个人简介

学习经历 2009.9-2013本科西南大学动物医学 2013.9-2015硕士研究生中国农业大学基础兽医学 2015.7-2018博士研究生中国农业大学基础兽医学 工作简历 2018.7至今扬州大学兽医学院校特聘教授

研究领域

研究方向为兽医药理学与毒理学，主要包括:1)新型抗生素及抗生素增效剂开发；2)新型抗感 染策略的硏究；3)细菌新型耐药机制的硏究。

科研情况 重点研发计划,2018YFA0903400，高版本模式微生物底盘细胞,201907-2024/06，任务负责人 江苏省青年基金项目，B2019089，二甲双那逆转细菌多西环素耐药性的分子机制研究 江苏省科协青年科技人才托举工程,2019/08-2021/09，主持 扬州大学高层次人才科研启动费,137000463，新型非核糖体肽类抗生素的筛选及机制研究 2018/7-2022/7，主持

近期论文

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1YuanLiu,ShuangyangDing,RichardDietrich,ErwinMartlbauer,KuiZhu*.Abiosurfactant-inspiredheptapeptidewithimprovedspecificitytokillMRSAAngewandteChemieInternationalEdition,2017,56,1486-1490.(Frontispiece)(HighlightedasofoutstandinginterestbyCurrentOpinioninMicrobiology,2017,37,95-102.) 2YuanLiu,ShuangyangDing,JianzhongShen,KuiZhu*.Nonribosonalantibacterialpeptidesthattargetmultidrug-resistantbacteria.NaturalProductReports,2019,36,573-592.(Cover 3YuanLiu,RuichaoLi,xiaXiao,ZhiqiangWang*.Bacterialmetabolism-inspiredmoleculestomodulateantibioticefficacy.JournalofAntimicrobialChemotherapy,2019,74,3409-3417 4YuanLiu,YuqianJia,KangniYang,RuichaoLi,xiaxiao,zhiqiangwang".Antagonizingvancomycinresistanceinenterococcusbysurfacelocalizedantimicrobialdisplay-derivedpeptides.ACSInfectiousDiseases,2019.DOI:10.1021/acsinfecdis.9b00164.(SpecialIssue"InfectiousDiseaseResearchinChina 5YuanLiu,KangniYang,YuqianJia,ZhiqiangWang*.RepurposingpeptidomimeticaspotentialinhibitorofNewDelhiMetallo-B-lactamasesinGram-negativebacteria.ACSInfectiousDiseases,2019,5,2061-2066 6YuanLiu,MeirongSong,ShuangyangDing,KuiZhu*.DiscoveryoflowcationicpeptidestotargetMRSAinvivo.ACSInfectiousDiseases,2019,5,123-130 7YuanLiu,RuichaoLi,XiaXiao,ZhiqiangWang*.Antibioticadjuvants:analternativeapproachtoovercomemulti-drugresistantGram-negativebacteria.CriticalReviewsinMicrobio1ogy,2019,45,301-314. 8YuanLiu,RuichaoLi,xiaxiao,ZhiqiangWang*.Moleculesthatinhibitbacterialresistanceenzymes.Molecules,2019,24,43 9.TianqiMin,MinLiu,HaijieZhang,YuanLiu*,ZhiqiangWang.Molecularandpharmacologicalcharacterizationofpoultry(Gallusgallus,Anasplatyrhynchos,Ansercygnoidesdomesticus)andpig(Susscrofadomestica)melanocortin-5receptorsandtheirmutants.GeneralandComparativeEndocrinology,2019,283,113233 10YuanLiu#,KuiZhu,JianfenWang,XiaoyongHuang,GuanlinWang,CongyingLi,JiCao*,ShuangyangDing*.Simultaneousdetectionandcomparativepharmacokineticsofamoxicillin,clavulanicacidandprednisoloneincowsmilkbyUPLC-MS/S.JournalofChromatographyB,2016,1008,74-80. 11YuanLiu,JianyeLiu,xiaoweiLi,KmriaZhao,Pengchmzhang,ShuangyangDing,Determinationofmeropenemandertapeneminlagoonwater,beddingsoil,andsilagebyhigh-performanceliquidchromatography-tandenmassspectrometry.2017,50,1387-1396 12.ShupengYang*,YuanLiu,FeifeiSun,JinzhenZhang,YueJin,YanshenLi,Jinhuiou*,YiLi*,KuiZhu*.Gelsedine-typealkaloids:Discoveryofnaturalneurotoxinspresentedintoxichoney.JournalofHazardousMaterials,2020,381,120999 13.YifangCui,YuanLiu,XiaoyeLiu,XiXia,ShuangyangDing*,KuiZhu*.EvaluationofthetoxicityandtoxicokineticsofcereulidefromanemeticBacilluscereusstrainofmilkorigin.Toxins,2016,8,156.