张义全 - 江苏大学

个人简介

张义全,男，1985年生，副教授，硕士生导师，江苏大学优秀青年骨干教师。主要从事病原菌致病机制研究。作为负责人，承担国家自然科学基金青年科学基金和江苏省自然科学基金青年科学基金，各1项。公开发表学术论文60余篇，其中第一作者或通讯作者SCI论文30余篇，代表性杂志包括JournalofBacteriology、EnvironmentalMicrobiology,BMCMicrobiology、FutureMicrobiology、FrontiersinMicrobiology、FrontiersinCellularandInfectionMicrobiology等。参编中文专著3部，英文专著1部。主持的科研项目： 1.江苏省自然科学基金青年基金，BK20160505，CalR调控副溶血弧菌VI型分泌系统的分子机制研究，2016/07-2019/06，19万元，在研，主持； 2.国家自然科学基金青年基金，81601809，副溶血弧菌ToxR对III分泌系统和耐热性直接溶血素的表达调控研究，2017/01-2019/12，18万元，在研，主持； 3.国家自然科学基金面上项目（合作申报），31671290，副溶血弧菌毒力基因表达的密度感应调控机制，2017/01-2020/12，21万元，在研，共同主持； 4.病原微生物生物安全国家重点实验室开放课题，SKLPBS1438，密度感应系统调控副溶血弧菌III型分泌系统的分子机制研究，2015/01-2016/12，20万元，已结题，主持； 5.江苏大学科研启动基金资助项目，1291280020，H-NS调控副溶血弧菌生物膜形成的分子机制研究，2015/01-2016/12，5万元，已结题，主持。

近期论文

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1.RenfeiLu*,HaoTang*,YueQiu,WenhuiYang,HuiyingYang,DongshengZhou,XinxiangHuang,LingfeiHu#,YiquanZhang#.QuorumsensingregulatesthetranscriptionoflateralflagellargenesinVibrioparahaemolyticus.FutureMicrobiology,2019,accepted. 2.YiquanZhang,LingfeiHu,YueQiu,GeorgeOsei-Adjei,HaoTang,YingZhang,RuiZhang,XiumeiSheng,ShungaoSheng,WenhuiYang,HuiyingYang,ZheYin,RuifuYang,XinxiangHuang,DongshengZhou#.QsvRintegratesintoquorumsensingcircuittocontrolVibrioparahaemolyticusvirulence.EnvironmentalMicrobiology,2019,21(3):1054-1067.(doi:10.1111/1462-2920.14524) 3.YiquanZhang,LingfeiHu,GeorgeOsei-Adjei,YingZhang,WenhuiYang,ZheYin,RenyunLu,XiumeiSheng,RuifuYang,XinxiangHuang#,DongshengZhou#.AutoregulationofToxRanditsregulatoryactionsonmajorvirulencegenelociinVibrioparahaemolyticus.FrontiersinCellularandInfectionMicrobiology,2018,8:291.(doi:10.3389/fcimb.2018.00291) 4.YiquanZhang.2018.GeneticRegulationAnalysisofYersiniapestis.Springerbook:YersiniapestisProtocols,Chapter22,pages183-202. 5.HeGao*,JialiangXu*,XinLu,JieLi,JingLou,HongqunZhao,BaoweiDiao,QiannanShi,YiquanZhang#,BiaoKan#.ExpressionofhemolysinisregulatedunderthecollectiveactionsofHapR,Fur,andHlyUinVibriocholeraeElTorserogroupO1.FrontiersinMicrobiology,2018,9:1310.(doi:10.3389/fmicb.2018.01310) 6.LeiLiu,HaihongFang,YinjuanDing,YaqiongZheng,LipingCai,ShangenZheng#,YiquanZhang#.TranscriptionalregulationbetweenthetwoglobalregulatorsRovAandCRPinYersiniapestisbiovarMicrotus.CurrentMicrobiology,2018,8:374.(doi:10.3389/fcimb.2018.00347) 7.LongChen,YueQiu,HaoTang,LingfeiHu,WenhuiYang,XiaojueZhu,XinxiangHuang,TangWang#,YiquanZhang#.ToxRisrequiredforbiofilmformationandmotilityofVibrioparahaemolyticus.BiomedicalandEnvironmentalSciences,2018,31(11):848-850.(doi:10.3967/bes2018.112) 8.RenfeiLu,GeorgeOsei-Adjei,XinxiangHuang,YiquanZhang#.RoleandregulationoftheorphanAphAproteinofquorumsensinginpathogenicVibrios.FutureMicrobiology,2018,13:383-391.(doi:10.2217/fmb-2017-0165) 9.LinlinZhang,YiweiWeng,YuWu,XueyingWang,ZheYin,HuiyingYang,WenhuiYang#,YiquanZhang#.H-NSisanactivatorofexopolysaccharidebiosynthesisgenestranscriptioninVibrioparahaemolyticus.MicrobialPathogenesis,2018,116:164-167.(doi:10.1016/j.micpath.2018.01.025) 10.YingZhang,LinXia,LipingLin,HaoTang,GeorgeOsei-Adjei,ShungaoXu,YiquanZhang#,XinxiangHuang#.ReciprocalregulationofOmpRandHfqandtheirregulatoryactionsontheVipolysaccharidecapsularantigeninSalmonellaentericaSerovarTyphi.CurrentMicrobiology,2018,75(6):773-778.(doi:10.1007/s00284-018-1447-7) 11.GeorgeOsei-Adjei,XinxiangHuang,YiquanZhang#.TheextracellularproteasesproducedbyVibrioparahaemolyticus.WorldJournalofMicrobiology&Biotechnology,2018,24(5):68.(doi:10.1007/s11274-018-2453-4) 12.QinCai,YiquanZhang#.Structure,functionandregulationofthethermostabledirecthemolysin(TDH)inpandemicVibrioparahaemolyticus.MicrobialPathogenesis,2018,123:242-245.(doi:10.1016/j.micpath.2018.07.021) 13.YiquanZhang,HeGao,GeorgeOsei-Adjei,YingZhang,WenhuiYang,HuiyingYang,ZheYin,XinxiangHuang#,DongshengZhou#.TranscriptionalRegulationoftheTypeVISecretionSystem1GenesbyQuorumSensingandToxRinVibrioparahaemolyticus.FrontiersinMicrobiology,2017,8.(doi:10.3389/fmicb.2017.02005) 14.GeorgeOsei-Adjei*,HeGao*,YingZhang,LingyuZhang,WenhuiYang,HuiyingYang,ZheYin,XinxiangHuang#,YiquanZhang#,DongshengZhou#.RegulatoryactionsofToxRandCalRontheirowngenesandtypeIIIsecretionsystem1inVibrioparahaemolyticus.Oncotarget,2017,8(39):65809-65822.(doi:10.18632/oncotarget.19498) 15.HeGao,LingyuZhang,GeorgeOsei-Adjei,WenhuiYang,DongshengZhou,XinxiangHuang,HuiyingYang,ZheYin#,YiquanZhang#.TranscriptionalregulationofcpsQ-mfpABCandmfpABCbyCalRinVibrioparahaemolyticus.MicrobiologyOpen,2017,6(4):e470.(doi:10.1002/mbo3.470) 16.LingyuZhang,GeorgeOsei-Adjei,YingZhang,HeGao,WenhuiYang,DongshengZhou,XinxiangHuang#,HuiyingYang#,YiquanZhang#.CalRisrequiredfortheexpressionofT6SS2andtheadhesionofVibrioparahaemolyticustoHeLacells.ArchivesofMicrobiology,2017,199(6):931-938.(doi:10.1007/s00203-017-1361-6) 17.YiquanZhang,YingZhang,HeGao,LingyuZhang,ZheYin,XinxiangHuang,DongshengZhou,HuiyingYang,WenhuiYang#,LiWang#.VibrioparahaemolyticusCalRdownregulatesthethermostabledirecthemolysin(TDH)genetranscriptionandtherebyinhibitshemolyticactivity.Gene,2017,613:39-44.(doi:10.1016/j.gene.2017.03.001) 18.YiquanZhang,GeorgeOsei-Adjei,BinNi,HaihongFang,LingyuZhang,XinZhao,XinxiangHuang,HuiyingYang,WenhuiYang#,FengjunSun#.TranscriptionofexsDisrepresseddirectlybyH-NSinVibrioparahaemolyticus.MicrobialPathogenesis,2016,97:221-5.(doi:10.1016/j.micpath) 19.YiquanZhang,LingyuZhang,ShuningHou,XinxiangHuang,FengjunSun,HeGao#.Themasterquorum-sensingregulatorOpaRisactivatedindirectlybyH-NSinVibrioparahaemolyticus.CurrentMicrobiology,2016,73(1):71-6.(doi:10.1007/s00284-016-1018-8) 20.YiquanZhang,FengjunSun,HuiyingYang,LeiLiu,BinNi,XinxiangHuang,RuifuYang,DongshengZhou#.CurrentMicrobiology,2015,70(3):398-403.(doi:10.1007/s00284-014-0736-z)