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个人简介

工作经历 2017.12-至今,云南大学,研究员 2006.11-2017.11,云南大学,人才引进,副研究员 2005.4-2005.10,日本国立鹿儿岛大学,博士后 1999.7-2001.3,云南农业大学任助教 学习经历 2001.4-2005.3,日本国立山口大学获博士学位(硕博连读) 1994.9-1999.7,中央民族大学获学士学位 2017.1,入选昆明市中青年学术和技术带头人 2015.11,入选云南省中青年学术和技术带头人后备人才 2010.7,遴选为云南大学硕士生导师 2018.5,入选云南大学“青年英才培育”项目

研究领域

疾病分子机制研究 疾病相关生物标志物的检测

近期论文

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ZhaoH#,LiuF#,LuYX,JinL,TangS,ZhangYP*,LiCP*.UltrasensitiveelectrochemicaldetectionofalternativecleavageandpolyadenylationofCCND2geneatsinglecelllevel.2019.Sensors&Actuators:B.Chemical.2019.285:553-561. TanS,HanR,WuSL,LiangH,ZhaoYT,ZhaoH*,LiCP*.Anovelfluorescentsensingplatformforinsulindetectionbasedoncompetitiverecognitionofcationicpillar[6]arene.Talanta.2019.1:130-137. ZhouZY#,HuY#,LiA#,LiYJ#,ZhaoH#,WangSQ,OteckoNO,ZhangD,WangJH,LiuY,IrwinDM,QinY,ZhangYP.Genomewideanalysesuncoverallele-specificRNAeditinginhumanandmouse.NucleicAcidsRes.2018,46(17):8888-8897. ZhaoH#,LiuF#,WuSL,YangL,ZhangYP*,LiCP*.UltrasensitiveelectrochemicaldetectionofDicer13’UTRforthefastanalysisofalternativecleavageandpolyadenylation.Nanoscale.2017.9:4272-4282. ZhaoH,MaTF#,LinJ#,LiuLL,SunWJ,GuoLX,WangSQ,OteckoNewtonO,ZhangYP*.IdentificationofvalidreferencegenesformRNAandmicroRNAnormalisationinprostatecancercelllines.ScientificReports.2018.8:1949. ZhaoH#,WangSQ#,GuoLX#,DuYL,LiuLL,MaTF,OteckoNO,LiCP*,ZhangYP*.Fixeddifferencesinthe3’UTRofbuffaloPRNPgeneprovidebindingsitesformiRNAspost-transcriptionalregulation.Oncotarget.2017.8(28):46006-46019. ZhaoH#,YangL#,LiYC,RanX,YeHZ,ZhaoGF,ZhangYQ,LiCP*.Acomparisonstudyofmacrocyclichostsfunctionalizedreducedgrapheneoxideforelectrochemicalrecognitionoftadalafil.BiosensBioelectron.2017.89:361-369. YeYQ#,ZhaoH#,ZhouHJ#,RenXD#,LiuLL#,OteckoNO,WangZB,YangMM,ZengL,HuXT,YaoYG,ZhangYP*,WuDD*.TheRNAeditomeofMacacamulattaandfunctionalcharacterizationofRNAeditinginmitochondria.ScienceBulletin.2017.62:820–830. ZhaoH,WangSQ,QingLL,LiuLL,ZhangYP.ExpressionofBSE-associatedproteinsintheCNSandlymphoreticulartissuesofcattleandbuffalo.ScienceBulletin.2016.61(17):1377-1383. YangL,XieXG,CaiL,RanX,LiYC,YinTP,ZhaoH*,LiCP*.P-sulfonatedcalix[8]arenefunctionalizedgraphemeasa“turnon”fluorescentsensingplatformforaconitinedetermination.BiosensBioelectron.2016.82:146-154. YangL,RanX,CaiL,LiYC,ZhaoH*,LiCP*.Calix[8]arenefunctionalizedsingle-walledcarbonnanohornsfordual-signallingelectrochemicalsensingofaconitinebasedoncompetitivehost-guestrecognition.BiosensBioelectron.2016.83:347-352. YangL,ZhaoH#,LiYC,RanX,DengGG,ZhangYQ,YeHZ,ZhaoGF,LiCP.Indicatordisplacementassayforcholesterolelectrochemicalsensingusingacalix[6]arenefunctionalizedgrapheme-modifiedelectrode.Analyst.2015.141:270-278. ZhaoH#,DuYL#,ChenSM,QingLL,WangXY,HuangJF,WuDD,ZhangYP*.Theprionproteingenepolymorphismsassociatedwithbovinespongiformencephalopathysusceptibilitydiffersignificantlybetweencattleandbuffalo.InfectGenetEvol.2015.36:531-538. YangL,ZhaoH#,LiYC,RanX,DengGG,XieXG,LiCP*.Fluorescentdetectionoftadalafilbasedoncompetitivehost-guestinteractionusingp-sulfonatedcalix[6]arenefunctionalizedgrapheme.ACSApplMaterInterfaces.2015.7:26557-26565. YangL#,ZhaoH#,DengGG,RanX,LiYC,LiCP*Immunosensorforprostate-specificantigenusingAu/Pd@flower-likeSnO2asplatformandAu@mesoporouscarbonassignalamplification.RSCAdv.2015.5:74046-74053. YangL#,ZhaoH#,FanSM,ZhaoGF,RanX,LiCP.*Electrochemicaldetectionofcholesterolbasedoncompetitivehost–guestrecognitionusingaβ-cyclodextrin/poly(N-acetylaniline)/graphene-modifiedelectrode.RSCAdv.2015.5:64146-64155. LiuLL#,ZhaoH#,MaTF,GeF,ChenCS,ZhangYP*.IdentificationofvalidreferencegenesforthenormalizationofRT-qPCRexpressionstudiesinhumanbreastcancercelllinestreatedwithandwithouttransienttransfection.PLoSONE.2015.10(1):e0117058. YangL#,ZhaoH#,LiCP*,FanS,LiB.Dualβ-cyclodextrinfunctionalizedAu@SiCnanohybridsfortheelectrochemicaldeterminationoftadalafilinthepresenceofacetonitrile.BiosensBioelectron.2015.64:126-130. YangL#,ZhaoH#,FanS,DengS,LvQ,LinJ,LiCP*Label-freeelectrochemicalimmunosensorbasedongold-siliconcarbidenanocompositesforsensitivedetectionofhumanchorionicgonadotrophin.BiosensBioelectron.2014.57:199-206. YinCY,YangL,ZhaoH*,LiCP*.Improvementofantioxidantactivityofeggwhiteproteinbyphosphorylationandconjugationofepigallocatechingallate.FoodResInt.2014.64:855-863. LiCP*,HeZ,WangX,YangL,YinC,ZhangN,LinJ,ZhaoH*.Selenizationofovalbuminbydry-heatinginthepresenceofselenite:effectonproteinstructureandantioxidantactivity.FoodChem.2014.148:209-217. WangSQ,ZhaoH*,ZhangYP.AdvancesinresearchonShadoo,Shadowofprionprotein.ChineseSciBull.2014.59(9):821–827. ZhaoJP#,ZhaoH#,WangX,HuangR,EnomotoH,HeZ,LiCP*.Characteristicsandenhancedantioxidantactivityofeggwhiteproteinselenizedbydry-heatinginthepresenceofselenite.JAgricFoodChem.2013.61:3131-3139. HuangR,LiCP,ChenD,ZhaoG,ChengW,ZhangY,ZhaoH*.Preparationofphosphorylatedstarchbydry-heatinginthepresenceofpyrophosphateanditscalcium-phosphatesolubilizingability.JFoodSci&Technol.2013.50:561-566. ZhaoH#,LiuLL#,DuSH,WangSQ,ZhangYP*.ComparativeanalysisoftheShadoogenebetweencattleandbuffalorevealssignificantdifferences.PLoSOne.2012.7(10):e46601. ZhaoH,MitsuikiS*,TakasugiM,SakaiM,GotoM,KanouchiH,OkaT.Decompositionofinsolubleandhard-to-degradeanimalproteinbyenzymeE77anditspotentialapplications.ApplBiochemBiotechnol.2012.166(7):1758-1768. ZhaoH,WangXY,ZouW,ZhangYP*.Prionproteingene(PRNP)polymorphismsinnativeChinesecattle.Genome.2010.53:138-145. LiCP,EnomotoH,HayashiY,ZhaoH*,AokiT.Recentadvancesinphosphorylationoffoodprotein:Areview.LWT-FoodSci.&Technol.2010.43:1295-1300. WangXY,LiNZ,YuL,ZhaoH,ZhangYP*.Duplicationandfunctionaldiversificationofpancreaticribonuclease(RNASE1)Gene.ChineseSciBull.2010.55:2-6. ZhaoH,WangXY,ZhangYP*.Theindelpolymorphismsofprionproteingene(PRNP)inChineseyak.AnimGenet.2009.40:575-576. QingLL,ZhaoH*,LiuLL.Progressonlowsusceptibilitymechanismsoftransmissiblespongiformencephalopathies.ZoologicalResearch.2014.35(5):436-445.2 MitsuikiS,ZhaoH,MatsumotoD,SakaiM,MoriyamaY,FurukawaK,KanouchiH,OkaT.DegradationofPrPScbykeratinolyticproteasefromNocardiopsissp.TOA-1.BiosciBiotechnolBiochem.2006.70:1246-1248. ZhaoH,DoiH,KanouchiH,MatsuuraY,MohriS,NonomuraY,OkaT.AlkalineserineproteaseproducedbyStreptomycesspdegradesPrPSc.BiochemBiophysResComm.2004.321:45-50. ZhaoH,MinamiguchiK,DoiH,KinoshitaN,KanouchiH,OkaT.RecombinantalkalineserineproteaseIIdegradesPrPSc.InVitroCellDev-An.2004.40:293-296.

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