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个人简介

1988/09-1993/07南京铁道医学院预防医学系本科 2001/09-2004/07安徽医科大学流行病与卫生统计学硕士 2005/09-2008/07安徽医科大学流行病与卫生统计学博士 2008/08-2016/11温州医科大学环境与公共卫生学院讲师、副教授 2013/04-2016/11温州医科大学附属眼视光医院临床与流行病学研究中心副教授 2013/12-2015/11约翰·霍普金斯大学流行病与生物统计学博士后 2016/12-至今温州医科大学公共卫生与管理学院预防医学系教授 2016/12-至今温州医科大学附属眼视光医院临床研究中心教授

研究领域

慢性病流行病学/代谢组学/机器学习/疾病预测模型构建与评估

1.浙江省重点研发项目,2019C03012,心血管疾病诊治新技术研究-希浦系统起博在慢性心力衰竭患者中同步化治疗的应用研究,2019/01-2022/12,250万,在研,核心参与 2.浙江省基础公益项目,LGF19H260011,基于代谢组学和机器学习技术的糖尿病视网膜病变早期识别研究,2019/01-2021/12,10万,在研,主持 3.温州医科大学附属眼视光医院院内重大创新项目,YNZD170452,动态网络生物标志物用于糖尿病视网膜病变代谢机制研究,2017/01-2020/12,30万,在研,主持 4.中华人民共和国科学技术部,2016YFC1304000,基于临床生物信息学的慢阻肺危险因素、病因和发病机制研究,2017/01-2020/12,2653万,在研,核心参与 5.温州医科大学附属眼视光医院科研启动项目,KYQD170301,基于代谢组学的糖尿病视网膜病变超早期识别研究,2016/01-2019/12,30万,在研,主持 6.温州医科大学附属眼视光医院院内重大课题,YNZD201403,慢性闭角型青光眼合并白内障患者联合手术与分阶段手术治疗方案的随机对照临床试验,2015/07-2019/6,30万,在研,核心参与 7.温州医科大学附属眼视光医院院内创新课题,YNCX201308,非对称性青光眼眼局部因素对于青光眼视神经损害的多因素研究,2014/01-2017/12,12万,在研,核心参与 8.国家自然科学基金面上项目,81260413,砷暴露对儿童DNA甲基化修饰,2013/01-2016/12,50万元,已结题,参与 9.浙江省科技厅项目,2013C33169,代谢组学技术筛选砷致健康损害敏感性标志物的应用研究,2013/01-2016/12,15万元,在研,主持,结题 10.浙江省自然科学基金项目,Y2110454,MTHFR基因多态性对叶酸降砷疗效修饰效应的实验流行病学研究,2011/01-2014/12,10万元,已结题,主持 11.卫生部省部共建项目,WKJ2012-2-018,MicroRNAlet-7d对注意缺陷障碍发病及预后关系的研究,2013/01-2015/12,15万元,已结题,参与 12.国际合作课题,ShorttermhealtheffectsofsmokingcessationandtherelationshipbetweenshorttermhealtheffectsandchronicdiseasesinChinesepopulationfrommainlandChina.,2013/01-2014/12,92万,已结题,核心参与 13.国家十一·五科技支撑计划,2009BAI77B06,心理疾患防治研究与示范,2010/01-2012/12,506万元,已结题,核心参与 14.温州市科技局面上项目,Y20090026,胃癌相关生物标志物分子流行病学研究,2009/01-2012/12,3万元,已结题,主持

近期论文

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1.WeiYP,JiaCN,LanY,HouXQ,ZuoJJ,CuiH,GuanXJ,WangY,MaoGY.SerumcholesterolpositivelyassociatedwithoxidativeDNAdamage:apropensityscore-matchedanalysis.FreeRadicRes2019;53(4):411-7.(通讯作者) 2.RenW,QiuH,YangY,ZhuX,ZhuC,MaoG,MaoS,LinY,ShenS,LiC,XieX,ShiH,JiangS,ZhaoK,ChenL,HeJ,XuL,FuY,HuX,YuY,GuY,WangK,GuoX,HeJ.RandomizedcontrolledtrialofcognitivebehaviouraltherapyfordepressiveandanxietysymptomsinChinesewomenwithbreastcancer.PsychiatryRes2019;271:52-9. 3.LiaoN,JiangH,MaoG,LiY,XueA,LanY,LinH,WangQ.Changesinmacularultrastructuralmorphologyinunilateralanisometropicamblyopia.AmJTranslRes2019;11(8):5086-95. 4.JiaC,WeiY,LanY,HouX,ZuoJ,WangT,LiJ,GuanX,YangH,MaoG.Comprehensiveanalysisofthemetabolomiccharacteristicsonthehealthlesionsinducedbychronicarsenicexposure:Ametabolomicsstudy.IntJHygEnvironHealth2019;222(3):434-45.(通讯作者) 5.HuangW,SuL,WuS,XuL,XiaoF,ZhouX,MaoG,VijayaramanP,EllenbogenKA.Long-termoutcomesofHisbundlepacinginpatientswithheartfailurewithleftbundlebranchblock.Heart2019;105(2):137-43. 6.HouX,WangD,ZuoJ,LiJ,WangT,GuoC,PengF,SuD,ZhaoL,YeZ,ZhangH,ZhengC,MaoG.DevelopmentandvalidationofaprognosticnomogramforHIV/AIDSpatientswhounderwentantiretroviraltherapy:datafromaChinapopulation-basedcohort.Ebiomedicine(inpress)2019.(通讯作者) 7.YuY,MaoG,WangJ,ZhuL,LvX,TongQ,FangY,LvY,WangG.Gutdysbiosisisassociatedwiththereducedexercisecapacityofelderlypatientswithhypertension.HypertensRes2018;41(12):1036-44. 8.QiuH,RenW,YangY,ZhuX,MaoG,MaoS,LinY,ShenS,LiC,ShiH,JiangS,HeJ,ZhaoK,FuY,HuX,GuY,WangK,GuoX,HeJ.EffectsofcognitivebehavioraltherapyfordepressiononimprovinginsomniaandqualityoflifeinChinesewomenwithbreastcancer:resultsofarandomized,controlled,multicentertrial.NeuropsychiatrDisTreat2018;14:2665-73. 9.GuoX,ChenX,WangJ,LiuZ,GaileD,WuH,YuG,MaoG,YangZ,DiZ,GuoX,CaoL,ChangP,KangB,ChenJ,GaoW,RenX.Multi-generationalimpactsofarsenicexposureongenome-wideDNAmethylationandtheimplicationsforarsenic-inducedskinlesions.EnvironInt2018;119:250-63. 10.GaoW,HuangT,YuanH,YangJ,JinQ,JiaC,MaoG,ZhaoJ.HighlysensitivedetectionandmutationalanalysisoflungcancercirculatingtumorcellsusingintegratedcombinedimmunomagneticbeadswithadropletdigitalPCRchip.Talanta2018;185:229-36. 11.WuQ,CaoY,MaoG,WangS,FangY,TongQ,HuangQ,WangB,YanJ,WangG.Effectsofforestbathingonplasmaendothelin-1inelderlypatientswithchronicheartfailure:Implicationsforadjunctivetherapy.GeriatrGerontolInt2017;17(12):2627-9. 12.MuellerNT,MaoG,BennetWL,HouriganSK,Dominguez-BelloMG,AppelLJ,WangX.Doesvaginaldeliverymitigateorstrengthentheintergenerationalassociationofoverweightandobesity?FindingsfromtheBostonBirthCohort.IntJObes(Lond)2017;41(4):497-501. 13.MaoG,NachmanRM,SunQ,ZhangX,KoehlerK,ChenZ,HongX,WangG,CarusoD,ZongG,PearsonC,JiH,BiswalS,ZuckermanB,Wills-KarpM,WangX.IndividualandJointEffectsofEarly-LifeAmbientExposureandMaternalPrepregnancyObesityonChildhoodOverweightorObesity.EnvironHealthPerspect2017;125(6):067005. 14.LinZ,VasudevanB,CiuffredaKJ,ZhouHJ,MaoGY,WangNL,LiangYB.MyopigenicActivityChangeandItsRiskFactorsinUrbanStudentsinBeijing:Three-YearReportofBeijingMyopiaProgressionStudy.OphthalmicEpidemiol2017;24(6):388-93. 15.LinZ,VasudevanB,CiuffredaKJ,ZhouHJ,MaoGY,WangNL,LiangYB.Thedifferencebetweencycloplegicandnon-cycloplegicautorefractionanditsassociationwithprogressionofrefractiveerrorinBeijingurbanchildren.OphthalmicPhysiolOpt2017;37(4):489-97. 16.JiangJH,ZhangSD,DaiML,YangJY,XieYQ,HuC,MaoGY,LuF,LiangYB.Posner-SchlossmansyndromeinWenzhou,China:aretrospectivereviewstudy.BrJOphthalmol2017;101(12):1638-42. 17.HongX,HaoK,JiH,PengS,SherwoodB,DiNarzoA,TsaiHJ,LiuX,BurdI,WangG,JiY,CarusoD,MaoG,BartellTR,ZhangZ,PearsonC,HeffnerL,CerdaS,BeatyTH,FallinMD,Lee-ParritzA,ZuckermanB,WeeksDE,WangX.Genome-wideapproachidentifiesanovelgene-maternalpre-pregnancyBMIinteractiononpretermbirth.NatCommun2017;8:15608. 18.ChenX,GuoX,HeP,NieJ,YanX,ZhuJ,ZhangL,MaoG,WuH,LiuZ,AgaD,XuP,SmithM,RenX.InteractiveInfluenceofN6AMT1andAs3MTGeneticVariationsonArsenicMetabolisminthePopulationofInnerMongolia,China.ToxicolSci2017;155(1):124-34. 19.ZhaoT,JinY,MaoG,WeiY,WuG,YeX,ZhouY,YuanG,GaoL,HongY,ChenY,HongC,ZhouH,SuD,QinZ,LuL.CYFRA21-1isanearlypredictorofchemotherapeuticeffectivenessinadvancednonsmallcelllungcancer:Anobservationalstudy.Medicine(Baltimore)2016;95(52):e5748. 20.WangG,JohnsonS,GongY,PolkS,DivallS,RadovickS,MoonM,PaigeD,HongX,CarusoD,ChenZ,MallowE,WalkerSO,MaoG,PearsonC,WangMC,ZuckermanB,ChengTL,WangX.WeightGaininInfancyandOverweightorObesityinChildhoodacrosstheGestationalSpectrum:aProspectiveBirthCohortStudy.SciRep2016;6:29867. 21.WalkerSO,MaoG,CarusoD,HongX,PongracicJA,WangX.CardiovascularRiskFactorsinParentsofFood-AllergicChildren.Medicine(Baltimore)2016;95(15):e3156.(共同第1作者) 22.NachmanRM,MaoG,ZhangX,HongX,ChenZ,SoriaCS,HeH,WangG,CarusoD,PearsonC,BiswalS,ZuckermanB,Wills-KarpM,WangX.IntrauterineInflammationandMaternalExposuretoAmbientPM2.5duringPreconceptionandSpecificPeriodsofPregnancy:TheBostonBirthCohort.EnvironHealthPerspect2016;124(10):1608-15.(共同第1作者) 23.LinZ,VasudevanB,MaoGY,CiuffredaKJ,JhanjiV,LiXX,ZhouHJ,WangNL,LiangYB.TheinfluenceofnearworkonmyopicrefractivechangeinurbanstudentsinBeijing:athree-yearfollow-upreport.GraefesArchClinExpOphthalmol2016;254(11):2247-55. 24.LinZ,VasudevanB,FangSJ,JhanjiV,MaoGY,HanW,GaoTY,CiuffredaKJ,LiangYB.Eyeexercisesofacupoints:theirimpactonmyopiaandvisualsymptomsinChineseruralchildren.BMCComplementAlternMed2016;16:349. 25.HongX,Ladd-AcostaC,HaoK,SherwoodB,JiH,KeetCA,KumarR,CarusoD,LiuX,WangG,ChenZ,JiY,MaoG,WalkerSO,BartellTR,JiZ,SunY,TsaiHJ,PongracicJA,WeeksDE,WangX.Epigenome-wideassociationstudylinkssite-specificDNAmethylationchangeswithcow'smilkallergy.JAllergyClinImmunol2016;138(3):908-11e9. 26.LinZ,MaoGY,VasudevanB,JinZB,CiuffredaKJ,JhanjiV,ZhouHJ,WangNL,LiangYB.TheAssociationbetweenMaternalReproductiveAgeandProgressionofRefractiveErrorinUrbanStudentsinBeijing.PLoSOne2015;10(9):e0139383. 27.LiJ,JiangS,ZhangY,TangG,WangY,MaoG,LiZ,XuX,WangB,HuoY.H-typehypertensionandriskofstrokeinchineseadults:Aprospective,nestedcase-controlstudy.JTranslIntMed2015;3(4):171-8. 28.GuoX,CuiH,ZhangH,GuanX,ZhangZ,JiaC,WuJ,YangH,QiuW,ZhangC,YangZ,ChenZ,MaoG.ProtectiveEffectofFolicAcidonOxidativeDNADamage:ARandomized,Double-Blind,andPlaceboControlledClinicalTrial.Medicine(Baltimore)2015;94(45):e1872.(通讯作者) 29.ZhouLL,ZhangX,BaoQQ,LiuRP,GongMY,MaoGY,ZouM,ZhuJH.AssociationanalysisofPARK16-18variantsandParkinson'sdiseaseinaChinesepopulation.JClinNeurosci2014;21(6):1029-32. 30.YangH,MaoG,ZhangH,ZhangC,QiuW,GuoX.[Associationbetweendyslipidemiaand8-OHdG/Cramongapopulationexposedtochronicarsenic].ZhonghuaLiuXingBingXueZaZhi2014;35(7):802-5. 31.WangY,HuangXF,YangMM,CaiWJ,ZhengMQ,MaoG,PangCP,JinZB.CFI-rs7356506isageneticprotectivefactorforacuteanterioruveitisinChinesepatients.BrJOphthalmol2014;98(11):1592-6. 32.LuoP,WuJ,MaoGY.Pediclescrewfixationinminimallyinvasivetransforaminallumbarinterbodyfusion.NeurosurgFocus2014;36(6):1. 33.LinZ,VasudevanB,JhanjiV,MaoGY,GaoTY,WangFH,RongSS,CiuffredaKJ,LiangYB.Nearwork,outdooractivity,andtheirassociationwithrefractiveerror.OptomVisSci2014;91(4):376-82. 34.LinZ,GaoTY,VasudevanB,JhanjiV,CiuffredaKJ,ZhangP,LiL,MaoGY,WangNL,LiangYB.GenerationaldifferenceofrefractiveerrorandriskfactorsintheHandanOffspringMyopiaStudy.InvestOphthalmolVisSci2014;55(9):5711-7. 35.ZhangC,MaoG,HeS,YangZ,YangW,ZhangX,QiuW,TaN,CaoL,YangH,GuoX.Relationshipbetweenlong-termexposuretolow-levelarsenicindrinkingwaterandtheprevalenceofabnormalbloodpressure.JHazardMater2013;262:1154-8.(共同第1作者) 36.HuH,CuiH,HanW,YeL,QiuW,YangH,ZhangC,GuoX,MaoG.Acutoffpointforarterialstiffnessusingthecardio-anklevascularindexbasedoncarotidarteriosclerosis.HypertensRes2013;36(4):334-41.(通讯作者) 37.JiangZ,ShenM,MaoG,ChenD,WangJ,QuJ,LuF.AssociationbetweencornealbiomechanicalpropertiesandmyopiainChinesesubjects.Eye(Lond)2011;25(8):1083-9. 38.MaoG,GuoX,KangR,RenC,YangZ,SunY,ZhangC,ZhangX,ZhangH,YangW.PrevalenceofdisabilityinanarsenicexposureareainInnerMongolia,China.Chemosphere2010;80(9):978-81. 39.ZhangX,MaoGY,LiuHP,XuXP.[InfluenceofbloodpressureloweringtreatmentonIPSS,Qmaxinoldandmiddle-agedmalepatientswithessentialhypertension].ZhonghuaNanKeXue2009;15(7):632-5. 40.LiuH,LiuP,MaoG,ChenG,WangB,QinX,NaY,LiuZ,WangX,XuX.Efficacyofcombinedamlodipine/terazosintherapyinmalehypertensivepatientswithlowerurinarytractsymptoms:arandomized,double-blindclinicaltrial.Urology2009;74(1):130-6. 41.FuJ,TangHQ,QinXH,MaoGY,TangGF.[Efficacyofenalaprilcombinedwithfolicacidinloweringbloodpressureandplasmahomocysteinelevel].ZhonghuaYiXueZaZhi2009;89(31):2179-83. 42.MaoG,HongX,XingH,LiuP,LiuH,YuY,ZhangS,JiangS,WangX,XuX.Efficacyoffolicacidandenalaprilcombinedtherapyonreductionofbloodpressureandplasmaglucose:amulticenter,randomized,double-blind,parallel-controlled,clinicaltrial.Nutrition2008;24(11-12):1088-96. 43.LiuH,ZhangS,JiangS,MaoG,HongX,YuY,ZhangY,TangG,XingH,XuX.Renin-angiotensin-aldosteronesystemgenepolymorphismsandantihypertensiveresponsetoirbesartaninChinesehypertensives.MethodsFindExpClinPharmacol2008;30(4):307-12. 44.FengY,MaoG,RenX,XingH,TangG,LiQ,LiX,SunL,YangJ,MaW,WangX,XuX.Ser1369AlavariantinsulfonylureareceptorgeneABCC8isassociatedwithantidiabeticefficacyofgliclazideinChinesetype2diabeticpatients.DiabetesCare2008;31(10):1939-44.(共同第1作者) 45.WangX,QinX,DemirtasH,LiJ,MaoG,HuoY,SunN,LiuL,XuX.Efficacyoffolicacidsupplementationinstrokeprevention:ameta-analysis.Lancet2007;369(9576):1876-82. 46.ChenG,JiangS,MaoG,ZhangS,HongX,TangG,LiZ,LiuX,ZhangY,XingH,WangB,YuY,XuX.CYP2C9Ile359Leupolymorphism,plasmairbesartanconcentrationandacutebloodpressurereductionsinresponsetoirbesartantreatmentinChinesehypertensivepatients.MethodsFindExpClinPharmacol2006;28(1):19-24. 47.ZhangS,MaoG,ZhangY,TangG,WenY,HongX,JiangS,YuY,XuX.AssociationbetweenhumanatrialnatriureticpeptideVal7Metpolymorphismandbaselinebloodpressure,plasmatroughirbesartanconcentrations,andtheantihypertensiveefficacyofirbesartaninruralChinesepatientswithessentialhypertension.ClinTher2005;27(11):1774-84. 48.JiangS,MaoG,ZhangS,HongX,TangG,LiZ,LiuX,ZhangY,WangB,XuX,WangX.Individualandjointassociationofalpha1A-adrenergicreceptorArg347CyspolymorphismandplasmairbesartanconcentrationwithbloodpressuretherapeuticresponseinChinesehypertensivesubjects.ClinPharmacolTher2005;78(3):239-48. 49.HongX,ZhangS,MaoG,JiangS,ZhangY,YuY,TangG,XingH,XuX.CYP2C9*3allelicvariantisassociatedwithmetabolismofirbesartaninChinesepopulation.EurJClinPharmacol2005;61(9):627-34.

学术兼职

全国工业统计学教学研究会健康医疗大数据学会常务理事 中国医药教育协会健康管理专业委员会常务委员 中国医疗保健国际交流促进会循证医学分会临床研究学组副组长 中国医师协会循证医学专业委员会循证眼科分会委员 中国卫生信息学会卫生统计教育专业委员会委员 中国卫生信息学会统计理论与方法专业委员会委员 中国医药教育协会医药统计专业委员会委员 浙江省抗癌协会肿瘤流行病学专业委员会委员 浙江省预防医学会流行病学专业委员会委员 安徽省预防医学会卫生统计专业委员会常务委员

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