徐如强 - 郑州大学 - 生命科学学院

个人简介

徐如强,教授,中国农业大学,博士；中国农业科学院,博士后(出站)。曾先后就职于河南省农业科学院、北京市农林科学院、日本国立农业生物资源研究所(NationalInstituteofAgrobiologicalSciences)、日本国际农林水产业研究中心(JapanInternationalResearchCenterforAgriculturalSciences)，以及美国肯塔基大学(UniversityofKentucky)、迈阿密大学(MiamiUniversity)、弗吉尼亚联邦大学(VirginiaCommonwealthUniversity)和普渡大学(PurdueUniversity)从事研究工作。获得国家科技进步奖1项(第三完成人)和省部级科技进步奖2项；在国内外学术期刊发表论文46篇，其中SCI收录25篇；在国际基因库注册基因5个；参加编写学术著作1部；多次受邀在国内外学术会议和科研机构作学术报告。

研究领域

研究方向: 分子生物学与植物遗传改良;信号转导机制与药物筛选。

近期论文

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1.徐如强,WattsVJ.Gαi/o偶联受体介导的腺苷酸环化酶“超敏化”研究进展.药学学报,2016(印刷中). 2.XuR,El-HageN,DeverSM.Fluorescently-labeledRNApackagingintoHIV-1particles:directexaminationofinfectivityacrosscentralnervoussystemcelltypes.JournalofVirologicalMethods,2015,224:20-29. 3.HahamYK,McLaughlinJ,WoodC,MasvekarRR,XuR,HauserKF,KnappPE.ChronicHIV-1TatandHIVreduceRbfox3/NeuN:evidenceforsex-relatedeffects.CurrentHIVResearch,2015,13(1):10-20. 4.曹廷杰,谢菁忠,吴秋红,陈永兴,王振忠,赵虹,王西成,詹克慧,徐如强,王际睿,罗明成,刘志勇.河南省近年审定小麦品种基于系谱和SNP标记的遗传多样性分析.作物学报,2015,41(2):197-206. 5.LiuM,XuR,MerrillC,HuntAG,LiQQ.Integrationofdevelopmentalandhormonalsignalsviaapolyadenylationfactorinplants.PLoSONE,2014,9(12):e115779. 6.ConleyJM,BrustTF,XuR,BurrisKD,WattsVJ.Drug-inducedsensitizationofadenylylcyclase:assaystreamliningandminiaturizationforsmallmoleculeandsiRNAscreeningapplications.JournalofVisualizedExperiments,2014,(83):e51218. 7.DeverSM,CostinBN,XuR,El-HageN,BalinangJ,SamoshkinA,O’BrienMA,McRaeMP,DiatchenkoL,KnappPE,HauserKF.Differentialexpressionofthealternatively-splicedOPRM1isoformMOR-1KinHIV-infectedSubjects.AIDS,2014,28(1):19-30. 8.ConleyJM,BrandCS,BorgardAS,PrattEPS,XuR,HockermanGH,OstromRS,DessauserCW,WattsVJ.Developmentofahigh-throughputscreeningparadigmforthediscoveryofsmallmoleculemodulatorsofadenylylcyclase:Identificationofaninhibitorofadenylylcyclase2.JournalofPharmacologyandExperimentalTherapeutics,2013,347(2):276-287. 9.XingD,WangY,XuR,YeX,YangD,LiQQ.TheregulatoryroleofPcf11-similar-4(PCFS4)inArabidopsisdevelopmentbygenome-wideinteractionswithtargetloci.BMCGenomics,2013,14:598. 10.FittingS,ScogginsKL,XuR,DeverSM,KnappPE,DeweyWL,HauserKF.MorphineefficacyisalteredinconditionalHIV-1Tattransgenicmice.EuropeanJournalofPharmacology,2012,689:96-103. 11.DeverSM#,XuR#,FittingS,KnappPE,HauserKF.DifferentialexpressionandHIV-1regulationofμopioidreceptorsplicevariantsacrosscentralnervoussystemcelltypes.JournalofNeuroVirology,2012,18(3):181-190(封面文章).[#共同第一作者] 12.FittingS,XuR,BullC,BuchSK,El-HageN,NathA,KnappPE,HauserKF.Interactiveco-morbiditybetweenopioiddrugsofabuseandHIV-1Tat:Inflammationanddisruptionsinendogenousopioidsignalingaccelerateneuronalinjuryinthestriatum.AmericanJournalofPathology,2010,177(3):1397-1410. 13.DuncanMJ,Bruce-KellerAJ,ConnerC,KnappPE,XuR,NathA,HauserKF.EffectsofchronicexpressionoftheHIV-inducedprotein,transactivatoroftranscription(Tat),oncircadianactivityrhythmsinmicewithorwithoutmorphine.AmericanJournalofPhysiology-Regulatory,IntegrativeandComparativePhysiology,2008,295:R1680-R1687. 14.Bruce-KellerAJ,Turchan-CholewoJ,SmartEJ,GeurinT,ChauhanA,ReidR,XuR,NathA,KnappPE,HauserKF.MorphinecausesrapidincreasesinglialactivationandneuronalinjuryinthestriatumofinducibleHIV-1tattransgenicmice.Glia,2008,56:1414-1427. 15.ZhangJ,AddepalliB,YunKY,HuntAG,XuR,RaoS,LiQQ,FalconeDL.ApolyadenylationfactorsubunitimplicatedinregulatingoxidativesignalinginArabidopsisthaliana.PLoSONE,2008,3(6):e2410. 16.HuntAG,XuR,AddepalliB,RaoS,ForbesKP,MeeksLR,XingDH,MoM,ZhaoHW,BandyopadhyayA,DampanaboinaL,MarionA,VonLankenC,LiQQ.ArabidopsismRNApolyadenylationmachinery:comprehensiveanalysisofprotein-proteininteractionsandgeneexpressionprofiling.BMCGenomics,2008,9:220-234. 17.XingDH,ZhaoHW,XuR,LiQQ.ArabidopsisPCFS4,ahomologueofyeastpolyadenylationfactorPcf11p,regulatesFCAalternativeprocessingandpromotesfloweringtime.PlantJournal,2008,54:899-910. 18.XuR,LiQQ.StreamlinecloningofgenesintobinaryvectorsinAgrobacteriumviatheGatewayÒTOPOvectorsystem.PlantMethods,2008,4:4. 19.XuR,ZhaoH,DinkinsRD,ChenXW,CarberryG,LiQQ.The73kDsubunitofcleavageandpolyadenylationspecificityfactor(CPSF)complexaffectreproductivedevelopmentinArabidopsis.PlantMolecularBiology,2006,61:799-815. 20.BalasubrahmanyamA#,XuR#,DattaroyT,LiBC,BassWT,LiQQ,HuntAG.Diseaseresistanceinplantsthatcarryafeedback-regulatedyeastpoly(A)bindingproteingene.PlantMolecularBiology,2006,61:383-397.[#共同第一作者] 21.DelaneyKJ,XuR,ZhangJX,LiQQ,YunKY,FalconeDL,HuntAG.CalmodulininteractswithandregulatestheRNA-bindingactivityofanArabidopsispolyadenylationfactorsubunit.PlantPhysiology,2006,140:1507-1521. 22.XuR,YeXF,LiQ.AtCPSF73-IIencodingahomologueofthe73kDasubunitofCPSFiscriticalforearlyembryodevelopment.Gene,2004,324:35-45. 23.XuR,LiQ.ARING-H2zincfingerproteinRIEisessentialforseeddevelopmentinArabidopsis.PlantMolecularBiology,2003,53:37-50(封面文章). 24.TomookaN,VaughanDA,XuR,KashiwabaK,KagaA.JapanesenativeVignageneticresources.JapanAgriculturalResearchQuarterly,2001,35(1):1-9. 25.XuR,TomookaN,VaughanDA,Doi,K.TheVignaangulariscomplex:GeneticvariationandrelationshipsrevealedbyRAPDanalysis,andtheirimplicationsforinsituconservationanddomestication.GeneticResourcesandCropEvolution,2000,47:123-134. 26.XuR,TomookaN,VaughanDA.AFLPmarkersforcharacterizingtheazukibeancomplex.CropScience,2000,40:808-815(封面文章). 27.PotokinaE,TomookaN,VaughanDA,AlexandrovaT,XuR.PhylogenyofViciasubgenusVicia(Fabaceae)basedonanalysisofRAPD’sandRFLPofPCR-amplifiedchloroplastgenes.GeneticResourcesandCropEvolution,1999,46:149-161. 28.VaughanDA，KobayashiN，XuR.Collectionofthewildrelativesofcrops1997.3.TheAzukibean(Vignaangularisvarangularis)genepoolandsoybean(Glycinmax)genepoolintheKinkiregionofHonshu,Japan,4-11thNovember.植探報,1998,14:85-97. 29.TomookaN,VaughanD,XuR,DoiK.WildrelativesofcropsconservationinJapanwithafocusonVignaspp.Introduction.植探報,1998,14:45-61. 30.徐如强,孙其信,张树榛.小麦细胞膜热稳定性的配合力与杂种优势分析.作物学报,1998,24(1):55-60. 31.徐如强,孙其信,张树榛.不同冬小麦品种对高温胁迫反应的研究.中国农业大学学报,1998,3(1):99-104. 32.徐如强,孙其信,张树榛.小麦耐热性研究现状与展望(综述).中国农业大学学报,1998,3(3):110-123. 33.徐如强,孙其信,张树榛.小麦光合作用与耐热性的关系初探.作物品种资源,1997,(1):28-29,46. 34.徐如强,孙其信,张树榛.春小麦耐热性的筛选方法与指标.华北农学报,1997,12(3):22-29. 35.徐如强,孙其信,张树榛.普通小麦品种Hope细胞膜热稳定性基因的染色体定位.遗传,1996,(4):1-3. 36.徐如强,孙其信,张树榛.不同耐热性小麦品种的籽粒灌浆特性及其对高温反应的初步研究.中国农学通报,1996,12(6):7-10. 37.徐如强,孙其信,张树榛.小麦耐热性的配合力分析.中国农学通报,1996,12(3):1-3. 38.徐如强,孙其信,张树榛.小麦耐热性的杂种优势表现.北京农业科学,1996,14(1):15-17. 39.孙其信,高立峰,徐如强.异源细胞质对小麦耐热性的遗传影响.北京农业大学学报,1994,20(4):361-367. 40.徐如强,黄铁城,张爱民.“BAU-2”诱导普通小麦雄性不育的研究I.化学杀雄效果.北京农业大学学报,1993,19(增刊):1-8. 41.徐如强,黄铁城,张爱民.“BAU-2”诱导普通小麦雄性不育的研究II.化学杀雄技术.北京农业大学学报,1993,19(增刊):9-18. 42.徐如强,黄铁城,张爱民.“BAU-2”诱导普通小麦雄性不育的研究III.化学杀雄机制.北京农业大学学报,1993,19(增刊):19-24. 43.王继华,孙其信,徐如强.K型不育系恢复系筛选及花粉败育机理比较研究.北京农业大学学报,1993,19(增刊)：91-97. 44.柳家荣,郑永战,徐如强.芝麻的耐涝性与基因型及根系活力的关系.华北农学报,1993,8(3):82-86. 45.柳家荣,郑永战,徐如强.芝麻种质营养品质研究.华北农学报,1992,7(3):110-116. 46.柳家荣,郑永战,徐如强.芝麻种质营养品质分析及优质资源筛选.中国油料,1992,(1):24-26.