-844Cpolymorphismisassociatedwithincreasedactivation-inducedTcelldeathandriskofcervicalcancer.JournalofExperimentalMedicine2005;202(7):967–974.
46.TanW,MiaoX,WangL,YuC,XiongP,LiangG,SunT,ZhouY,ZhangX,LiH,LinDX.Significantincreaseinriskofgastroesophagealcancerisassociatedwithinteractionbetweenpromoterpolymorphismsinthymidylatesynthaseandserumfolatestatus.Carcinogenesis2005;26(8):1430–1435.
47.ZhouY,YuC,MiaoX,WangY,TanW,SunT,ZhangX,XiongP,LinD.Functionalhaplotypesinthepromoterofmatrixmetalloproteinase-2andlungcancersusceptibility.Carcinogenesis2005;26(6):1117–1121.
48.HongY,MiaoX,ZhangX,GuoY,TanW,LiuZ,LinD.TheroleofP53andMDM2polymorphismsinriskofesophagealsquamouscellcarcinoma.CancerResearch2005;65(20):9582–9587.
49.SunT,MiaoX,ZhangX,TanW,XiongP,LinD.PolymorphismsofdeathpathwaygenesFASandFASLinesophagealsquamous-cellcarcinoma.JournalofNationalCancerInstitute2004;96(13):1030–1036.
50.MiaoX,SunT,WangY,ZhangX,TanW,LinD.FunctionalSTK15Phe31Ilepolymorphismisassociatedwiththeoccurrenceandadvanceddiseasestatusofesophagealsquamouscellcarcinoma.CancerResearch2004;64(8):2680–2683.
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