龙程 - 华南师范大学 - 脑科学与康复医学研究所

个人简介

1994年在华南师范大学生物系获博士学位。1994-1996年在华东师范大学生物系从事博士后研究，1995-1997年任华东师范大学生物系副教授，1997-2004年先后在日本大阪市立大学理学部和美国南伊利诺斯州立大学医学院进行访问工作和博士后研究；2004年至2009，在美国贝勒医学院分子生理学和生物物理学系先后从事博士后研究和任Instructor；2010年受聘于华南师范大学生命科学学院，任教授、博导，生理学/神经生物学教研室主任，院学术委员会委员、校学术委员会（第七、八届）委员，广东省本科高校生物医学工程专业教学指导委员会委员，广东省侨联（第九、十届）委员。主持国家自然科学基金、广东省自然科学基金、广东省教育厅引智专项及广东省教育厅研究生示范课程等项目，曾参与多项美国NIH研究项目，在《Cell》、《eLife》、《Nature Communications》、《Cerebral Cortex》、《Hypertension》、《Arteriosclerosis, Thrombosis, and Vascular Biology》和《Cell Research》等国际著名杂志发表50多篇研究论文。参与翻译Biopsychology（ninth edition）《生物心理学》。目前主要运用膜片钳技术、细胞成像和生物化学方法研究神经退行性疾病和神经信号转导。为博士生、硕士生、本科生（勷勤创新班、生物科学或生物技术专业）讲授“离子通道学”、“现代神经生物学/生理学进展”、“高级神经生理学/生理学”、“细胞的跨膜信号转导”、“分子细胞生物学”、 “神经生物学/生理学实验技术”、“人体及动物生理学”、“人体解剖生理学”和“神经生理学”。

近期论文

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1. Chen M, Wang JZ, Zhang JX, Zheng XZ, Justice NJ, Wang K, Li Y, Huo QW, Zhang JJ, Li HM, Wang Y, Lu NN, Zheng H, Long C (龙程), Yang L*. (2017) APP modulates KCC2 expression and function in hippocampal GABAergic inhibition. eLife. 6: e20142. IF=8.303，生物学、医学双一区（*通讯作者） 2. Huo QW#, Chen M#, He QS, Zhang JJ, Li B, Jin K, Long C (龙程)*, Yang L*. (2016) Prefrontal cortical GABAergic dysfunction contributes to aberrant UP-state duration in APP knockout mice. Cerebral Cortex. 27(8): 4060-4072. IF=8.285，医学、神经科学双一区（*共同通讯作者） 3. Zhang JJ#, Hao CY#, Jiang JX#, Feng YJ, Chen X, Zheng Y, Liu JW, Zhang ZL, Long C(龙程), Yang L*. (2018) The mechanisms underlying olfactory deficits in apolipoprotein E-deficient mice: focuson olfactory epithelium and olfactory bulb. Neurobiology of Aging. 62: 20-33. IF=5.117, 医学、神经科学、老年医学二区（*通讯作者） 4. Cai ZL#, Zhang JJ#, Chen M, Wang JZ, Xiao P, Yang L*, Long C (龙程)*. (2016) Both pre- and post-synaptic defects contribute to aberrant cholinergic transmission in superior cervical ganglia of APP-/- mice. Neuropharmacology. 110 (Pt A): 493-502. IF=5.012，药学一区（*共同通讯作者） 5. Zhang J#, Chen M#, Li B, Lv BH, Jin K, Zheng SD, Yang L*, Long C (龙程)*. (2016) Altered striatal rhythmic activity in cylindromatosis knock-out mice due to enhanced GABAergic inhibition. Neuropharmacology. 100(Pt A): 260-267. IF=5.012，药学一区（*共同通讯作者） 6. Durham WJ#, Aracena-Parks P#, Long C (龙程)#, Rossi AE, Goonasekera SA, Boncompagni S, Galvan DL, Gilman1 CP, Baker M, Shirokova N, Protasi F, Dirksen R, Hamilton SL. (2008) RyR1 S-nitrosylation underlies environmental heat stroke and sudden death in Y522S RyR1 knock-in mice. Cell. 133: 53-65. IF: 34.366 7. Long C (龙程), Cook LG, Wu GY, Mitchell BM. (2007) Removal of FKBP12/12.6 from endothelial ryanodine receptors leads to an intracellular calcium leak and endothelial dysfunction. Arteriosclerosis, Thrombosis and Vascular Biology. 27: 1580-1586. IF: 7.221 8. Long C (龙程), Cook LG, Hamilton SL, Wu GY, Mitchell BM. (2007) FK506 binding protein 12/12.6 depletion increases endothelial nitric oxide synthase threonine 495 phosphorylation andblood pressure. Hypertension. 49: 569-576. IF: 7.368 9. Long C (龙程), Iino M. (2001) Light-dependent osmoregulation in pea stem protoplasts. photoreceptors, tissue specificity, ion relationships, and physiological implications.Plant Physiology. 125(4): 1854-1869. IF: 7.394 10. Long C (龙程)*, Wang XJ, Pan RC. (1998) The effect of external Ca2+ and Ca2+-channel modulators on red-light-induced swelling of protoplasts of Phaseolus radiatus L.Cell Research. 8(1): 41-50. IF（近5年平均）: 12.393 11. Long C (龙程)*, Wang XJ, Pan RC. (1995) The role of calcium ions in red light-induced swelling of mung bean protoplasts. Chinese Science Bulletin (科学通报). 40(3): 248-251. 12. Huo QW, Tabassum S, Misrani A, Long C (龙程)*. (2017) Recording EEG in freely moving neonatal rats with a novel method. Journal of Visualized Experiments (JoVE). 123: e55489. 13. Misrani A, Tabassum S, Long C (龙程)*. (2017) Oxytocin system in neuropsychiatric disorders: Old concept, new insights. Acta Physiologica Sinica. 69(2): 196–206. 14. Lee CS, Hanna AD, Wang H, Dagnino-Acosta A, Joshi AD, Knoblauch M, Xia Y, Georgiou DK, Martin JC, Xu J, Long C (龙程), Amano H, Reynolds C, Dong K, Lagor WR, Rodney GG, Sahin E, Sewry C, Hamilton SL. (2017) A chemical chaperone alleviates ER stress and improves muscle function in mice with an RyR1 mutation. Nature Communications. 8: 14659. IF: 11.329 15. Qi ZH, Wong CK, Suen CH, Wang JZ, Long C (龙程), Sauer H, Yao XQ, Tsang SY. (2016) TRPC3 regulates the automaticity of embryonic stem 2 cell-derived cardiomyocytes. International Journal of Cardiology. 203: 169-181. IF=4.638 16. Li M, Long C (龙程), Yang L. (2015) Hippocampal-prefrontal circuit and disrupted functional connectivity between the two structures in neuronal disorders. BioMed Research International. 2015: 810548. IF: 2.134 17. Chen HY, Xu DP, Tan GL, Cai W, Zhang GX, Cui W, Wang JZ, Long C (龙程), Sun YW, Yu P, Tsim KW, Zhang ZJ, Han YF, Wang YQ. (2015) A potent multi-functional neuroprotective derivative of tetramethylpyrazine. Journal of Molecular Neuroscience. 56(4): 977-987. IF=2.352 18. Lee CS, Dagnino-Acosta1 A, Yarotskyy V, Hanna A, Lyfenko A, Knoblauch M, Georgiou DK, Poché RA, Swank MW, Long C (龙程), Ismailov II, Lanner J,Tran T, Dong KK, Rodney GG, Dickinson ME, Beeton C, Zhang P, Dirksen RT, Hamilton SL. (2015) Ca2+ permeation and/or binding to CaV1.1 fine-tunes skeletal muscle Ca2+ signaling to improve muscle function. Skeletal Muscle. 5: 4. IF: 3.500 19. Lee CS, Georgiou DK, Dagnino-Acosta A, Xu J, Ismailov II, Knoblauch M, Monroe TO, Ji R, Hanna AD, Joshi AD, Long C (龙程), Oakes J, Tran T, Corona BT, Lorca S, Ingalls CP, Narkar VA, Lanner JT, Bayle JH, Durham WJ, Hamilton SL. (2014) Ligands for FKBP12 increase Ca2+ influx and protein synthesis to improve skeletal muscle function. The Journal of Biological Chemistry. 289(37): 25556-25570. IF: 4.651 20. 邓莉、王今朝、杨莉、龙程*。（2014）胆碱转运体与阿尔茨海默病。生物化学与生物物理进展。41(12): 1207-1213。（*通讯作者，SCI收录） 21. 王今朝、龙程、杨莉。（2014）小鼠主要脑区组织的优化急α性分离法。生理学报。66(2): 210-214。 22. 蔡昭林，肖鹏，龙程*。（2013）鞘脂类对胰岛素信号的调控——II型糖尿病研究的新兴领域。生物化学与生物物理进展。40(6): 495-500。（*通讯作者，SCI收录） 23. 龙程*。脑研究的进展、挑战与机遇。华南师范大学学报, 2013, 45 (6): 161-164。（*通讯作者） 24. 霍清伟，李东风，龙程*。（2012）多聚二磷酸腺苷聚合酶1与动脉粥样硬化。生物化学与生物物理进展。39(5): 423-428。（*通讯作者，SCI收录） 25. Chen MF, Huang YC, Long C (龙程), Yang HI, Lee HC, Chen PY, Hoffer BJ, Lee TJ. (2012) Bimodal effects of fluoxetine on cerebral nitrergic neurogenic vasodilation in porcine large cerebral arteries. Neuropharmacology. 62(4): 1651-1658. IF: 5.012