个人简介
Walter Lempert is a Professor with joint appointment in the Departments of Mechanical Engineering and Chemistry. He received his Ph.D. in Physical Chemistry from the University of Utah in 1981. Prior to his arrival at OSU in 1997 he spent two years as an NRC Post-doctoral Fellow at the National Bureau of Standards, five years at NASA, and 9 years at Princeton University. Current research interests center on the development and application of optical techniques for probing energy transfer and nonequilibrium plasma phenomena. He is currently a member and past chair of the American Institute of Aeronautic and Astronautics Aerodynamic Measurement Technology Technical Committee.
研究领域
Physical/Chemical Physics
Biophysical Chemistry, NMR Spectroscopy, Protein Structure & Dynamics, Molecular Self-Assembly
Our research is focused on the development of multidimensional magic-angle spinning solid-state NMR techniques, and their application to the detailed analysis of molecular structure, conformational dynamics and intermolecular interactions of otherwise intractable biological macromolecules that are of fundamental importance to human health. We also develop and apply multidimensional solution-state NMR methods and employ computational, biophysical, biochemical and molecular biology approaches for certain aspects of our work. Current research directions include:
• Development of solid-state NMR methods for probing long range structure in proteins via the incorporation of covalently-bound paramagnetic tags
• Design of NMR pulse sequences for site-resolved measurement of structural and dynamic data in proteins with improved precision and accuracy
• Elucidation of the structural basis of protein conformational inheritance in amyloid and prion diseases
• Characterization of chromatin structure and dynamics
• Structural analysis of biologically-inspired synthetic nanomaterials
• Elucidation of the molecular level interactions between small molecule ligands and supramolecular amyloid peptide and protein assemblies
Our work is currently funded by the National Science Foundation, the National Institutes of Health, the Camille & Henry Dreyfus Foundation, Eli Lilly and the Evans Disease Endowment Fund at Ohio State.
Dr. Jaroniec will be taking graduate students this year and welcomes inquiries about openings in his group.
近期论文
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Y. Zuzeek, S. Bowman, I. Choi, I.V. Adamovich, and W.R. Lempert, "Pure Rotational CARS Studies of Thermal Energy Release and Ignition in Nanosecond Repetitively Pulsed Hydrogen-Air Plasmas," PROC-D-10-0526, To appear in Proceedings of the Combustion Institute, vol 33, 2011.
Y. Zuzeek, I. Choi, M. Uddi, I.V. Adamovich, and W. R. Lempert, "Pure Rotational CARS Thermometry Studies of Low Temperature Oxidation Kinetics in Air and Ethylene-Air Nanosecond Pulse Discharge Plasmas," J. Phys. D: Appl. Phys 43, p. 124001, 2010.
N. Jiang, M. Webster, and W.R. Lempert, "New advances in generation of high repetition rate burst mode laser output," Applied Optics 48 No 4, pp. B23-31, 2009.
M. Uddi, N. Jiang, E. Mintusov, I. V. Adamovich, and W. R. Lempert "Atomic Oxygen Measurements in Air and Air/Fuel Nanosecond Pulse Discharges by Two Photon Laser Induced Fluorescence, PROCI-D-07-00123R1, Proceedings of the Combustion Institute, vol. 32, pp. 929-936, 2009.
T. Ahn, I. Adamovich, and W. Lempert, "Stimulated Raman scattering measurements of V-V transfer in hydrogen," Chemical Physics, vol. 355, pp. 55-68, 2007.
K Frederickson, W. Lee, P. Palm, I.V. Adamovich, J. W. Rich, and W.R. Lempert, "Mitigation of electron attachment to oxygen in high pressure air plasmas by vibrational excitation," J. Appl Phys 101, p. 093302, 2007.