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个人简介

江苏大学副教授,2014年获得浙江大学药学院博士学位,于2016年—2018年在美国佐治亚理工学院(GeorgiaInstituteofTechnology)进行为期2年的访学研究,先后承担国家自然科学基金、江苏省自然科学基金、中国博士生后基金特别资助和一等资助、江苏省博士后基金、江苏省高校自然科学基金等多个项目。在Angew.Chem.Int.Ed(IF:12.3).,Nanolett.(IF:12.3),Small(IF:10.8),Biomaterials(IF:10.8),Nanoscale(IF:7.2)等期刊发表SCI论文30余篇。 研究项目: [1]主持国家自然科学基金:pH/NIR双重智能响应系统靶向联合治疗类风湿关节炎的研究,项目号:81503017,起止时间:2016.1-2018.12。 [2]主持江苏省自然科学基金:pH/NIR智能响应系统治疗类风湿关节炎的作用机制研究,项目号:BK20150534,起止时间:2016.1-2018.12。 [3]主持中国博士后基金项目(特别资助):磁性分子印迹聚合物用于肠道内毒素特异识别及清除研究,项目号:2016T90433,起止时间:2016.3-2018.3 [4]主持中国博士后基金项目(一等资助):基于氧化铁的诊断治疗系统在类风湿关节炎中的应用,项目号:2015M580404,起止时间:2014.7-2016.6 [5]主持江苏省博士后基金项目:线粒体靶向给药系统的构建及其在肿瘤声动力治疗中的应用,项目号:1402075B,起止时间:2014.12-2016.11。 [6]主持江苏大学高级人才科研启动基金:Yolk-Shell结构的光触发释药系统的构建及其光热-化疗联合抗肿瘤应用研究,项目号:14JDG181,起止时间:2014.7-2016.6。 [7]主持江苏省教育厅高校自然科学基金:基于Fe3O4的智能光控给药系统的构建及应用研究,项目号:15KJB350001,起止时间:2015.7-2017.6. [8]参与国家自然科学基金:新型多功能碳纳米管基因传递系统的构建及性能研究,项目号:81172999,起止时间:2012.1~2015.12。 [9]参与国家自然科学基金:TRAIL介导基于无机材料的层次化双重靶向肿瘤联合治疗给药系统构建及机制研究,项目号:81373347,起止时间:2014.1~2017.12。

研究领域

主要从事智能靶向载体的构建及评价、新型肿瘤治疗技术、肿瘤成像及诊断技术等方向的研究工作,

近期论文

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[19]SongShen*,LeiFeng,ShunyaoQi,JinCao,YanruGe,LinWu*,ShuWang*.ReversibleThermochromicNanoparticlesComposedofaEutecticMixtureforTemperature-ControlledPhotothermalTherapy.NanoLett.2020,DOI:10.1021/acs.nanolett.0c00147. [18]SongShen,ChunleiZhu,DaHuo,MiaoxinYang,JiajiaXue,YounanXia*.AHybridNanomaterialfortheControlledGenerationofFreeRadicalsandOxidativeDestructionofHypoxicCancerCells.Angew.Chem.Int.Ed.2017,56,8801–8804. [17]SongShen*,FeiHan,AnranYuan,LinWu*,JinCao,JingQian,XueyongQi,YongshengYan,YanruGe*.Engineerednanoparticlesdisguisedasmacrophagesfortrappinglipopolysaccharideandpreventingendotoxemia Biomaterials,2019,189,60-68. [16]SongShen,MarhabaMamat,ShengchangZhang,JinCao,ZacharyD.Hood,LegnaFigueroa-Cosme,andYounanXia*.SynthesisofCaO2NanocrystalsandTheirSphericalAggregateswithUniformSizesforUseasaBiodegradableBacteriostaticAgent.Small2019,1902118. [15]SongShen*,D.Huang,J.Cao,Y.Chen,X.Zhang,S.Guo,W.Ma,X.Qi,Y.Ge*andL.Wu*.Magneticliposomesforlight-sensitivedrugdeliveryandcombinedphotothermal–chemotherapyoftumors.J.Mater.Chem.B,2019,7,1096 [14]LinWu,SongShen*.Whatpotentialdomagneticironoxidenanoparticleshaveforthetreatmentofrheumatoidarthritis?Nanomedicine,2019,14(8),927–930. [13]LinWu,LingZong,HaihuaNi,XuexueLiu,WenWen,LeiFeng,JinCao*,XueyongQi,YanruGe*,andSongShen*.MagneticThermosensitiveMicelleswithUpperCriticalSolutionTemperatureforNIRTriggeredDrugRelease.Biomater.Sci.2019,7,2134 [12]SongShen,BeiDing,ShengchangZhang,XueyongQi*,KunWang,JieTian,YongshengYan,YanruGe*andLinWu*.Near-InfraredLight-ResponsiveNanoparticleswithThermosensitiveYolk-ShellStructureforMultimodalImagingandChemo-PhotothermalTherapyofTumor.Nanomed:Nanotech.Biol.Med.,2017,13(5):1607-1616. [11]ShenS,KongFF,GuoXM,WuL,ShenHJ,XieM,WangXS,JinYi*,GeYR*.CMCTSstabilizedFe3O4nanoparticleswithextremelylowtoxicityashighlyefficientnear-infraredphotothermalagentsforinvivotumorablation.Nanoscale,2013,5,8056–8066. [10]LingChen,LinWu,FeiLiu,XueyongQi,YanruGe*andSongShen*.Azo-functionalizedFe3O4nanoparticles:anear-infraredlighttriggereddrugdeliverysystemforcombinedtherapyofcancerwithlowtoxicity.J.Mater.Chem.B,2016,4,3660-3669. [9]LinWu,LingChen,FeiLiu,XueyongQi,YanruGe,SongShen*.Remotelycontrolleddrugreleasebasedonironoxidenanoparticlesforspecifictherapyofcancer.ColloidsSurfBBiointerfaces,2017,152:440–448. [8]ShengchangZhang,LinWu,JinCao,KailiWang,YanruGe,WanjunMa,XueyongQi,SongShen*.Effectofmagneticnanoparticlessizeonrheumatoidarthritistargetingandphotothermaltherapy.ColloidsandSurfacesB:Biointerfaces,170(2018)224–232. [7]SongShen,LinWu,MengXie,HaijunShen,XueyongQi,YongminYan,YanruGeandYiJin.Core-shellstructuredFe3O4@TiO2nanoparticlesfortargetedchemo-sonodynamictherapyofcancer.Int.J.Pharm.,2015,486,380–388(IF:3.785). [6]SongShen,XiaomengGuo,LinWu,MengWang,XinshiWang,FenfenKong,HaijunShen,MengXie,YanruGe,YiJin.Dual-core@shell-structuredFe3O4-NaYF4@TiO2NanocompositesasMagneticTargetingDrugCarrierforBioimagingandCombinedChemo-sonodynamicTherapy.J.Mater.Chem.B,2014,2,5775.(IF:4.8) [5]MengJiaChen,AirenXu,WenyueHe,WeichengMa*,SongShen*.Ultrasoundtriggereddrugdeliveryformitochondriatargetedsonodynamictherapy.JDrugDelivSciTec,2017,39,501–507. [4]BeiDing,SongShen*,LinWu,XueyongQi,HaihuaNi,YanruGe.DoxorubicinloadedFe3O4@SiO2nanoparticlesasmagnetictargetingagentsforcombinedphotothermal-chemotherapyofcancer.Chemistryletters,2015,6,858-860(IF:1.4). [3]FeiLiu,LinWu,LingChen,XueyongQi,YanruGe,andSongShen.Ultrasound-guidedTumorSonodynamicTherapyBasedonSonosensitizerLiposome.Chem.Lett.2016,45,1304–1306. [2]SongShen,BeiDing,LinWu,XueyongQi,Yanru,Ge.Fe3O4@TiO2nanocompositesformagnetictargetingsonodynamictherapyofcancer.KeyEngineeringMaterials,2015,636:129-132.(EI) [1]SongShen,BeiDing,QingLi,XuweiYu,XueyongQi,YanruGe.Anovelchitosanmicrobubbleasultrasound-triggereddrugcarrierforantitumorinvitro.KeyEngineeringMaterials,2015,636:139-143.(EI)

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