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个人简介

学习经历 1960-1965本科原苏北农学院兽医硕士研究生 进修情况 1980-1982美国密西根州立大学兽医(生物技术) 1989.02-1989.10美国密西根州拉立大学病毒分子生物学 1992-1994美国农业部AoL实验室病毒分子生物学 1999-2000美国国立卫生研究院肿瘤分子生物学 工作简历 1965-1980原苏北农学院江苏农学院助教(助教、临床兽医) 1980-1986江苏农学院讲师(讲师) 1986-至今江苏农学院扬州大学教授(教授)

研究领域

主要从事动物疫病防控技术研究。在动物重要传染病的流行病学与致病机理方面开展了研究工作;先后硏制岀用于禽流慼、鸡传染性法氏蠹病、新城疫等疫病预防的7种新型疫苗,全国范围内得到了推广应用

近期论文

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[1]HaoX,HuJ,WangJ,XuJ,ChengH,XuY,LiQ,HeD,LiuX,WangX,GuM,HuSXux,LiuH,ChenS,PengD.ReassortantH5N1avianinfluenzavirusescontainingPAorNPgenefromanH9N2virussignificantlyincreasethepathogenicityinmice.VetMicrobio1,2016,192,95-101 [2]XuH,SongQ,ZhuJ,LiuJ,ChengX,HuS,LiuX.AsingleR36Qmutationinthematrixproteinofpigeonparamyxovirustype1reducesvirusreplicationandsheddinginpigeons.ArchVirol,2016,161:1949-55 [3]LiuQ,HuangJ,ChenY,ChenH,LiQ,HeL,HaoX,LiuJ,GuM,HuJ,WangX,HuS,LiuX.VirulencedeterminantsinthePB2geneofamouse-adaptedH9N2virus.Jviro1,2015,89:877-82 [4]LiQ,WangX,SunZ,HuI,GaoZ,HaoX,LiJ,LiuH,GuM,XuX,LiuX.AdaptivemutationsinPB2genecontributetothehighvirulenceofanaturalreassortantH5N2avianinfluenzavirusinmice.VirusRes,2015,210:255-63 [5]LiQ,Wangx,GaoZ,SunZ,CuiZ,DuanZ,LiJ,GuM,HuJ,LiuX.NovelreassortantH5N5virusesbindtoahuman-typereceptorasafactorinpandemicrisk.VetMicrobiol,2015,175:356-61. [6]HuZ,HuJ,HuS,SongQ,DingP,ZhuJ,LiuX,WangX.HighlevelsofvirusreplicationandanintenseinflammatoryresponsecontributetotheseverepathologyinlymphoidtissuescausedbyNewcastlediseasevirusgenotypeVIId.ArchVirol2015,160:639-48 [7]HuJ,MoY,WangX,GuM,HuZ,ZhongL,WuQ,HaoX,HuS,LiuW,LiuH,LiuxPA-xdecreasesthepathogenicityofhighlypathogenicH5N1influenzaAvirusinavianspeciesbyinhibitingvirusreplicationandhostresponse.JVirol,2015,89:4126-42. [8]ZhongL,Zhao4,ZhaoK,WangX,ZhaoG,LiQ,GuM,PengD,LiuX.TheantigenicdriftmolecularbasisoftheH5N1influenzavirusesinanovelbranchofclade2.3.4.VetMicrobiol,2014,171:23-30. [9]ZhongL,WangX,LiQ,LiuD,ChenH,ZhaoM,GuX,HeL,LiuX.MolecularmechanismoftheairbornetransmissibilityofH9N2avianinfluenzaAvirusesinchickens.Jviro1,2014,88:9568-78 [10]LiQ,WangX,ZhongL,SunZ,GaoZ,CuiZ,ZhuJ,GuM,LiuX.AdaptationofanaturalreassortantH5N2avianinfluenzavirusinmice.VetMicrobiol,2014,172:568-74 [11]LiQ,WangX,GuM,ZhuJ,HaoX,GaoZ,SunZ,HuJ,HuS,LiuX.NovelH5clade2.3.4.6viruseswithbothalpha-2,3andalpha-2,6receptorbindingpropertiesmayposeapandemicthreat.VetRes,2014,45:127 [12]GuM,ChenH,LiQ,HuangJ,ZhaoM,GuX,JiangK,WangX,PengD,LiuX.EnzooticgenotypeSofH9N2avianinfluenzavirusesdonatesinternalgenestoemergingzoonoticinfluenzavirusesinChina.VetMicrobiol,2014,174:309-15 [13]DuanZ,LiJ,ZhuJ,ChenJ,XuH,WangY,LiuH,HuS,LiuX.Asingleaminoacidmutation,R42A,intheNewcastlediseasevirusmatrixproteinabrogatesitsnuclearlocalizationandattenuatesviralreplicationandpathogenicity.JGenVirol,2014,95:1067-73. [14]DuanZ,ChenJ,XuH,ZhuJ,LiQ,HeL,LiuH,HuS,LiuX.ThenucleolarphosphoproteinB23targetsNewcastlediseasevirusmatrixproteintothenucleoliandfacilitatesviralreplication.Virology,2014,452-453:212-22. [15]ZhaoK,GuM,ZhongL,DuanZ,ZhangY,ZhuY,ZhaoG,ZhaoM,ChenZ,HuS,LiuW,LiuX.CharacterizationofthreeH5N5andoneH5N8highlypathogenicavianinfluenzavirusesinChina.VetMicrobiol,2013,163:351-7. [16]HuJ,HuZ,SongQ,GuM,LiuX,WangX,HuS,ChenC,LiuH,LiuW,ChenS,PengD.ThePA-gene-mediatedlethaldisseminationandexcessiveinnateimmuneresponsecontributetothehighvirulenceofH5N1avianinfluenzavirusinmice.JVirol2013,87:2660-72 [17]HuJ,HuZ,MoY,WuQ,CuiZ,DuanZ,HuangJ,ChenH,ChenY,GuM,WangX,HuS,LiuH,LiuW,Liu,X.ThePAandHAgene-mediatedhighviralloadandintenseinnateimmuneresponseinthebraincontributetothehighpathogenicityofH5N1avianinfluenzavirusinmallardducks,JVirol,2013,87:11065775. [18]GuM,ZhaoG,ZhaoK,ZhongL,HuangJ,WanH,Wangx,Liuw,LiuH,PengD,LiuX.NovelVariantsofClade2.3.4HighlyPathogenicAvianInfluenzaA(H5N1)Viruses,China.EmergInfectDis,2013,19:2021-4[19]ZhaoG,GuX,LuX,PanJ,DuanZ,ZhaoK,GuM,LiuQ,HeL,ChenI,GeS,WangY,ChenS,WangX,PengD,WanH,LiuX.NovelreassortanthighlypathogenicH5N2avianinfluenzavirusesinpoultryinChina.PLoSOne,2012,7:e46183 [20]SunQ,ZhaoL,SongQ,WangZ,QiuX,ZhangW,ZhaoM,ZhaoG,LiuW,LiuH,LiY,LiuX.Hybrid-andcomplex-typeN-glycansarenotessentialforNewcastlediseasevirusinfectionandfusionofhostcells.Glycobiology,2012,22:369-78

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