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个人简介

1995/09-1999/07四川大学生命学院,生物化学,学士 1999/09-2002/07四川大学生命学院,生物化学与分子生物学,硕士 2002/12-2007/05香港大学动物学系,动物学专业,博士 2007/06-2011/07电子科技大学生命科学与技术学院,讲师 2011/08-至今电子科技大学生命科学与技术学院,副教授/硕士生导师 教学工作 本科生:生物化学 研究生:高级生物化学

研究领域

1.细胞因子在鱼类免疫系统中的调控及作用机制 2.转录因子剪接异构体在鱼类免疫调节中的生理意义 3.粘附分子在鱼类免疫系统中的作用及调节机理

近期论文

查看导师新发文章 (温馨提示:请注意重名现象,建议点开原文通过作者单位确认)

01.WangXinyan,YangXiao,WenChao,GaoYajun,QinLei,ZhangShengnan,ZhangAnying,YangKun,ZhouHong.GrasscarpTGF-β1impairsIL-1βsignalingintheinflammatoryresponses:EvidenceforthepotentialofTGF-β1toantagonizeinflammationinfish.DevCompImmunol.2016;59:121-7 02.WangXinyan,GuoYafei,WeiHe,WangKe,ZhangAnying,ZhouHong.RegulatoryrolesofgrasscarpEpCAMincellmorphology,proliferationandmigration.FishPhysiolBiochem.2016;42(2):423-30. 03.WangXinyan,WeiHe,ZhaoTaiqiang,ZhuXiaojing,YangXiao,ChenDanyan,ZhouHong.Evidenceforpituitaryadenylatecyclase-activatingpeptideasadirectimmunoregulatorinteleostheadkidney.FishShellfishImmunol2013;34(1):265-72. 04.ZhaoTaiqiang,WangXinyan,WeiHe,YangMu,ZengFancai,ZhouHong,Molecularandfunctionalcharacterizationofgrasscarpsquint/nodal-related1:apotentialregulatorofactivinsignalinginteleostpituitarycells.DomestAnimEndocrinol2012;42,239-248.(共同一作) 05.XinyanWang,TaiqiangZhao,HeWei,HongZhou.RegulationofdopamineD2receptorexpressioningrasscarppituitarycells:Apossiblemechanismfordopaminergicmodificationofluteinizinghormonesynthesis.GenCompEndocrinol2011;173(1):48-55. 06.WangXinyan,WangYanan,YangMu,ZhouHong.Anewlyidentifiedepithelialcelladhesionmolecule(EpCAM)fromgrasscarp(Ctenopharyngodonidellus):cloning,tissuedistributionandlipopolysaccharide-inducedexpressioninheadkidneyleucocytes.FishShellfishImmunol2010;29(6):998-1002. 07.WangXinyan,Mable,ChuM.S.,Anderson,WongA.O.Signalingmechanismsforalpha2-adrenergicinhibitionofPACAP-inducedgrowthhormonesecretionandgeneexpressiongrasscarppituitarycells.AmJPhysiolEndocrinolMetab2007;292(6):E1750-62. 08.YangMu,WangXinyan,Chen,Danyan,WangYanan,ZhangAnying,ZhouHong,TGF-beta1exertsopposingeffectsongrasscarpleukocytes:implicationinteleostimmunity,receptorsignalingandpotentialself-regulatorymechanisms.PLoSOne2012;7(4):e35011.Epub2012Apr17. 09.ZhangAnying,ZhouXiaofei,WangXinyang,ZhouHong.Characterizationoftwoheatshockproteins(Hsp70/Hsc70)fromgrasscarp(Ctenopharyngodonidella):evidencefortheirdifferentialgeneexpression,proteinsynthesisandsecretioninLPS-challengedperipheralbloodlymphocytes.CompBiochemPhysiolBBiochemMolBiol2011;159(2):109-14 10.SongChunlei,WangXinyan,ZhouHong.MolecularcloningofactivintypeIandtypeIIreceptorsanddifferentialregulationoftheirexpressionbyactiviningrasscarppituitarycells.GenCompEndocrinol2010;166(1):211-6. 11.ChenChao,SongChunlei,WangXinyan,ZhouHhong.Molecularcloning,characterizationandtissuedistributionofsixsplicevariantsofactivintypeIIAreceptor(ActRIIA)fromgrasscarp(Ctenopharyngodonidellus).GenesGenetSyst2009;84(5):335-44. 12.JiangQuan,HeMulan,WangXinyan,Anderson,WongA.O.Grasscarpsomatolactin:II.PharmacologicalstudyonpostreceptorsignalingmechanismsforPACAP-inducedsomatolactin-alphaand-betageneexpression.AmJPhysiolEndocrinolMetab2008;295(2):E477-90. 13.HuoLongfeiFuGuodong,WangXinyan,Wendy,KoK.W.,Anderson,WongA.O.Modulationofcalmodulingeneexpressionasanovelmechanismforgrowthhormonefeedbackcontrolbyinsulin-likegrowthfactoringrasscarppituitarycells.Endocrinology2005;146(9):3821-35. 14.ZhouHong,WangXinyan,Wendy,KoK.W.,andAnderson,WongA.O.Evidenceforanovelintrapituitaryautocrine/paracrinefeedbackloopregulatinggrowthhormonesynthesisandsecretioningrasscarppituitarycellsbyfunctionalinteractionsbetweengonadotrophsandsomatotrophs.Endocrinology2004;145(12):5548-59. 15.WeiHe,YangMu,ZhaoTaiqiang,WangXinyan,ZhouHong.FunctionalexpressionandcharacterizationofgrasscarpIL-10:AnessentialmediatorofTGF-β1immuneregulationinperipheralbloodlymphocytes.MolImmunol2012;53(4):313-320.

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