近期论文
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1)ZhangX*,XuW.NeutrophilsdiminishT-cellimmunitytofostergastriccancerprogression:TheroleofGM-CSF/PD-L1/PD-1signalingpathway.Gut.2017,66(11):1878-1880.(IF:16.658)
2)ZhangX*,YuanX,ShiH,WuL,QianH,XuW.Exosomesincancer:smallparticle,bigplayer.JHematolOncol.2015,8:83.(IF:6.263；ESI高被引论文前1%)
3)ZhangX*,ZhangW,YuanX,FuM,QianH,XuW.Neutrophilsincancerdevelopmentandprogression:roles,mechanisms,andimplications.IntJOncol.2016,49(3):857-867.(IF:3.025)
4)ZhangX#,*,YuanX#,ZhuW,QianH,XuW.SALL4:anemergingcancerbiomarkerandtarget.CancerLett.2015,357(1):55-62.(IF:6.375)
5)ZhangX,WangW,WangH,WangM,XuW,ZhangR.IdentificationofribosomalproteinS25(RPS25)-MDM2-p53regulatoryfeedbackloops.Oncogene.2013,32(22):2782-91.(IF:8.459)
6)ZhangX,ZhangZ,ChengJ,LiM,WangW,XuW,WangH,ZhangR.TranscriptionfactorNFAT1activatesthemdm2oncogeneindependentofp53.JBiolChem.2012,287(36):30468-76.(IF:4.573)
7)ZhangX,XuW,QianH,ZhuW,ZhangR.MesenchymalstemcellsmodifiedtoexpresslentivirusTNF-αTumstatin(45-132)inhibitthegrowthofprostatecancer.JCellMolMed.2011,15(2):433-44.(IF:4.938)
8)ZhangX,ZhangL,XuW,QianH,YeS,ZhuW,CaoH,YanY,LiW,WangM,WangW,ZhangR.ExperimentaltherapyforlungCancer:umbilicalcord-derivedmesenchymalstemcell-mediatedinterleukin-24delivery.CurrCancerDrugTargets.2013,13(1):92-102.(IF:3.707)
9)ZhuQ,ZhangX#,*,ZhangL,LiW,WuH,YuanX,MaoF,WangM,ZhuW,QianH,XuW.TheIL-6–STAT3axismediatesareciprocalcrosstalkbetweencancer-derivedmesenchymalstemcellsandneutrophilstosynergisticallypromptgastriccancerprogression.CellDeathDis.2014,5:e1295.(IF:5.965)
10)YuanX,ZhangX#,*,ZhangW,LiangW,ZhangP,ShiH,ZhangB,ShaoM,YanY,QianH,XuW*.SALL4promotesgastriccancerprogressionthroughactivatingCD44expression.Oncogenesis,2016,5(11):e268.(IF:5.021)
11)YangT,ZhangX#,WangM,ZhangJ,HuangF,CaiJ,ZhangQ,MaoF,ZhuW,QianH,XuW.ActivationofmesenchymalstemcellsbymacrophagespromptshumangastriccancergrowththroughNF-κBpathway.PLoSOne.2014,9(5):e97569.(IF:3.534)
12)WuL,ZhangX#,ZhangB,ShiH,YuanX,SunY,PanZ,QianH,XuW.ExosomesderivedfromgastriccancercellsactivateNF-κBpathwayinmacrophagestopromotecancerprogression.TumorBiol,2016,37(9):12169-12180.(IF:3.611)
13)QianH,ZhangX#,XuW,ZhuW,CaoH,ChenY,XuX,WangM,XieY,SunJ.Lentivirus-modifiedhumanumbilicalcordmesenchymalstemcellsmaintainstheirpluripotency.BiotechnolApplBiochem.2010,55(1):53-62.(IF:1.322)
14)JiR,ZhangX*,QianH,GuH,SunZ,MaoF,YanY,ChenJ,LiangZ,XuW.MiR-374mediatesthetransitionofgastriccancer-associatedmesenchymalstemcellsinanexperimentalratmodel.OncolReports,2017,38:1473-1481.(IF:2.662)
15)ZhangY,LiangW,ZhangP,ChenJ,QianH,ZhangX*,XuW.CircularRNAs:emergingcancerbiomarkersandtargets.JExpClinCancerRes.2017,36(1):152.(IF:5.189)
16)PanL,LiangW,FuM,HuangZH,ZhangW,LiX,QianH,JiangP,XuW,ZhangX*.Exosomes-mediatedtransferoflongnoncodingRNAZFAS1promotesgastriccancerprogression.JCancerResClinOncol.2017,143(6):991-1004.(IF:3.503)
17)ZhangW,ChenJ,JiR,ZhangP,YuanX,MaoF,XuW,ZhangX*,Interactionwithneutrophilspromotesthemigrationandinvasionofgastriccancercellsthroughtheinductionofepithelial-mesenchymaltransition.OncolReports,2017,38:2959-2966.(IF:2.662)
18)FuM,ZouC,PanL,LiangW,QianH,XuW,JiangP,ZhangX*.LongnoncodingRNAsindigestivesystemcancers:functionalroles,molecularmechanisms,andclinicalimplications.OncolReports,2016,36(3):1207-1218.(IF:2.662)
19)YangH,FuH,XuW,ZhangX*.Exosomalnon-codingRNAs:apromisingcancerbiomarker.ClinChemLabMed.2016,54(12):1871-1879.(IF:3.432)
20)FuH,YangH,ZhangX*,XuW.Theemergingrolesofexosomesintumor-stromainteraction.JCancerResClinOncol.2016,142(9):1897-907.(IF:3.503)
21)MaoF,WuY,TangX,KangJ,ZhangB,YanY,QianH,ZhangX*,XuW.Exosomesderivedfromhumanumbilicalcordmesenchymalstemcellsrelieveinflammatoryboweldiseaseinmice.BiomedResInt,2017,2017:5356760.(IF:2.476)
22)WangW,NagS,ZhangX,WangMH,WangH,ZhouJ,ZhangR.Ribosomalproteinsandhumandiseases:pathogenesis,molecularmechanisms,andtherapeuticimplications.MedResRev.2015,35(2):225-85.(IF:9.135)
23)ZhangB,WangM,GongA,ZhangX,WuX,ZhuY,ShiH,WuL,ZhuW,QianH,XuW.HucMSC-exosomemediated-Wnt4signalingisrequiredforcutaneouswoundhealing.StemCells.2015,33(7):2158-68.(IF:6.523)
24)ZhangB,WuX,ZhangX,SunY,YanY,ShiH,ZhuY,WuL,PanZ,ZhuW,QianH,XuW.HumanUmbilicalCordMesenchymalStemCellExosomesEnhanceAngiogenesisThroughtheWnt4/β-CateninPathway.StemCellsTranslMed.2015,4(5):513-22.(IF:3.596)
25)LiW,ZhouY,YangJ,ZhangX,ZhangH,ZhangT,ZhaoS,ZhengP,HuoJ,WuH.Gastriccancer-derivedmesenchymalstemcellspromptgastriccancerprogressionthroughinterleukin-8.JExpClinCancerRes.2015,34:52.(IF:5.189)
26)JiR,ZhangB,ZhangX,XueJ,YuanX,YanY,WangM,ZhuW,QianH,XuW.Exosomesderivedfromhumanmesenchymalstemcellsconferdrugresistanceingastriccancer.CellCycle.2015,14(15):2473-83.(IF:4.565)
27)ZhuW,HuangL,LiY,ZhangX,GuJ,YanY,XuX,WangM,QianH,XuW.Exosomesderivedfromhumanbonemarrowmesenchymalstemcellspromotetumorgrowthinvivo.CancerLett.2012,315(1):28-37.(IF:5.992；ESI高被引论文前1%)
28)LiT,YanY,WangB,QianH,ZhangX,ShenL,WangM,ZhouY,ZhuW,LiW,XuW.Exosomesderivedfromhumanumbilicalcordmesenchymalstemcellsalleviateliverfibrosis.StemCellsDev.2012,22(6):845-54.(IF:4.202；ESI高被引论文前1%)
29)ShiH,XuX,ZhangB,XuJ,PanZ,GongA,ZhangX,LiR,SunY,YanY,MaoF,QianH,XuW.3,3’-DiindolylmethanestimulatesexosomalWnt11autocrinesignallinginhumanumbilicalcordmesenchymalstemcellstoenhancewoundhealing.Theranostics.2017,7(6):1674-1688.(IF:8.854)
30)ZhangB,ShiY,GongA,PanZ,ShiH,SunY,YangH,FuH,YanY,ZhangX,WangM,ZhuW,QianH,XuW.HucMSCexosome-delivered14-3-3ζorchestratesself-controlofthewntresponseviamodulationofYAPduringcutaneousregeneration.StemCells.2016,34(10):2485-2500.(IF:7.133)
31)MaoJ,LiangZ,ZhangB,YangH,LiX,FuH,ZhangX,YanY,XuW,QianH.UBR2EnrichedinP53-/-mBMMSC-ExosomePromotedGastricCancerProgressionviaWnt/β-cateninPathway.StemCells.2017,35(11):2267-2279.(IF:5.599)
32)ZhangL,XuZ,XuX,ZhangB,WuH,WangM,ZhangX,YangT,CaiJ,YanY,MaoF,ZhuW,ShaoQ,QianH,XuW.SALL4,anovelmarkerforhumangastriccarcinogenesisandmetastasis.Oncogene.2014,33(48):5491-500.(IF:8.559)
33)WangM,ZhaoC,ShiH,ZhangB,ZhangL,ZhangX,WangS,WuX,YangT,HuangF,CaiJ,ZhuQ,ZhuW,QianH,XuW.DeregulatedmicroRNAsingastriccancertissue-derivedmesenchymalstemcells:novelbiomarkersandamechanismforgastriccancer.BrJCancer.2014,110(5):1199-210.(IF:6.176)
34)WangM,GuH,QianH,ZhuW,ZhaoC,ZhangX,TaoY,ZhangL,XuW.miR-17-5p/20aareimportantmarkersforgastriccancerandmurinedoubleminute2participatesintheirfunctionalregulation.EurJCancer.2013,49(8):2010-21.(IF:6.163)
35)WangW,ZhangX,QinJ,VorugantiS,NagSA,WangM,WangH,ZhangR.Naturalproductginsenoside25-OCH3-PPDinhibitsbreastcancergrowthandmetastasisthroughdown-regulatingMDM2.PLoSOne.2012,7(7):e41586.(IF:3.534)
36)NagS,ZhangX,SrivenugopalKS,WangMH,WangW,ZhangR.TargetingMDM2-p53interactionforcancertherapy:arewethereyet?CurrMedChem.2014,21(5):553-74.(IF:3.715)
37)QianQ,QianH,ZhangX,ZhuW,YanY,YeS,PengX,LiW,XuZ,SunL,XuW.5-Azacytidineinducescardiacdifferentiationofhumanumbilicalcord-derivedmesenchymalstemcellsbyactivatingextracellularregulatedkinase.StemCellsDev.2012,21(1):67-75.(IF:4.202)
38)PanZ,TianY,ZhangB,ZhangX,ShiH,LiangZ,WuP,LiR,YouB,YangL,MaoF,QianH,XuW.YAPsignalingingastriccancer-derivedmesenchymalstemcellsiscriticalforitspromotingroleincancerprogression.IntJOncol.2017,51(4):1055-1066.(IF:3.025)
39)XuX,ZhangX,WangS,QianH,ZhuW,CaoH,WangM,ChenY,XuW.Isolationandcomparisonofmesenchymalstem-likecellsfromhumangastriccancerandadjacentnon-canceroustissues.JCancerResClinOncol.2011,137(3):495-504.(IF:3.009)
40)GuH,JiR,ZhangX,WangM,ZhuW,QianH,ChenY,JiangP,XuW.ExosomesderivedfromhumanmesenchymalstemcellspromotegastriccancercellgrowthandmigrationviatheactivationoftheAktpathway.MolMedRep.2016,14(4):3452-8.(IF:1.554)
41)XueJ,ZhuY,SunZ,JiR,ZhangX,XuW,YuanX,ZhangB,YanY,YinL,XuH,ZhangL,ZhuW,QianH.Tumorigenichybridsbetweenmesenchymalstemcellsandgastriccancercellsenhancedcancerproliferation,migrationandstemness.BMCCancer.2015,15:793.(IF:3.362)
42)XuH,QianH,ZhuW,ZhangX,YanY,MaoF,WangM,XuH,XuW.MesenchymalstemcellsrelievefibrosisofSchistosomajaponicum-inducedmouseliverinjury.ExpBiolMed(Maywood).2012,237(5):585-92.(IF:2.226)
43)ChenY,QianH,ZhuW,ZhangX,YanY,YeS,PengX,LiW,XuW.Hepatocytegrowthfactormodificationpromotestheameliorationeffectsofhumanumbilicalcordmesenchymalstemcellsonratacutekidneyinjury.StemCellsDev.2011,20(1):103-13.(IF:4.202)
44)XuX,QianH,ZhuW,ZhangX,YanY,WangM,XuW.IsolationofcancerstemcellsfromtransformedhumanmesenchymalstemcelllineF6.JMolMed(Berl).2010,88(11):1181-90.(IF:4.739)
45)GuJ,QianH,ShenL,ZhangX,ZhuW,HuangL,YanY,MaoF,ZhaoC,ShiY,XuW.GastricCancerExosomesTriggerDifferentiationofUmbilicalCordDerivedMesenchymalStemCellstoCarcinoma-AssociatedFibroblaststhroughTGF-β/SmadPathway.PLoSOne.2012,7(12):e52465.(IF:3.534)
46)GaoS,MaoF,ZhangB,ZhangL,ZhangX,WangM,YanY,YangT，ZhangJ，ZhuW,QianH,XuW.MousebonemarrowderivedmesenchymalstemcellsinducemacrophageM2polarizationthroughtheNF-κBandSTAT3pathways.ExpBiolMed(Maywood).2014,239(3):366-75.(IF:2.226)
47)CaoH,QianH,XuW,ZhuW,ZhangX,ChenY,WangM,YanY,XieY.Mesenchymalstemcellsderivedfromhumanumbilicalcordameliorateischemia/reperfusion-inducedacuterenalfailureinrats.BiotechnolLett.2010,32(5):725-32.(IF:1.736)
48)YanY,XuW,QianH,ZhuW,MaoF,ZhangX.Tumstatin45-132-TNFalphasuppressestumourgrowththroughanti-angiogeniceffectsandcytotoxicity.BiotechnolApplBiochem.2010,56(3):119-27.(IF:1.322)
49)PengX,XuH,ZhouY,WangB,YanY,ZhangX,WangM,GaoS,ZhuW,XuW,QianH.Humanumbilicalcordmesenchymalstemcellsattenuatecisplatin-inducedacuteandchronicrenalinjury.ExpBiolMed(Maywood).2013,238(8):960-70.(IF:2.226)
50)ZhangQ,WangM,HuangF,YangT,CaiJ,ZhangX,ZhuW,QianH,XuW.H.pyloriinfection-inducedMSCdifferentiationintoCAFspromotesepithelial-mesenchymaltransitioningastricepithelialcells.IntJMolMed.2013,32(6):1465-73.(IF:1.88)
51)HuangF,WangM,YangT,CaiJ,ZhangQ,SunZ,ZhangX,ZhuW,QianH,XuW.Gastriccancer-derivedMSC-secretedPDGF-DDpromotesgastriccancerprogression.JCancerResClinOncol.2014,140(11):1835-48.(IF:3.009)
52)WangM,CaiJ,HuangF,ZhuM,ZhangQ,YangT,ZhangX,QianH,XuW.Pre-treatmentofhumanumbilicalcord-derivedmesenchymalstemcellswithinterleukin-6abolishestheirgrowth-promotingeffectongastriccancercells.IntJMolMed.2015,35(2):367-75.(IF:1.88)
53)CaiJ,WangM,ZhuM,ZhangQ,ZhangX,YanY,QianH,XuW.N-methyl-N-nitro-N'-nitrosoguanidineinducestheexpressionofCCR2inhumangastricepithelialcellspromotingCCL2-mediatedmigration.MolMedRep.2016,13(2):1083-90.(IF:1.554)
54)ZhuY,ZhangB,GongA,FuH,ZhangX,ShiH,SunY,WuL,PanZ,MaoF,ZhuW,QianH,XuW.Anti-cancerdrug3,3'-diindolylmethaneactivatesWnt4signalingtoenhancegastriccancercellstemnessandtumorigenesis.Oncotarget.2016,7(13):16311-24.(IF:5.168)
55)ZhuY,YuJ,YinL,ZhouY,SunZ,JiaH,TaoY,LiuW,ZhangB,ZhangJ,WangM,ZhangX,YanY,XueJ,GuH,MaoF,XuW,QianH.MicroRNA-146b,aSensitiveIndicatorofMesenchymalStemCellRepairofAcuteRenalInjury.StemCellsTranslMed.2016,5(10):1406-1415.(IF:4.247)
56)ZhangB,ShenL,ShiH,PanZ,WuL,YanY,ZhangX,MaoF,QianH,XuW.Exosomesfromhumanumbilicalcordmesenchymalstemcells:identification,purificationandbiologicalcharacteristics.StemCellsInt.2016,2016:1929536.(IF:3.687)
57)QianH,DingX,ZhangJ,MaoF,SunZ,JiaH,YinL,WangM,ZhangX,ZhangB,YanY,ZhuW,XuW.CancerstemnessandmetastaticpotentialofthenoveltumorcelllineK3:aninnermutatedcellofbonemarrow-derivedmesenchymalstemcells.Oncotarget.2017,8(24):39522-39533.(IF:5.168)
58)MaoF,WuY,TangX,WangJ,PanZ,ZhangP,ZhangB,YanY,ZhangX,QianH,XuW.Humanumbilicalcordmesenchymalstemcellsalleviateinflammatoryboweldiseasethroughtheregulationof15-LOX-1inmacrophages.BiotechnolLett.2017,39(6):929-938.(IF:1.736)
59)WangW,AoL,RayburnER,XuH,ZhangX,ZhangX,NagSA,WuX,WangMH,WangH,VanMeirEG,ZhangR.KCN1,anovelsyntheticsulfonamideanticanceragent:Invitroandinvivoanti-pancreaticcanceractivitiesandpreclinicalpharmacology.PLoSOne.2012,7(9):e44883.(IF:3.534)
60)CaoH,XuW,QianH,ZhuW,YanY,ZhouH,ZhangX,XuX,LiJ,ChenZ,XuX.Mesenchymalstemcell-likecellsderivedfromhumangastriccancertissues.CancerLett.2009,274(1):61-71.(IF:5.992)
主要发表中文论文（#第一作者；*通讯作者）：
1)张徐*，徐梦，刘叶，顾笑笑，钱晖，许文荣.干细胞因子Nanog在肿瘤中的研究进展[J].肿瘤防治研究,2016,43(04):295-299.
2)张徐，王梦瑶，徐捡，王勇，钱晖，许文荣*.长链非编码ＲNA在乳腺癌中的研究进展[J].临床检验杂志,2015,33(6):454-456.
3)张徐，许文荣*.肿瘤相关中性粒细胞研究进展[J].临床检验杂志,2013,31(12):929-931.
4)梁炜，潘磊，付敏，钱晖，许文荣，张徐*.LncRNA在肿瘤及微环境中的作用研究进展[J].临床检验杂志,2016,34(5):329-331.
5)袁潇，梁炜，邵孟，张斌，史惠，钱晖，许文荣*，张徐*.婆罗双树样基因4慢病毒干扰载体构建及对胃癌细胞MGC80-3转移潜能的影响[J].中华肿瘤防治研究杂志,2016,23(16):1060-1066.
6)潘磊，梁炜，付敏，钱晖，许文荣，蒋鹏程*，张徐*.长非编码RNA在消化系统肿瘤中的研究进展[J].国际肿瘤学杂志,2016,43(9):706-710.
7)朱琼芳，张文，袁潇，许文荣，张徐*.中性粒细胞促进胃癌细胞体外迁移能力[J].临床检验杂志,2016,34(8):579-583.
8)张文，张鹏，徐雪莹，许文荣，张徐*.中性粒细胞在肿瘤中的作用研究进展[J].肿瘤,2017,37(1):96-100.
9)李阳，潘磊，梁炜，张鹏，钱晖，许文荣，张志坚，蒋鹏程，张徐*.胃癌患者血清外泌体中DANCR表达检测及临床意义[J].临床检验杂志,2017,35(3):176-179.
10)黄振华，梁炜，潘磊，张鹏，付敏，钱晖，许文荣，蒋鹏程，张徐*.胃癌患者血清LINC00978表达及临床意义[J].临床检验杂志,2017,35(8):575-578.
教研项目及论文:
1)ZhangX,ShaoM,GaoL,ZhaoY,SunZ,ZhouL,YanY,ShaoQ,XuW,QianH.Acomprehensiveexperimentformolecularbiology:DeterminationofsinglenucleotidepolymorphisminhumanREV3geneusingPCR-RFLP.BiochemMolBiolEdu.2017,45(4):299-304.(IF:0.465)
2)张徐，周丽萍，孙梓暄，严永敏，钱晖.临床分子生物学检验实验教学实践和探讨[J].科教文汇，2014，277:60-61.
3)江苏省医学检验技术品牌专业建设课题，基于微课导学的分子生物学检验实验教学改革和实践(Yj201612)(2016.06-2018.05)，负责人，0.5万元
4)袁一航，张徐.江苏省大学生实践创新重点项目(2016年)，胃癌特异性LncRNA鉴定、功能分析及应用研究，指导教师，2万元
5)谷雨，张徐.江苏省大学生实践创新重点项目(2017年)，长链非编码RNAZFAS1在胃癌中的作用及机制研究，指导教师，2万元
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