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研究领域

1. 硅酸盐生物活性骨水泥的基础和应用研究 研究重点:新型生物活性骨修复自固化材料的性能调控及其成骨机制的研究及相关产品的开发 2. 金属-无机复合生物材料 研究重点:基于可降解金属和无机生物活性颗粒的新型复合材料的制备方法、性能调控及生物功能机理 3. 金属材料表面生物功能化结构构建 研究重点:基于电化学方法的金属生物材料表面功能化涂层的构建、调控及其生物学功能研究

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Z. Huan, J. Chang. Novel bioactive composite bone cements based on β-tricalcium phosphate-monocalcium phosphate monohydrate composite cement system. Acta Biomaterialia 2009;5(4):1253-1264. Z. Huan, J. Chang. Study on a novel tricalcium silicate/monocalcium phosphate monohydrate composite bone cement. Journal of Biomedical Materials Research. Part B: Applied Biomaterials 2007;82:352-359. Z. Huan, J. Chang, X. Huang. Study on the self-setting properties and in vitro bioactivity of Ca2SiO4/CaSO4·1/2H2O composite bone cement. Journal of Biomedical Materials Research. Part B: Applied Biomaterials 2008;87(2):387-394. Z. Huan, M.A. Leeflang, J. Zhou, J. Duszczyk. In vitro degradation behavior and bioactivity of magnesium-Bioglass® composites for orthopedic applications. Journal of Biomedical Materials Research Part B, 2012;100B:437-446. Z. Huan, L.E. Fratila-Apachitei, I. Apachitei, J. Duszczyk. Porous TiO2 surface formed on nickel-titanium alloy by plasma electrolytic oxidation: a prospective polymer-free reservoir for drug eluting stent applications. Journal of Biomedical Materials Research Part B, 2013,101B:700-708. Z. Huan, J. Chang, J. Zhou. Low-temperature fabrication of macroporous scaffolds through foaming and hydration of tricalcium silicate paste and their bioactivity. Journal of Materials Science 2010;45(4):961-968. Z. Huan, J. Chang. Study on physicochemical properties and in vitro bioactivity of tricalcium silicate-calcium carbonate composite bone cement. Journal of Materials Science: Materials in Medicine 2008;19(8):2913-2918. Z. Huan, J. Chang. Calcium-phosphate-silicate composite bone cement: self-setting properties and in vitro bioactivity. Journal of Materials Science: Materials in Medicine 2009;20(4):833-841. Z. Huan, M.A. Leeflang, J. Zhou, L.E. Fratila-Apachitei and J. Duszczyk. In vitro degradation behavior and cytocompatibility of Mg-Zn-Zr alloys. Journal of Materials Science: Materials in Medicine 2010;21(9):2623-2635. Z. Huan, J. Chang. Self-setting properties and in vitro bioactivity of the calcium sulfate hemihydrate/tricalcium silicate composite bone cements. Acta Biomaterialia 2007;3:952-960. Z. Huan, J. Zhou, J. Duszczyk. Magnesium-based composites with improved in vitro surface biocompatibility. Journal of Materials Science: Materials in Medicine 2010;21(12):3163-3169. Z. Huan, L.E. Fratila-Apachitei, I. Apachitei, J. Duszczyk. Porous NiTi surfaces for biomedical applications. Applied Surface Science 2012;258:5244-5249. Z. Huan, L.E. Fratila-Apachitei, I. Apachitei, J. Duszczyk. Effect of aging treatment on the in vitro nickel release from porous oxide layers on NiTi. Applied Surface Science, 2013;274:266-272. Z. Huan, J. Chang. Effect of sodium carbonate as liquid phase on self-setting properties of tricalcium silicate bone cement. Journal of Biomaterials Applications 2008;23(3):247-262. Z. Huan, M.A. Leeflang, J. Zhou, J. Duszczyk. ZK30-bioactive glass composites for orthopedic applications: A comparative study on fabrication method and characteristics. Materials Science and Engineering: B, 2011;176:1644-1652. Z. Huan, L.E. Fratila-Apachitei, I. Apachitei, J. Duszczyk. Characterization of porous TiO2 surfaces formed on 316L stainless steel by plasma electrolytic oxidation for stent application. Journal of Functional Biomaterials, 2012;3:349-360. Z. Huan, L.E. Fratila-Apachitei, I. Apachitei, J. Duszczyk. Synthesis and characterization of hybrid micro/nanostructured NiTi surfaces by a combination of etching and anodizing. Nanotechnology 2014;25:055602.

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