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1.Liu,W,Jiang,Y,Sun,J,Geng,S,Pan,Z,Prinz,R.A,Wang,C,Sun,J.Jiao,X,Xu,X.Xu,X*.(2018)ActivationofTGF-beta-activatedkinase1(TAK1)restrictsSalmonellaTyphimuriumgrowthbyinducingAMPKactivationandautophagy,CellDeathDisease,Inpress
2.Sun,J,Mu,Y,Jiang,Y,Song,R,Yi,J,Zhou,J,Sun,J,Jiao,x,Prinz,RA,Li,Y,Xu,x*.(2018)Inhibitionofp70S6kinaseactivitybyA771726inducesautophagyandenhancesthedegradationofsuperoxidedismutase1(soD1)proteinaggregates,CellDeathDisease,DOIVol.9,DOI101038/s41419-018-0441-0
3.ChenJ,SunJ,DoscasME:YeJ,WilliamsonA,LiY,LiY,PrinRA,XuX*.(2018)Controlofhyperglycemiainmalemicebyleflunomide:mechanismsofaction.J.Endocrinol.237(1):43-58.
4.Xu,X*,Lu,Y,Li,Y,Prinz,R.(2017)SonichedgehogsignalinginthyroidcancerFrontiersinEndocrinol.DOI103389/fend2017.00284
5.Xu,x*,Sun,J,Song,R,Doscas,M.E.,Williamson,A.J.,Zhou,J,Sun,J.Jiao,X,Liu,X,Li,Y.(2017)Inhibitionofp70S6kinase(S6K1)activitybyA771726,theactivemetaboliteofleflunomide,inducesautophagythroughTAK1-mediatedAMPKandJNKactivation.OncotargetPublishedonlinedoi:10.18632/oncotarget.16737
6.Xux*,RaoG,andLiY.(2016).Xanthineoxidoreductaseisrequiredforgenotoxicligandexpressionandgemcitabine-mediatedantitumoractivity.Oncotarget.7:59220-59235
7.WilliamsonAT,DoscasME,YeJ,HeidenKB,XingM,LiY,PrinzRA,andXuX*(2016)ThesonichedgehogsignalingpathwaystimulatesanaplasticthyroidcancercellmotilityandinvasivenessbyactivatingAktandc-Met.Oncotarget.7:10472-85
8.Doscas,M.E,willianson,A,Usha,L,Bogachkov,Y,Rao,G.S.,Xiao,F,Wang,W,Ruby,C,Kaufman,H,Zhou,Z,Williams,J.W,Li,Y,Xu,X*.(2014)Inhibitionofp70s6kinase(S6K1)activitybyA771726anditseffectoncellproliferationandcellcycleprogress.Neoplasia16(10):824-34.
9.Heiden,K.B,Williamson,A.J,Doscas,M.E,Ye,J,Wang,Y,Prinz,R.A,Xu,x*.(2014)Thesonichedgehogsignalingpathwaymaintainsanaplasticthyroidcancerstemcellself-renewalbyinducingSnailexpression.J.ClinicalEndo.Metab.99(11):E2178-87
10.Xu,X*,Ding,HG,Rao,G.Arora,S,Gattuso,P,Solorzano,C,Prinz,RA.(2012)WidespreadexpressiontheSonicHedgehogpathwaymoleculesinthyroidtumorsanditsroleincellproliferation.Endocrine-RelatedCancer.19:167-179
11.Rao,G,Ding,HG,Huang,W,Maxhimer,JB,Lewis,EJ,Reddy,v.,Prinz,RA.,xu,X*,(2011)Highglucoseinducesheparanase.proteoglycandegradationintheendothelialcellsbyreactiveoxygenspeciesproduction:Apotentialroleindiabetes-relatedatherosclerosis.Diabetologia,54:1527-1538
12.WiinhovenT,vandenHoven,Ding,H,Kuppervelt,T.H.,vandenVlog,J,Berden,T,Lewis,E.J.,Schwartz,M,andXu,x*(2008)Heparanaseinducesadifferentiallossofheparansulfatedomainsinovertdiabeticnephropathy.Diabetologia51:372-382
13.Xu,X*,Rao,G,Quiros,R.Q.,Kim,A.W.,Brunn,G.J.,Platt,J.L.Gattuso,PPrinz,RA.(2007)Invivoandinvitrodegradationofheparansulfate(HS)proteoglycansbyheparanase-1(HPR1)inpancreaticadenocarcinomas:LossofcellsurfaceHSsuppressesFGF2-mediatedcellsignalingandproliferation.J.Biol.Chem282:2363-2373
14.Xu,x*,Rao,R,Gaffud,MJ,Ding,HG,Maki,G,Klingemann,H.G,Groh,V,Spies,T,Caillat-Zucman,S,Gattuso,P,Plate,J.Prinz,R.A.(2006)clinicopathologicsignificanceofmajorhistocompatibilitycomplexclassI-relatedchainAandB(MICA/B)expressioninthyroidcancer.J.clin.Endo.Metab.91:2704-2712
15.Maxhimer,J.B,Somenek,M,Rao,G,CatherineE.Pesce,C.E,Baldwin,D.Jr,Gattuso,P,Schwartz,M.M,Lewis,E.J,Prinz,R.AandXu,X*.(2005)Heparanase-1geneexpressionandregulationbyhighglucoseinrenalepithelialcells:apotentialroleinthepathogenesisofproteinuriaindiabeticpatients.Diabetes54:2172-2178
16.Xu,X'Quiros,R.L,Shen,I,Gattuso,P,Ain,K.B.,Prinz,R.A.(2003)HighprevalenceofBRAFgenemutationinpapillarythyroidcarcinomasandthyroidtumorcelllines.CancerRes.63:4561-4561
17.Xu,x*,Quiros,R.M,JustinB.Maxhimer,J.B,Jiang,J.Marcinek,R,AinK.B,Platt,J.L,Shen,J
Gattuso,P.Prinz,R.A.(2003)Inversecorrelationbetweenheparansulfatedepositionandheparanase-1geneexpressioninthyroidpapillarycarcinomas:apotentialroleintumormetastasis.Clin.CancerRes9:59686979
18.Jiang,P,Kumar,A,Parrillo,J.E,Dempsey,L.A,Platt,J.L.,Prinz,R.A,andXu,x*.(2002)Cloningandcharacterizationofthehumanheparanase1(HPR1)genepromoter:RoleofGA-bindingprotein(GABP)andSplinregulatingHPR1basalpromoteractivity.JBiolChem,277:8989-8998
19.Li,X.,A.S.-F.Chong,J.Wu,K.Roebock,A.Kunar,R.Kimberbly,U.R.Rapp,Jw.Williams,andX,Xu*(1999)TranscriptionalregulationofFasgeneexpressionbyGA-bindingprotein(GABP)andAP-1transcriptionfactorsinTcellantigenreceptor/CD3-activatedTcells.].Biol.Chem.274:35203-35210
20.u,X*,X-Y,Fu,J.Plate,andA.S.-F.Chong.1998)IFN-inducescellgrowthinh1bitionbyFas-mediatedapoptosis:RequirementofSTATIproteinforup-regulationofFasandFasL.CancerRes.58:2832-2837Xu,x*,williams,J.wShen,J,Gong,H,Yin,D,Blinder,L.Elder,R.T,Sankary,H,Finnegan,A.andChong,A.S-F.(1998)Invitroandinvivomechanismsofactionoftheanti-proliferativeandimmunosuppressiveagent,brequinarsodium.Immuno160:846-853.
21.Xu,X*,H.Gong,J.Shen,A.Finnegan,J.W.Williams,andA.S.-F.Chong.(1997)InvivomechanismbywhichleflunomidecontrolslymphoproliferativeandautoimmunediseaseinMRL-lpr/lprmice.J.Immunol.159:167-174
22.Xu,X.andA.S-F.Chong(1995)Cross-linkingofCD45onNKcellsstimulatesp56lck-mediatedtyrosinephosphorylationandIFN-production.Immuno155:5241-5248