个人简介

学习经历 1997.9-2001.7本科四川畜牧兽医学院畜牧兽医 2001.9-2004.8硕土研究生浙江大学预防兽医学 2004.9-2007.12博士研究生浙江大学微生物学 工作简历 2018.3-至今扬州大学兽医学院特聘教授 2011.1-2018.6美国西北大学医字院副研究员(ResearchAssociate) 2008.3-2010.12美国科罗拉多州立大学博士后

研究领域

感染与免疫:1.畜禽传染病、人兽共患病诱导的r细胞免疫特征与应用。 2.抗结核T细胞免疫保护机制与记忆反应

1，“细胞免疫在畜禽传染病、人兽共患病中的作用”,2018-2021，“江苏特聘教授”人才专项，主持 2，“畜禽细胞免疫研究平台的建立”,2018-2021，扬州大学高层次人才启动经费，主持 3，“猪圆环病毒免疫的分子识别机制”,2008-2010，国家自然科学基金·青年基金:3070025。主持 4,TheroleofMHcclassIbinTcelldevelopmentandinfectiousdisease:4RO1AI040310- 19.2012-2017。美国M金，参与。 5,Theroleofgroup1CD1-restrictedTcellsininfectiousdisease:2RO1AI057460-12A1 2017-2021。美国MH基金，参与。 6,Developmentoflipid-basednanoparticlevaccinesagainstMycobacterium Tuberculosis:1R21A13105-02.2017-2018。美国基金，参与

近期论文

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1.ShangS,KatsD,CaoL,VellutoD,HeY,ScottE,WangCR.InductionofMycobacteriumtuberculosislipid-specificTcellresponsebypulmonarydeliveryofmycolicacid-loadedmicellenanoparticle.2018.FrontiersinImmunology(Submitted) 2.BianY,ShangS,SiddiquiS,ZhaoJ,JoostenS,OttenhoffT,CantorH,WangCR.MHCIbMoleculeQa-1PresentsMycobacteriumtuberculosisPeptideAntigenstoCD8+TCellsandContributestoProtectionAgainstInfection,PLOSPathogens,2017,13(5)e1006384. 3.ShangS,SiddiquiS,ZhaoJ,BianY,andWangCR.NonclassicalICIb-restrictedCD8+Tcellsrecognizemycobacteriumtuberculosis-derivedproteinantigensandcontributetoprotectionagainstinfection.PLOSPathogens,2016,12(6):e1005688 4.BaiX,ShangS#,Henao-TamayoM,BasarabaRT,OvrutskyAR,MatsudaJL,Takedak,Chanm,DakhamaA,KinneyWH,etal.HumanIL-32expressionprotectsmiceagainstahyper-virulentstrainofMycobacteriumtuberculosis.ProcNatlAcadSciUSA.2015112(16):5111-6.(eco-firstauthor 5.ZhaoJ,SiddiquiS,ShangS,BianY,BagchiS,HeY,andWangCR.Mycolicacid-specificTCellsprotectagainstmycobacteriumtuberculosisinfectioninahumanizedtransgenicmousemodel.Elife.2015,4:e08525 6.ShangS,ShanleyCA,Carawayl,OrmeEA,Henao-TamayoM,Hascall-DoveL,AckartDOrmeI,OrdwayDJ,BasarabaRI.DrugtreatmentcombinedwithBCGvaccinationreducesdiseasereactivationinguineapigsinfectedwithMycobacteriumtuberculosis.Vaccines.2012,30(9):1572-82 7.ShangS,OrdwayD,Henao-TamayoM,BaiX,OberleyDeeganR,ShanleyC,OrmeIM,CaseS,MinorM,AckartD,Hascall-DoveL,OwrutskyAR,KandasamyP,VoelkerDR,LambertcFreedBM,IsemanMD,BasarabaR,ChanED.Cigarettesmokeincreasessusceptibilitytotuberculosis--evidencefrominvivoandinvitromodels.JInfectDis.2011,203(9):1240-8 8.ShangS,ShanleyCA,CarawayML,OrmeEA,Henao-TamayoM,Hascall-DoveL,AckartDLenaertsA,BasarabaR],OrmeIM,OrdwayD].ActivitiesofTMC207,rifampin,andpyrazinamideagainstmycobacteriumtuberculosisinfectioninguineapigs.AntinicrobAgentsChemother.2011,55(1):124-316 10.ShangS,HartonM,TamayolB,ShanleyC,PalanisamyGS,CarawayM,ChanED,Basd'mabaR,OrmeIM,OrdwayD].IncreasedFoxp3expressioninguineapigsinfectedwithw-BeijingstrainsofM.tuberculosis.Tuberculosis(Edinb.2011,91(5):378-85 11.Rennal,SchaffnerC,BrowmK,ShangS,TamayoMH,HegyiK,GrimseyN],CusensDouterS,CooperJ,BowdenAR,NewtonSIl,KampmannB,HelnJ,JonesA,HaworthsarabaRT,DeGrooteMA,OrdwayDI,RubinszteinDC,FlotoRA.Azithromycinblocksaurtophagyandmaypredisposecysticfibrosispatientstomycobacterialinfection.JClinInvest.2011,121(9):3554-63 12.ShangSB,JinYL,JiangXT,ZhouJY,Zhang3,xingG,HeJL,YanY.Finemappingofantigenicepitopesoncapsidproteinsofporcinecircovirus,andantigenicphenotypeof 13.ShangSB,LiYF,GuoJQ,WangZT,ChenQX,ShenHG,ZhouJY.Developmentandvalidartionofarecombinantcapsidproteir-basedELISAfordetectionofantibodytoporcinecircovirustype2.ResVetSci.2008,84(1):150-7 14.ZhouJY*,ShangSB,GongH,ChenQx,WuJx,ShenHG,ChenTF,GuoJQ.Invitroexpression,monoclonalantibodyandbioactivityforcapsidproteinofporcinecircovirustypeIIwithoutnuclearlocalizationsignal.JBiotechnol.2005,118(2):201-11

学术兼职

2014—现在免疫学会会员 2013-现在VaccinejounalofInfectiousDiseases，fournalofGeneraly01g等期刊特约审稿人