个人简介
个人简介:
2011年7月到河南师范大学生命科学学院遗传微生物教研室任职。主讲本科生《普通遗传学》、《基因工程》和研究生《生物反应器工程》等课程。研究方向为动物分子遗传学,主要从事动物性别调控、以及环境毒理等研究。先后在SCI及核心以上期刊发表论文三十余篇,主持国家自然科学基金、教育厅项目、横向合作项目和校级项目5项。
主持或参加科研项目情况:
1.两种泥鳅DMRT1基因不同选择性剪接体的结构、功能及调控机制(31200923),国家自然科学基金项目,2013-2015,主持
2.大鳞副泥鳅DMRT1基因不同选择性剪接体的表达模式分析(12B180011),河南省教育厅项目,2012-2014,主持
3.两种泥鳅DMRT1基因不同选择性剪接体的克隆和表达模式分析,天津市细胞遗传与分子调控重点实验室开放基金项目,2012-2014,主持
4.泥鳅DMRT1基因不同剪接体的克隆和时空表达模式分析,河南师范大学博士科研启动费支持课题,2012-2014,主持
5.大鳞副泥鳅DMRT1基因5′侧翼区的克隆及核心启动子活性分析,河南师范大学青年科学基金项目,2012-2015,主持
研究领域
1.动物性别决定和分化;
2.水生环境毒理学;
3.动物免疫机制研究。
近期论文
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1.XiaohuaXia,RuyanWan,PeijinWang,WeiranHuo,HuiDong,QiyanDu.Toxicityofimidazolesionicliquid[C16mim]CltoHelacells.EcotoxicologyandEnvironmentalSafety.2018,162:408–414.
2.XiaohuaXia,PeijinWang,RuyanWan,WeiranHuo,ZhongjieChang.Toxiceffectsofcyhalofop-butylonembryosoftheYellowRiverCarp(Cyprinuscarpiovar.):Altersembryoshatching,developmentfailure,mortalityofembryosandapoptosis.Environmentalscienceandpollutionresearch.2018,25:24305–24315.
3.XiaohuaXia,WeiranHuo,RuyanWan,LinxiaZhang,Xiaopeixia,ZhongjieChang.MolecularcloningandexpressionanalysisofSox3duringgonadandembryonicdevelopmentinMisgurnusanguillicaudatus.InternationalJournalofDevelopmentalBiology.2017,61:565-570.
4.XiaohuaXia,WeiranHuo,RuyanWan,PeijinWang,LinxiaZhang,ZhongjieChang.Molecularcloning,characterization,andexpressionprofilesoftheSox3geneinChineseloachParamisgurnusdabryanus.Evolution&Development.2018,20:108-118.
5.XiaohuaXia,PeijinWang,RuyanWan,ZhongjieChang,QiyanDu.Progesteroneaffectssexdifferentiationandalterstranscriptionalofgenesalongcircadianrhythmsignalingandhypothalamic-pituitary-gonadalaxesinjuvenileYellowRiverCarp(Cyprinuscarpiovar.).EnvironmentalToxicology.2019,34:1255–1262.
6.XiaohuaXia,WeiranHuo,RuyanWan,PeijinWang,ZhongjieChang.Cloning,characterizationandfunctionanalysisofDAX1inChineseloach(Paramisgurnusdabryanus).Genetica.2018,146:487–496
7.XiaohuaXia,XiaopeiXia,WeiranHuo,HuiDong,LinxiaZhang,ZhongjieChang.2016,Toxiceffectsofimidaclopridonadultloach(Misgurnusanguillicaudatus).EnvironmentalToxicologyandPharmacology,45:132–139.
8.XiaohuaXia,RuyanWan,WeiranHuo,LinxiaZhang,XiaopeiXia,ZhongjieChang.MolecularcloningandmRNAexpressionpatternofSox4inParamisgurnusdabryanus.GeneExpressionPatterns.2017,25-26:109–117.
9.XiaohuaXia,RuyanWan,WeiranHuo,LinxiaZhang,XiaopeiXia,ZhongjieChang.MolecularcloningandmRNAexpressionpatternofSox4inMisgurnusanguillicaudatus.Journalofgenetics.Vol.97,No.4,September2018,pp.869–877.
10.XiaohuaXia,WeiranHuo,RuyanWan,Xiaopeixia,QiyanDu,ZhongjieChang*.Identificationofhousekeepinggenesasreferencesforquantitativereal-timeRT-PCRanalysisinMisgurnusanguillicaudatus.JournalofGenetics.2017,96(6):895-904.
11.XiaohuaXia,XiaopeiXia,WeiranHuo,HuiDong,LinxiaZhang,ZhongjieChang.2016,Toxiceffectsofimidaclopridonadultloach(Misgurnusanguillicaudatus).EnvironmentalToxicologyandPharmacology,45:132–139.(SCI)
12.XiaohuaXia,JianjunChen,LinxiaZhang,QiyanDu,JinshengSun,ZhongjieChang,2013.MolecularcloningandmRNAexpressionpatternofSox10inParamisgurnusdabryanus.MolecularBiologyReports,40(4):3123-3134.
13.XiaohuaXia,PingNan,LinxiaZhang,JinshengSun,ZhongjieChang,2013.HomologueofSox10inMisgurnusanguillicaudatus:Sequence,expressionpatternduringearlyembryogenesis.FishPhysiologyandBiochemistry,39:1341–1351.
14.XiaohuaXia,JieZhao,QiyanDu,ZhongjieChang,2011.IsolationandexpressionoftwodistinctSox8genesinmudloach(Misgurnusanguillicaudatus).BiochemicalGenetics,49(3-4):161-176.
15.RuyanWan,XiaohuaXia*,PeijinWang,WeiranHuo,HuiDong,ZhongjieChang.Toxicityofimidazolesionicliquid[C16mim]CltoHepG2cells.ToxicologyinVitro.2018,52:1–7.通讯作者
16.WeiranHuo,RuyanWan,PeijinWang,LinxiaZhang,XiaohuaXia*.Molecularcloning,characterizationofdax1geneanditsresponsetoProgesteroneinMisgurnusanguillicaudatus.DrugandChemicalToxicology.2019,42(6):624–633.通讯作者