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个人简介

教育经历: 2007/9-2012/6,江苏大学,临床检验诊断学专业,研究生,医学博士 2002/9-2007/7,江苏大学,医学检验专业,本科,医学学士 工作经历: 2015/7-至今,江苏大学,临床检验与输血学教研室,副教授,硕士生导师 2014/1-2015/6,江苏大学,临床检验与输血学教研室,讲师,硕士生导师 2012/6-2013/12,江苏大学,临床检验与输血学教研室,讲师 主持或参加科研项目及人才计划项目情况: 主持科研项目 1.国家自然基金面上项目,81772641,区域淋巴结转移胃癌exosome重塑骨髓MSC作用及其分子机制,2018/01-2021/12,58万 2.中国博士后科学基金面上项目,2017M611740,骨髓MSC促淋巴结转移胃癌恶化作用及其分子机制,2017/05-2018/11,5万 3.江苏省博士后基金,1701027A,淋巴结转移胃癌exosome重塑骨髓MSC促胃癌作用及机制,2017/10-2019/05,6万 4.国家自然基金青年基金,81302119,胃癌MSC源性miRNAs再编程骨髓MSC作用及机制研究,2014/01-2016/12,23万 5.江苏省自然科学基金,BK20130540,microRNA再编程骨髓间质干细胞转分化及机制研究,2013/06-2016/07,20万 6.江苏省普通高校自然科学研究项目,13KJB320001,microRNA调控骨髓MSC向胃癌MSC转分化及机制研究,2013/08-2015/12,3.2万 7.江苏大学“青年骨干教师培养工程”青年学术带头人2014/01-2017/126万 参与科研项目 1.国家自然基金面上项目,81472334,胃癌MSC源性细胞因子调节Th17/Treg细胞分化作用机制及其临床应用,2015/01-2018/12,70万排名3 2.国家自然基金面上项目,81071421,GC-MSC和癌组织来源的MicroRNAs 在胃癌诊治中的作用,2011/01-2013/12,36万排名2 3.江苏省科技厅临床医学科技专项,BL2012055,癌相关间质干细胞源性miRNA分析技术在胃癌分子诊断中的应用,2012/01-2015/12,100万排名2 获奖情况: 1.2016年获镇江市优秀科技论文一等奖 2.2016年获镇江市优秀科技论文三等奖 3.2015年获临床应用生物化学与分子生物学分会2015年学术年会青年学者学术论文二等奖 4.2014年获江苏大学第七届教师教学竞赛新教师组三等奖 5.2014年获江苏大学“青年骨干教师培养工程”青年学术带头人培育人选称号 6.2013年获镇江市优秀科技论文一等奖

近期论文

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1.WangM,YangF,QiuR,ZhuM,ZhangH,XuW,ShenB,ZhuW.Theroleofmmu-miR-155-5p-NF-κBsignalingintheeducationofbonemarrow-derivedmesenchymalstemcellsbygastriccancercells,CancerMed,2018Feb14.doi:10.1002/cam4.1355第一作者/通讯作者(SCIIF:3.362) 2.WangM,ChenB,SunXX,ZhaoXD,ZhaoYY,SunL,XuCG,ShenB,SuZL,XuWR,ZhuW.Gastriccancertissue-derivedmesenchymalstemcellsimpactperipheralbloodmononuclearcellsviadisruptionofTreg/Th17balancetopromotegastriccancerprogression,ExpCellRes,2017,361(1):19-29第一作者(SCIIF:3.546) 3.HuangF,WangD,YaoY,WangM.PDGFsignalingincancerprogression,IntJClinExpMed,2017,10(7):9918-9929通讯作者(SCIIF:1.069) 4.ZhuM,WangM,YangF,TianY,CaiJ,YangH,FuH,MaoF,ZhuW,QianH,XuW.miR-155-5pinhibitionpromotesthetransitionofbonemarrowmesenchymalstemcellstogastriccancertissuederivedMSC-likecellsviaNF-κBp65activation,Oncotarget,2016,7(13):16567-16580共同第一作者/通讯作者(SCIIF:5.165) 5.CaiJ,WangM,ZhuM,ZhangQ,ZhangX,YanY,QianH,XuW.N-methyl-N-nitro-N'-nitrosoguanidineinducestheexpressionofCCR2inhumangastricepithelialcellspromotingCCL2-mediatedmigration,MolMedRep,2016,13(2):1083-1090共同第一作者(SCIIF:1.692) 6.WangM,CaiJ,HuangF,ZhuM,ZhangQ,YangT,ZhangX,QianH1,XuW.Pre-treatmentofhumanumbilicalcord-derivedmesenchymalstemcellswithinterleukin-6abolishestheirgrowth-promotingeffectongastriccancercells,IntJMolMed,2015,35(2):367-375第一作者(SCIIF:2.341) 7.ZhangB,WangM,GongA,ZhangX,WuX,ZhuY,ShiH,WuL,ZhuW,QianH,XuW.HucMSC-exosomemediated-Wnt4signalingisrequiredforcutaneouswoundhealing,StemCells,2015,33(7):2158-2168共同第一作者(SCIIF:5.599) 8.WangM,ZhaoC,ShiH,ZhangB,ZhangL,ZhangX,WangS,WuX,YangT,HuangF,CaiJ,ZhuQ,ZhuW,QianH,XuW.DeregulatedmicroRNAsingastriccancertissue-derivedmesenchymalstemcells:novelbiomarkersandamechanismforgastriccancer,BrJCancer,2014,110(5):1199-1210第一作者(SCI检索IF:6.176)高被引用论文 9.HuangF,WangM,YangT,CaiJ,ZhangQ,SunZ,WuX,ZhangX,ZhuW,QianH,XuW.Gastriccancer-derivedMSC-secretedPDGF-DDpromotesgastriccancerprogression,JCancerResClinOncol,2014,140(11):1835-1848共同第一作者(SCIIF:3.503) 10.ZhangQ,WangM,HuangF,YangT,CaiJ,ZhangX,ZhuW,QianH,XuW.H.pyloriinfection-inducedMSCdifferentiationintoCAFspromotesepithelial-mesenchymaltransitioningastricepithelialcells,IntJMolMed,2013,32(6):1465-1473共同第一作者(SCIIF:2.341) 11.WangM,GuH,QianH,ZhuW,ZhaoC,ZhangX,TaoY,ZhangL,XuW.miR-17-5p/20aareimportantmarkersforgastriccancerandmurinedoubleminute2participatesintheirfunctionalregulation,EurJCancer,2013,49(8):2010-2021第一作者(SCIIF:6.029) 12.WangM,GuH,WangS,QianH,ZhuW,ZhangL,ZhaoC,TaoY,XuW.CirculatingmiR-17-5pandmiR-20a:molecularmarkersforgastriccancer,MolMedRep,2012,5(6):1514-1520第一作者(SCIIF:1.692) 13.XuR,ZhaoX,ZhaoY,ChenB,SunL,XuC,ShenB,WangM,XuW,ZhuW.EnhancedgastriccancergrowthpotentialofmesenchymalstemcellsderivedfromgastriccancertissueseducatedbyCD4+Tcells,CellProlif,2017Oct22.doi:10.1111/cpr.12399.(SCIIF:4.111) 14.QianH,DingX,ZhangJ,MaoF,SunZ,JiaH,YinL,WangM,ZhangX,ZhangB,YanY,ZhuW,XuW.CancerstemnessandmetastaticpotentialofthenoveltumorcelllineK3:aninnermutatedcellofbonemarrow-derivedmesenchymalstemcells.Oncotarget,2017,8(24):39522-39533(SCIIF:5.165) 15.ZhuY,YuJ,YinL,ZhouY,SunZ,JiaH,TaoY,LiuW,ZhangB,ZhangJ,WangM,ZhangX,YanY,XueJ,GuH,MaoF,XuW,QianH.MicroRNA-146b,aSensitiveIndicatorofMesenchymalStemCellRepairofAcuteRenalInjury,StemCellsTranslMed,2016,5(10):1406-1415(SCIIF:4.247) 16.ZhangB,ShiY,GongA,PanZ,ShiH,YangH,FuH,YanY,ZhangX,WangM,ZhuW,QianH,XuW.HucMSCExosome-Delivered14-3-3ζOrchestratesSelf-ControloftheWntResponseviaModulationofYAPDuringCutaneousRegeneration,StemCells,2016,34(10):2485-2500(SCIIF:5.599) 17.MaoF,WangM,WangJ,XuWR.Theroleof15-LOX-1incolitisandcolitis-associatedcolorectalcancer,InflammRes,2015,64(9):661-669(SCIIF:2.659) 18.XuXJ,GaoS,WangM,QianH,GuGY,ZhangK,XuWR.MethylationstatusoftheFHITgeneinthetransformedhumanmesenchymalF6stemcellline,OncolLett,2015,9(6):2661-2666(SCIIF:1.39) 19.JiR,ZhangB,ZhangX,XueJ,YuanX,YanY,WangM,ZhuW,QianH,XuW.Exosomesderivedfromhumanmesenchymalstemcellsconferdrugresistanceingastriccancer,CellCycle,2015,14(15):2473-2483(SCIIF:3.53) 20.ZhuQ,ZhangX,ZhangL,LiW,WuH,YuanX,MaoF,WangM,ZhuW,QianH,XuW.TheIL-6-STAT3axismediatesareciprocalcrosstalkbetweencancer-derivedmesenchymalstemcellsandneutrophilstosynergisticallypromptgastriccancerprogression,CellDeathDis,2014,5:e1295(SCIIF:5.965) 21.YangT,ZhangX,WangM,ZhangJ,HuangF,CaiJ,ZhangQ,MaoF,ZhuW,QianH,XuW.ActivationofmesenchymalstemcellsbymacrophagespromptshumangastriccancergrowththroughNF-κBpathway,PLoSOne,2014,9(5):e97569(SCIIF:2.806) 22.ZhangL,XuZ,XuX,ZhangB,WuH,WangM,ZhangX,YangT,CaiJ,YanY,MaoF,ZhuW,ShaoQ,QianH,XuW.SALL4,anovelmarkerforhumangastriccarcinogenesisandmetastasis,Oncogene,2014,33(48):5491-5500(SCIIF:7.519) 23.LiW,ZhangQ,WangM,WuH,MaoF,ZhangB,JiR,GaoS,SunZ,ZhuW,QianH,ChenY,XuW.Macrophagesareinvolvedintheprotectiveroleofhumanumbilicalcord-derivedstromalcellsinrenalischemia-reperfusioninjury,StemCellRes,2013,10(3):405-416(SCIIF:3.892) 24.LiT,YanY,WangB,QianH,ZhangX,ShenL,WangM,ZhouY,ZhuW,LiW,XuW.Exosomesderivedfromhumanumbilicalcordmesenchymalstemcellsalleviateliverfibrosis,StemCellsDev,2013,22(6):845-854(SCIIF:3.562) 25.ZhuW,HuangL,LiY,ZhangX,GuJ,YanY,XuX,WangM,QianH,XuW.Exosomesderivedfromhumanbonemarrowmesenchymalstemcellspromotetumorgrowthinvivo,CancerLett,2012,315(1):28-37(SCIIF:6.375) 26.XuX,QianH,ZhuW,ZhangX,YanY,WangM,XuW.IsolationofcancerstemcellsfromtransformedhumanmesenchymalstemcelllineF6,JMolMed(Berl),2010,88(11):1181-1190(SCIIF:4.686) 27.XuX,ZhangX,WangS,QianH,ZhuW,CaoH,WangM,ChenY,XuW.Isolationandcomparisonofmesenchymalstem-likecellsfromhumangastriccancerandadjacentnon-canceroustissues,JCancerResClinOncol,2011,137(3):495-504(SCIIF:3.503)

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