个人简介
刘文静,女,博士,副研究员。2014年毕业于香港中文大学并获得博士学位。博士期间主要从事肾脏损伤修复机制研究。毕业后继续在夏银教授实验室从事博士后研究。2015年完成博士后课题后应聘至云南大学医学院工作。现主要从事肾脏疾病病理机制的研究,主持国家自然科学基金、省基金项目3项,参加国家基金、省级项目3项。
近期论文
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(1)LiuWJ#,ChenBB#,etal.RGMbprotectsagainstacutekidneyinjurybyinhibitingtubularcellnecroptosisviaanMLKL-dependentmechanism.ProcNatlAcadSciUSA,2018,115:1475-1484.
(2)ChenF#,HuQ#,......,LiuWJ*.Follistatin-likeprotein1increasestransepithelialresistanceinkidneyepithelialcellsthroughAktsignaling.MolMedRep,2017,16(4):4341-4347.
(3)ChenXJ#,LiuWJ#,etal.AmeliorativeeffectsofCompoundKandginsenosideRh1onnon-alcoholicfattyliverdiseaseinrats.,SciRep.,2017,7:41144.doi:10.1038/srep41144.
(4)LiuWJ,etal.Dragon(repulsiveguidancemoleculeRGMb)inhibitsE-cadherinexpressionandinducesapoptosisinrenaltubularepithelialcells.,JBiolChem,2013,288(44):31528-31539.
(5)LiuWJ#,MaLQ#,etal.InhibitionofhepaticglycogensynthesisbyhyperhomocysteinemiamediatedbyTRB3.,AmJPathol,2011,178(4):1489-1499.
(6)ZouT#,LiuWJ#,etal.TRB3mediateshomocysteine-inducedinhibitionofendothelialcellproliferation.,JCellPhysiol,2011,226(11):2782-2789.
(7)HuangHH……,LiuWJ,etal.Lethal(3)malignantbraintumorlike2(L3MBTL2)proteinprotectsagainstkidneyinjurybyinhibitingtheDNAdamage-p53-apoptosispathwayinrenaltubularcells.KidneyInt,2017.
(8)MengCL,LiuWJ,etal.RepulsiveGuidanceMoleculeb(RGMb)IsDispensableforNormalGonadalFunctioninMice.,BiolReprod,2016,94(4):78.
(9)ZhaoYS,……,LiuWJ,etal.IL-1betainhibitsbeta-KlothoexpressionandFGF19signalinginhepatocytes.,AmJPhysiolEndocrinolMetab,2016,310(4):E289-E300.
(10)WuXG,……,LiuWJ,etal.HFEinteractswiththeBMPtypeIreceptorALK3toregulatehepcidinexpression.,Blood,2014,124(8):1335-1343#co-firstauthor,*correspondingauthor