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相辉,女,1978年生,教授,博士研究生导师。中国科学院青年创新促进会首批会员,云南省学术与技术带头人后备人才。2000年本科毕业于西北大学,2003年硕士毕业于中国科学院西双版纳热带植物园,2008年于中国科学院上海植物生理生态研究所获得博士学位,2010年从中国科学院昆明动物研究所博士后出站。2010.11-2016.3于中科院昆明动物研究所遗传资源与进化国家重点实验室王文研究员团队任副研究员,项目研究员。2016年3月作为“青年拔尖人才”引进申请单位全职工作。主要以家蚕等泌丝昆虫为研究对象,从表观遗传组学及基因组学、转录组学等多组学角度,结合基于基因组编辑的基因功能研究,探讨人工选择机制及泌丝动物茧丝进化机制,取得了一系列重要研究成果,引起广泛的国际关注。共发表SCI论文25篇,其中以第一或通讯(含共同通讯)作者在NatureBiotechnology,NatureEcologyandEvolution,MolecularBiologyandEvolution,Epigenomics等期刊发表论文16篇。主持973计划课题1项,国防科军委创新特区项目1项,国家自然科学基金面上项目2项,中国科学院“西部之光人才培养计划”重点项目1项(结题优秀)。获得省级自然科学二等奖一项(排名第二),省级优秀科技论文特等奖一项(排名第一)。担任昆虫学会基因组学专业委员会青年委员、广东省遗传学会青年委员会委员,为DNAresearch,Genetics,DiseaseModels&Mechanisms,BMCGenomics等期刊论文审稿。 个人主页:http://life.scnu.edu.cn/insectlab/researchTeam/jiaoshou/yanjiuyuan/ 团队SilkroadMiniclub:http://www.scholat.com/team/silkroad 受教育经历 1996/09-2000/07,西北大学,生物系,学士 2000/09-2003/07,中国科学院西双版纳热带植物园,硕士 2004/09-2008/03,中国科学院上海植物生理生态研究所,博士 研究工作经历 2003/07-2004/08,中国科学院上海植物生理生态研究所,研究助理 2008/04-2010/10,中国科学院昆明动物研究所,遗传资源与进化国家重点实验室马普进化基因组学研究组,博士后 2010/11-2012/03,中国科学院昆明动物研究所,遗传资源与进化国家重点实验室马普进化基因组学研究组,副研究员 2012/03-2016/03,中国科学院昆明动物研究所,遗传资源与进化国家重点实验室马普进化基因组学研究组,副研究员,硕士研究生导师 2016/04-现在,华南师范大学,教授

近期论文

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1.ZhuYN#,WangLZ#,LiCC,CuiY,WangM,LinYJ,ZhaoRP,WangW,XiangH*.2019.ArtificialSelectiononStorageProtein1PossiblyContributestoIncreaseofHatchabilityduringSilkwormDomestication.PlosGenetics.(Accepted) 2.XiangH#,LiuXJ#,LiMW#,ZhuYN,WangLZ,CuiY,etal.2018.Theevolutionaryroadfromwildmothtodomesticsilkworm.NatEcolEvol2(8):1268-1279. 3.CuiY#,ZhuYN#,LinYJ,ChenL,FengQL,WangW*,XiangH*.2018.Newinsightintothemechanismunderlyingthesilkglandbiologicalprocessbyknockingoutfibroinheavychaininthesilkworm.BMCGenomics19:215 4.LiCC,ZouC,CuiY,FuYH,FangCC,LiY,LiJX,WangW;XiangH*,LiCC*..2018.Genome-wideepigeneticlandscapeofpiglincRNAsandtheirevolutionduringporcinedomestication.Epigenomicsdoi:10.2217/epi-2017-0117. 5.RenY,ZhuY,WangG,XiangH*,WangBY*.2017.TranscriptomeofPterospermumkingtungenseprovidesimplicationsonthemechanismunderlyingitsrapidvegetativegrowthandlimestoneadaption.SciRep.7:3198 6.LiuL,WangJ,DuanS,ChenL,XiangH*,DongY*,WangW*.2016.Systematicevaluationofsericinproteinasasubstituteforfetalbovineserumincellculture.SciRep 6:31516. 7.LiCC,WangX,FuYH,LuanY,WenWang,XiangH*,LiCC*.2016.Molecularmicroevolutionandepigeneticpatternsofalongnon-codinggeneH19showitspotentialfunctioninpigdomesticationandbreeddivergence.BMCEvolutionaryBiology.(Co-correspondenceauthor)16:87 8.DongY,DaiFY,RenYD,LiuH,ChenL,YangPC,LiuYQ,LiX,WangW*,XiangH*.2015.Comparativetranscriptomeanalysesonsilkglandsofsixsilkmothsimplythegeneticbasisofsilkstructureandcoloration.BMCgenomics16:203 9.WuJ*,XiangH*,QiY,YangD,WangX,SunH,WangF,LiuB.2014.AdaptiveevolutionoftheSTRA6genesinmammalian.PloSOne9(9):e108388(Co-correspondenceauthor) 10.XiangH,LiX,DaiF,XuX,TanA,ChenL,ZhangG,DingY,LiQ,LianJ,WilldenA,GuoQ,XiaQ,WangJ,WangW.2013.Comparativemethylomicsbetweendomesticatedandwildsilkwormsimpliespossibleepigeneticinfluencesonsilkwormdomestication.BMCGenomics14:646 11.ZhanZB,DingY,ZhaoR,ZhangY,YuH,ZhouQ,YangS,XiangH*,WangW*.2012.RapidfunctionaldivergenceofanewlyevolvedpolyubiquitingeneinDrosophilaanditsroleinthetrade-offbetweenmalefecundityandlifespan,MolBiolEvol29:1407(Co-correspondenceauthor) 12.XiangH,ZhangJ,LongYH,XieL,LiuN,HuangYP,WangQ.2012.IntracolonialdifferencesbetweenworkerandsoldiercastesofCoptotermesformosanusingutbacterialCommunity.InsectScience9(1):86-95 13.XiangH,LiMW,GuoJH,JiangJH,HuangYP.2011.InfluenceofRNAiknockdownforE-complexgenesonthesilkwormprolegdevelopment.ArchInsectBiochemPhysiol76(1):1 14.XiangH,ZhuJD,ChenQ,DaiFY,LiX,etal.2010.Singlebase-resolutionmethylomeofthesilkwormrevealsasparseepigenomicmap.NatBiotechnol28:516 15.XiangH,LiM,YangF,GuoQ,ZhanS,LinH,MiaoX,HuangY.2008.FinemappingofEkp-1,alocusassociatedwiththesilkworm(Bombyxmori)prolegdevelopment.Heredity100(5):533 16.XiangH,WeiGF,JiaSH,HuangJH,MiaoXX,ZhouZH,ZhaoLP,HuangYP.2006.Microbialcommunitiesinthelarvalmidgutsoflaboratoryandfieldpopulationsofcottonbollworm(Helicoverpaarmigera).CanadianJournalofMicrobiology52(11):1085-1092 17.ChenJ.2004.InterspecificVariationofPlantTraitsAssociatedwithResistancetoHerbivoryAmongFourSpeciesofFicus(Moraceae).AnnalsofBotany94:377-384 118.NiuK,ZhangX,DengH,WuF,RenY,XiangH,ZhengS,LiuL,HuangL,ZengB,LiS,XiaQ,SongQ,R.PalliSandFengQ.2018.BmILFandi-motifstructureareinvolvedintranscriptionalregulationofBmPOUM2inBombyxmori.NucleicAcidsRes46(4):1710-1723. 19.XuG,ZhangJ,Lyu,H,SongQ,FengQ,XiangH,ZhengS.2018.DNAmethylationmediatesBmDeaf1-regulatedtissue-andstage-specificExpressionofBmCHSA-2binthesilkworm,Bombyxmori.EpigeneticsChromatin11(1):32. 20.ZhouZ,JiangY,WangZ,GouZ,LyuJ,LiW,YuY,ShuL,ZhaoY,MaY,FangC,ShenY,LiuT,LiC,LiQ,WuM,WangM,WuY,DongY,WanW,WangX,DingZ,GaoY,XiangH,ZhuB,LeeS,WangWandTianZ.2015.Resequencing302wildandcultivatedaccessionsidentifiesgenesrelatedtodomesticationandimprovementinsoybean.NatBiotechnol33(4):408-14 21Li,X,FanD,ZhangW,LiuG,ZhangL,ZhaoL,FangX,ChenL,DongY,ChenY,DingY,ZhaoR,FengM,ZhuY,FengY,JiangX,ZhuD,XiangH,FengX,LiS,WangJ,ZhangG,KronforsMR,WangW.2015.OutbredgenomesequencingandCRISPR/Cas9geneeditinginbutterflies.NatCommun6:8212. 22.ChenL,TangL,XiangH,JinL,LiQ,DongY,WangW,ZhangG.2014.Advancesingenomeeditingtechnologyanditspromisingapplicationinevolutionaryandecologicalstudies.GigaScience3:24. 23.ChenS,ZhangG,ShaoC,HuangQ,LiuG,ZhangP,SongW,AnN,ChalopinD,VolffJN,HongY,LiQ,ShaZ,ZhouH,XieM,YuQ,LiuY,XiangH,etal.2014.Whole-genomesequenceofaflatfishprovidesinsightsintoZWsexchromosomeevolutionandadaptationtoabenthiclifestyle.NatGenetdoi:10.1038/ng.2890 24.LiX,ZhuJ,HuF,GeS,YeM,XiangH,ZhangG,ZhengX,ZhangH,ZhangS,LiQ,LuoR,YuC,YuJ,SunJ,ZouX,CaoX,XieX,WangJ,WangW.2012.Single-baseresolutionmapsofcultivatedandwildricemethylomesandregulatoryrolesofDNAmethylationinplantgeneExpression.BMCGenomics13:300 25.BonasioR,LiQ,LianJ,MuttiNS,JinL,ZhaoH,ZhangP,WenP,XiangH,DingY,JinZ,ShenSS,WangZ,WangW,WangJ,BergerSL,LiebigJ,ZhangG,ReinbergD.2012.Genome-wideandcaste-specificDNAmethylomesoftheantsCamponotusfloridanusandHarpegnathossaltator.CurrBiol22:1755-1764 26.MiaoXX,XuSJ,LiMH,LiMW,HuangJH,DaiFY,MarinoSW,MillsDR,ZengP,MitaK,JiaSH,ZhangY,LiuWB,XiangH,GuoQH,XuAY,KongXY,LinHX,ShiYZ,LuG,ZhangX,HuangW,YasukochiY,SugasakiT,ShimadaT,NagarajuJ,XiangZH,WangSY,GoldsmithMR,LuC,ZhaoGP,HuangYP.2005.Simplesequencerepeat-basedconsensuslinkagemapofBombyxmori.ProcNatlAcadSciUSA102(45):16303-16308. 27.PengJY,LiZH,XiangH,HuangJH,JiaSH,MiaoXX,HuangYP.2005.Preliminarystudiesondifferentialdefenseresponsesinducedduringplantcommunication.CellResearch15(3):187-192.

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