赵沛基 - 云南大学 - 生命科学学院

个人简介

个人简历 1.1993.09~1997.07云南大学生物系生物技术专业，获理学学士学位； 2.2001.09~2004.07中国科学院昆明植物研究所，获理学硕士学位； 3.2005.09~2008.07中国科学院昆明植物研究所，获理学博士学位； 4.1997.07~2003.07中国科学院昆明植物研究所，研究实习员； 5.2003.07~2007.12中国科学院昆明植物研究所，助理研究员； 6.2008.01~2016.04中国科学院昆明植物研究所，副研究员； 7.2012.09~2013.03美国TheUniversityofNebraska–Lincoln化学系,访问学者； 8.2009.01硕士研究生导师； 9.2016.5~2016.11,云南大学省部共建云南生物资源保护与利用国家重点实验室，副研究员； 10.2016.12~至今,云南大学省部共建云南生物资源保护与利用国家重点实验室，研究员

研究领域

围绕“微生物代谢产物生物合成”研究方向，运用天然产物化学、生化与分子生物学等学科知识与实验技术，开展微生物次生代谢产物的发现、生物合成及其调控机制的研究： 1.微生物来源活性天然产物的分离鉴定； 2.活性天然产物的生物合成。

近期论文

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1.Pei-JiZhao*,Yan-LongYang,LiangchenDu,Ji-KaiLiu,YingZeng*.Elucidatingthebiosyntheticpathwayforvibralactone,anovelpancreaticlipaseinhibitorwithafusedbicyclicβ-lactone.AngewandteChemie-InternationalEdition.2013,52(8):2298-2302. 2.YanLia,Pei-JiZhaoa,(aCo-author)Qian-JinKang,JuanMa,Lin-QuanBai*,Zi-XinDeng.DualcarbamoylationsonthepolyketideandglycosylmoietybyAsm21resultinextendedansamitocinbiosynthesis.Chemistry&Biology.2011,18(12):1571-1580. 3.PeijiZhao,LinquanBai*,JuanMa,YingZeng,LeiLi,YirongZhang,ChunhuaLu,HuanqinDai,ZhaoxianWu,YaoyaoLi,XuanWu,GangChen,XiaojiangHao,YuemaoShen*,ZixinDeng,HeinzG.Floss.AmideN-glycosylationbyAsm25,anN-glycosyltransferaseofansamitocins.Chemistry&Biology.2008,15,863-874. 4.Yin-HeYang,Xiao-LiFu,Liang-QunLi,YingZeng,Cheng-YunLi,Yi-NengHe,Pei-JiZhao*.NaphthomycinsL−N,AnsamycinAntibioticsfromStreptomycessp.CS.JournalofNaturalProducts.2012,75,1409-1413. 5.Pei-JiZhao,SuoGao,Li-MingFan,Jing-LeiNie,Hong-PingHe,YingZeng,Yue-MaoShen,Xiao-JiangHao*.ApproachtotheBiosynthesisofAtisine-typeDiterpenoidAlkaloids.JournalofNaturalProducts.2009,72(4):645-659. 6.Fei-XueYu,ZheLi,YaoChen,Yin-HeYang,Guo-HongLi,Pei-JiZhao*.FournewsteroidsfromtheendophyticfungusChaetomiumsp.M453derivedofChineseherbalmedicineHuperziaserrata.Fitoterapia,2017,117:41–46. 7.Fei-XueYu,YaoChen,Yin-HeYang,Pei-JiZhao*.Fournewdimericspiro-azaplilonederivativescochliodonesE-HfromtheentophyticfungusChaetomiumsp.M336.PhytochemistryLetters,2016,16,263-267. 8.JingLi,JinXie,Yin-HeYang,Xiao-LianLi,YingZeng,Pei-JiZhao*.PestalpolyolsA–D,cytotoxicpolyketidesfromPestalotiopsissp.cr013.PlantaMedica,2015,81:1285-1289. 9.Yan-MeiChen,Yin-HeYang,Xiao-NianLi,ChengZouandPei-JiZhao*.DiterpenoidsfromtheEndophyticFungusBotryosphaeriasp.P483oftheChineseHerbalMedicineHuperziaserrate.Molecules.2015,20,16924-16932. 10.JinXie,JingLi,Yin-HeYang,Yu-HuiChen,Pei-JiZhao*.TwonewambuicacidanalogsfromPestalotiopsissp.cr013.PhytochemistryLetters,2014,10:291-294. 11.JuanMa,Yue-MaoShen,YingZeng,Pei-JiZhao*.TwoNewN-(O-Carbamoylglucopyranosyl)-N-dimethylansamitocinsfromActinosynnemapretiosum.HelveticaChimicaActa.2012,95(9):1630–1636. 12.Jun-TianLi,Xiao-LiFu,ChunTan,YingZeng,QiWang，Pei-JiZhao*.TwonewchromanderivationsfromendophyticPenicilliumsp.DCS523.Molecules.2011,16,686-693. 13.Xiao-MeiZhang,Guo-HongLi,JuanMa,YingZeng,Wei-GuangMa,Pei-JiZhao*.EndophyticfungusTrichotheciumroseumLZ93antagonizingpathogenicfungiInVitroanditssecondarymetabolites.JournalofMicrobiology.2010,48(6):784-790.