研究领域
主要从事纳米生物技术与纳米材料领域的研究,具有生物医学、药学及纳米材料学等多学科交叉背景,研究兴趣包括:(1)纳米疫苗与纳米免疫佐剂5(2)基因工程化噬菌体与噬菌体纳米材料;(3)新型高分子生物材料用于基因治疗。
科研情况
1.高效蛋白/DNA共逢送杂化纳米疫苗的构建及其抗流感病毒作用研究,2018-2022,扬州大学拔
尖人才(青年百人)科研经费,主持。
2.基于氧化作用的聚合药物研究及其在siRNA递送中的应用,2017-2018,江苏省研究生科研创新
计划项目,主持。
此外,参与国家自然科学基金6项,江苏省自然科学基金1项。
近期论文
查看导师新发文章
(温馨提示:请注意重名现象,建议点开原文通过作者单位确认)
1.Chen,G.:Wang,Y.:Wu,P.:Zhou,Y.:Yu,F.:Zhu,C.:Li,Z.:Hang,Y.:Wang,K.;
Li,J.:Sun,M.*:Oupicky,D.*,ReversiblyStabilizedPolycationNanoparticlesfor
CombinationTreatmentofEarly—andLate-StageMetastaticBreastCancer.ACSNano
2018,12(7):6620-6636.(IF:13.709)
2.Chen,G.1:Wang,K.1;Hu,Q.:Ding,L.:Yu,F.:Zhou,Z.:Zhou,Y.:Li,J.:Sun,M.:
Oupicky,D.*,CombiningFluorinationandBioreducibilityforImprovedsiRNAPolyplex
Delivery.ACSAppliedMaterials&Interfaces2017,9⑸:4457-4466.(IF:8.097)
3.Chen,G.:Wang,K.;Wu,P.:Wang,Y.:Zhou,Z.:Yin,L.:Sun,M.:Oupicky,D.*,De-
velopmentofFluorinatedPolyplexNanoemulsionsforImprovedSmallInterferingRNADe-
liveryandCancerTherapy.NanoResearch2017,1-16.(IF:7.994)
4.Chen,G.:Wang,K.:Wang,Y.:Wu,P.:Sun,M.:Oupicky,D.*,FluorinationEnhances
SerumStabilityofBioreduciblePoly(amidoamine)PolyplexesandEnablesEfficientIn-
travenoussiRNADelivery.AdvancedHealthcareMaterials2017.(IF:5.609)
5.Chen,G.:Wang,K.:Ullaha,A.:Zhou,Y.:Ding,L.:Hu,Q.:Sun,M.:Oupicky,D.*:
Self-assembledFluoropolycationNanomicellesforImprovedsiRNASilencing.Journalof
ControlledRelease2017,259:e35-e36.(IF:7.877)
6.Chen,G.1;Wang,K.1,*;Zhou,Y.:Ding,L.:Ullah,A.:Hu,Q.:Sun,M.*;Oupicky,
D.*,OralNanostructuredLipidCarriersLoadedwithNear—InfraredDyeforImage-Guided
PhotothermalTherapy.ACSAppliedMaterials&Interfaces2016,8(38),25087-25095.
(IF:8.097)
7.Chen,G.1;Ding,L.1;Wu,P.:Zhou,Y.:Sun,M.;Wang,K.*;Oupicky,D.*,Polymeric
KicelleplexesforImprovedPhotothermalEndosomalEscapeandDeliveryofsiRNA.Poly-
mersforAdvancedTechnologies2018,1-8.(IF:2.137)
8.Chen,G.1:Yang,Y.1;Hu,C.:Cheng,X.:Xu,Y.:Cai,X.:Wang,M.:Yang,CS.*:Cao,
P.*,ProtectiveEffectsofHuangqinDecoctionagainstUlcerativeColitisandAssoci-
atedCancerinMice.Oncotarget2016,7(38):61643-61655.(IF:5.168)
9.Chen,G.:Yang,Y.:Liu,M.:Teng,Z.:Ye,J.:Xu,Y.:Cai,X.:Cheng,X.:Yang,J.;
Hu,C.:Wang,M.*:Cao,P.*,BanxiaXiexinDecoctionProtectsagainstDextranSulfate
Sodium-inducedChronicUlcerativeColitisinMice.JournalofEthnophaxmaco1ogy2015,
166:149-156.(IF:3.055)
10.Wang,K.1;Chen,G.1;Hu,Q.:Zhen,Y.:Li,H.:Chen,J.:Di,B.:Hu,Y.:Sun,M.*:
Oupicky,D.*,Self-assembledHemoglobinNanoparticlesforImprovedOralPhotosensi—
tizerDeliveryandOralPhotothermalTherapyinVivo.Nanomedicine2017,12(9),
1043-1055.(共一,IF:5.005)
11.Yang,Y.1:Chen,G.1;Yang,Q.1;Ye,J.:Cai,X.:Tsering,P.:Cheng,X.:Hu,C.:
Zhang,S.:Cao,P.*,GutMicrobiotaDrivestheAttenuationofDextranSulphate
Sodium-inducedColitisbyHuangqinDecoction.Oncotarget2017,8(30):48863-48874.(共
—,IF:5.168)
12.Wang,K.:Chen,G.:Ullaha,A.:Zhou,Y.:Ding,L.:Hu,Q.:Sun,M.;Oupicky,D.,
OralDeliveryofNIRDyeforPhotothermalTherapyBasedonSelf-assembledHemoglobin
Nanoparticles.JouxnalofControlledRelease2017,259:e73-e74.(IF:7.877)
13.Yang,Y.:Chen,G.:Cheng,X.:Teng,Z.:Cai,X.:Yang,J.:Sun,X.:Lu,W.:Wang,
X.:Yao,Y.:Hu,C.:Cao,P.*,Therapeuticpotentialofdigitoflavoneondiabeticne-
phropathy:nuclearfactorerythroid2-relatedfactor2-dependentanti-oxidantandanti-inflammatoryeffect.ScientificReports2015,24;5:12377.(IF:5.228)