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研究领域

(1)生物材料的生物相容性研究和(2)心血管组织工程研究。

近期论文

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Zhai W, Chang J, Lin K, Wang J, Zhao Q, Sun X. Crosslinking of decellularized porcine heart valve by procyanidins. Biomaterials, 2006(27):3684-90. Zhai W, Chang J, Lu X. Procyanidins crosslinked heart valve matrix: Anti-calcification effect. Journal of Biomedical Materials Research Part B: Appl Biomater, 2009(90B):913–921,. Zhai W, Lu X, Chang J, Zhou Y, Zhang H. Quercetin crosslinked porcine heart valve matrix: mechanical property, stability, anti-calcification and cytocompatibility. Acta Biomaterialia,. 2010(6):389–395,. LüX, Zhai W (co-First author), Zhou Y, Zhou Y, Zhang H, Chang J. Crosslinking effect of Nordihydroguaiaretic acid (NDGA) on decellularized heart valve scaffold for tissue engineering, J. Mater Sci:Mater Med, 2010(21):473–480,. Zhai W, Jia C, Zhao H, Xu Y. Procyanidins inhibit tumor angiogenesis by crosslinking extracellular matrix. Chin J Cancer Res, 2011,23(2):99-106. 翟万银,吴蕾,贾春平,邵建波,徐元森. 肿瘤微血管芯片的制备及其在通透性检测方面的应用. 功能材料与器件学报, 2011,. 翟万银,周双雯,贾春萍,徐元森. 藤黄酸抗肿瘤细胞生物学机制研究进展. 细胞生物学学报, 2009(31):481-485. Zhai W, Jia C, Lou X, Jin Q, Zhao J, Xu Y. Enhanced antitumor activity of Irinotecan combined with gambogic acid on NSCLC. 21st IUBMB and 12st FAOBMB International Congress of Biochemistry and Molecular Biology, August 2-7, 2009, Shanghai, China. Abstract, D-3-017. p158. Zhai W, Lu H, Chen L, Lin X, Huang Y, Dai K, Naoki K, Chen G, Chang J. Akermanite, a silicate bioceramic, stimulates in vitro and in vivo angiogenesis. European Cell and Material Journal, Under review. Zhai W, He C, Wu L, Zhou Y, Guo L, Chen Y, Chen H, Chang J. Degradation of hollow mesoporous silica nanoparticles (HMSN) in human umbilical vein endothelial cells. Nanomedicine: Nanotechnology Biology Medicine, Under review. Zhai W, Lu H, Chen L, Lin X, Huang Y, Dai K, Naoki K, Chen G, Chang J. Implications from comparative study on Si-containing ceramics and β-TCP: the key role of Si in in vitro cell proliferation, osteo-differentiation and angiogenesis. Biomaterials, Submitted. Zhai W, Chang J. Procyanidins-crosslinked porcine heart valve matrix: mechanical characteristics, stability and biocompatibility. Oral, 2006.11. Zhai W, Chang J. Crosslinking-decellularized valvular ECM for bioprostheses using procyanidins. Chinese Biomaterials Congress, Chengdu, Oral, 2010.4. 何常亮, 翟万银(共通讯作者),张红霞, 常江,张红峰,郭利民,陈航榕. 中空介孔硅球对血管内皮细胞的细胞毒性.华东师范大学学报(自然科学板),2011(2):142-151 Xie Y, Zhai W, Chen L, Chang J, Zheng X and Ding C. Preparation and in vitro evaluation of plasma-sprayed Mg2SiO4 coating on titanium alloy. Acta Biomaterialia, 2009(5):2331-2337 Zhang M, Zhai W, Lin K, Pan H, Lu W, Chang J. Synthesis, in-vitro hydroxyapatite forming ability, and cytocompatibility of strontium silicate powders. Journal of Biomedical Materials Research Part B (JBMR:B), Applied Biomaterials, Inpress. Wu C, Chang J, Zhai W, Ni S, Wang J. Porous akermanite scaffolds for bone tissue engineering: Preparation, characterization, and in vitro studies. Journal of Biomedical Materials Research Part B: Applied Biomaterials, 2006(78B): 47-55. Zhao L, Chang J and Zhai W. Preparation and HL-7702 cell functionality of titania/chitosan composite scaffolds. J Mater Sci: Mater Med, 2009(20):949–957 Zhao W, Chang J, Zhai W. Self-setting properties and in vitro bioactivity of Ca3SiO5/CaSO4 1/2H2o composite cement. Journal of Biomedical Materials Research Part A, 2008(85A):336-344. Wu C, Chang J, Zhai W and Ni S. A novel bioactive porous bredigite (Ca7MgSi4O16) scaffold with biomimetic apatite layer for bone tissue engineering.Journal of Materials Science: Materials in Medicine, 2007(8): 857-864.

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