个人简介
1991-1995河北大学环境生物学专业学士
1998-1998中科院昆明动物研究所动物学专业硕士
1998-2001中科院环境生态研究中心环境生化专业博士
2002-2004美国马里兰大学分子遗传学专业博士后
2004-2009美国范德堡大学癌症研究中心研究科学家
2010-至今云南大学生化与分子生物学教授
研究领域
本实验室关注肿瘤中的相关调控机理，以细胞株及临床病理样品为材料，集中关注Bcl-2家族在细胞凋亡及自噬中的调控作用及与线粒体代谢的关系。
近期论文
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LeiDing,HuanGu,ZhenweiLan,QingchunLei,WenxueWang,JieLin,MinYuandQinghuaCui*2019.Down-regulationofcyclooxygenase-1stimulatesmitochondrialapoptosisthroughNF-kBsignalingpathwayinColorectalCancerCells.OncologyReports,41:559-569.
2.LeiDing†,ZhenweiLan†,XianhuiXiong,HongshunAo,YingtingFeng,HuanGu,MinYu,QinghuaCui*2018.ThedualroleofmicroRNAsincolorectalcancerprogression.Int.J.Mol.Sci..19(9):2791
3.KunYAO,Xu-fengFU,XingDU,YanLI,Shan-shanYANG,MinYU,Qing-huaCUI*.2018.PGC-1αcoordinateswithBcl-2tocontrolthecellcycleinU251cellsthroughreducingROS.JZUSB,19(6):415-424
4.Da-JianHe,LingWang,Zhi-BiZhang,KunGuo,Jing-ZhengLi,Xie-ChaoHe,Qing-HuaCui*,PingZheng*.2018.MaternalgeneOoepmayparticipateinhomologousrecombination-mediatedDNAdouble-strandbreakrepairinmouseoocytes.Zoo.Res.39(6):1-10.
5.RanWei,QinYang,BingHan,YanLi,KunYao,ZexiChen,JiaqiZhou,QinghuaCui*.2017.MicroRNA-375inhibitscolorectalcancercellsproliferationbydownregulatingJAK2/STAT3andMAP3K8/ERKsignalingpathways.OncotargetDOI:10.18632
6.XingDu,XufengFu,KunYao,zhenweiLan,HuiXu,QinghuaCui*,ElizabethYang*.2017.Bcl-2delayscellcyclethroughmitochondrialATPandROS.CellCycle.16(7):707-713
7.Xu-fengFu,KunYao,XingDu,YanLi,Xiu-yuYang,MinYu,Mei-zhangLi,Qing-huaCui*.2016.PGC-1aregulatesthecellcyclethroughATPandROSinCH1cells.JZUSB,17(2):136-146.
8.WeiXu,ZexiChen,NaeemAhmed,BingHan,QinghuaCui*andAizhongLiu*.2016.Genome-WideIdentification,EvolutionaryAnalysis,andStressResponsesoftheGRASGeneFamilyinCastorBeans.Int.J.Mol.Sci.17,1004;
9.W.Wang,Y.Ye,J.Li,X.Li,X.Zhou,D.Tan,Y.Jin,E.Wu,Qinghua.CuiandM.Wu.2014.LynRegulatesCytotoxicityinRespiratoryEpithelialCellsChallengedbyCigaretteSmokeExtracts.Curr.Mol.Med.14,1-10
10.WeiXu#,QinghuaCui#,FeiLi,AizhongLiu*.2013.Transcriptome-wideidentificationandcharacterizationofMicroRNAsfromcastorbean(RicinuscommunisL.).PLOSONE,8(7):e69995.
11.QinghuaCui,MaydaValentin,YelenaJanumyan,ElizabethYang.2009.Bax-/-bak-/-cellsexhibitp27Thr198phosphorylationandautophagy.Autophagy5(2):263-264.
12.YelenaJanumyan#,QinghuaCui#,LingYan,CourtneyG.Sansam,ElizabethYang.2008.GofunctionofBCL2andBCL-xLrequiresBAX,BAK,andp27phosphorylation,revealinganovelroleofBAXandBAKinquiescenceregulation.JBC,283:34108;34120.
13.LingYan,VivianaA.Lavin,LetaR.Moser,QinghuaCui,CindyKanies,andElizabethYang.2008.PP2ARegulatesthePro-apoptoticActivityofFOXO1.JBC283:7411;7420.
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