个人简介
学习经历:
2003.09-2007.06南京理工大学生物工程专业,获学士学位;
2007.09-2012.06南京理工大学分子代谢中心,获博士学位;
工作经历:
2012.06-至今江苏大学医学院,讲师。
【主讲课程】
医学生物化学,MBBS国际班生物化学与分子生物学。
【主持科研项目】
江苏大学高级专业人才科研启动基金,伤寒沙门菌sRNA1068的功能及分子机制研究(13JDG026),2013.06-2016.06,主持。
江苏省自然科学基金青年基金,伤寒沙门菌sRNA1068的作用及分子机制研究(BK20130504),2013.07-2016.06,结题。
国家自然科学基金青年基金,malS-5'UTR调节伤寒沙门菌耐酸力和侵袭力的作用机制研究(31400125),2015.01-2017.12,主持。
近期论文
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1.ZhangY,WangZ,ZhaoY,ZhaoM,WangS,HuaZ,ZhangJ.Theplasma5'-AMPactsasapotentialupstreamregulatorofhyperglycemiaintype2diabeticmice.AmJPhysiolEndocrinolMetab,2012,302(3):E325-333.
2.ZhangY,XiaL,PangW,WangT,ChenP,ZhuB,ZhangJ.Anovelsolubleβ-1,3-D-glucanSalecanreducesadiposityandimprovesglucosetoleranceinhigh-fatdiet-fedmice.BrJNutr,2013,109(2):254-262.
3.ZhangY,YanD,XiaL,ZhaoX,Osei-AdjeiG,XuS,ShengX,HuangX.ThemalS-5'UTRregulateshisG,akeygeneinthehistidinebiosyntheticpathwayinSalmonellaentericaserovarTyphi.CanJMicrobiol.2017,63(4):287-295.
4.PangW#,ZhangY#,WangS,JiaA,DongW,CaiC,HuaZ,ZhangJ.ThemPlrp2andmClpsgenesareinvolvedinthehydrolysisofretinylestersinthemouseliver.JLipidRes,2011,52(5):934-941.(共同第一作者)
5.ZhangQ#,ZhangY#,ZhangX#,ZhanL,ZhaoX,XuS,ShengX,HuangX.Thenovelcis-encodedantisenseRNAAsrCpositivelyregulatestheexpressionofrpoE-rseABCoperonandthusenhancesthemotilityofSalmonellaentericaserovartyphi.FrontMicrobiol.2015,6:990.(共同第一作者)
6.张盈,夏琳,逄文强,王涛,张建法.腺苷酸激酶与AMP信号在感知及维持机体能量中的作用.生命科学,2011,23(5):434-439.
7.ZhangY,ZhangY,GaoH,ZhangL,YinZ,HuangX,ZhouD,YangH,YangW,WangL.VibrioparahaemolyticusCalRdownregulatesthethermostabledirecthemolysin(TDH)genetranscriptionandtherebyinhibitshemolyticactivity.Gene.2017,613:39-44.
8.XiaL,WangZ,ZhangY,YangX,ZhanY,ChengR,WangS,ZhangJ.Reciprocalregulationofinsulinandplasma5’-AMPinglucosehomeostasisinmice.JournalofEndocrinology,2015,224:225-234.
9.XiaL,MaS,ZhangY,WangT,ZhouM,WangZ,ZhangJ.DailyvariationinglobalandlocalDNAmethylationinmouselivers.PLoSOne,2015,10:e0118101.
10.JiY,LiW,ZhangY,ChenL,ZhangY,ZhengX,HuangX,NiB.QseBmediatesbiofilmformationandinvasioninSalmonellaentericaserovarTyphi.MicrobPathog.2017,104:6-11.
11.ZhangL,Osei-AdjeiG,ZhangY,GaoH,YangW,ZhouD,HuangX,YangH,ZhangY.CalRisrequiredfortheexpressionofT6SS2andtheadhesionofVibrioparahaemolyticustoHeLacells.ArchMicrobiol.2017,199(6):931-938.
12.GongM,XuS,JinY,ZhangY,DadzieI,ZhangX,WangZ,ZhuY,NiB,ShengX,HuangX.5'-UTRofmalSincreasestheinvasivecapacityofSalmonellaentericaserovarTyphibyinfluencingtheexpressionofbax.FutureMicrobiol.2015,10:941-954.
13.Osei-AdjeiG,GaoH,ZhangY,ZhangL,YangW,YangH,YinZ,HuangX,ZhangY,ZhouD.RegulatoryactionsofToxRandCalRontheirowngenesandtypeIIIsecretionsystem1inVibrioparahaemolyticus.Oncotarget.2017,8:65809-65822.
14.DadzieI,NiB,GongM,ZhangY,ZhangH,ShengX,XuS,HuangX.IdentificationandcharacterizationofacisantisenseRNAoftheparCgeneencodingDNAtopoisomeraseIVofSalmonellaentericaserovarTyphi.ResMicrobiol,2014,165(6):439-446.