个人简介
教育背景
2000.09-2004.06山东大学化学与化学工程学院,应用化学,学士
2004.09-2009.06山东大学药学院,药物化学,博士
工作经历
2009.09-2012.04美国圣尤大儿童研究医院,博士后
2012.04-2016.08美国艾默里大学,博士后
2016.09-2018.09暨南大学环境学院,研究员
2018.10-至今广州大学大湾区环境研究院,教授
科研项目
1)国家自然科学基金重大研究计划培育项目,90913006,选择性治疗耐药性肺癌的噻唑烷酮类小分子探针的设计、合成及体外抗癌活性研究与机制探讨,2010/01-2012/12,已结题,参加;
2)暨南大学培育与跃升计划,21617445,金纳米颗粒库的快速高通量构建及其生物效应,2017/01-2018/12,主持,结题;
3)国家自然科学基金重大研究计划培育项目,91743107,细颗粒物多组分混合暴露的联合毒性机制研究,2018/01-2020/12,主持,进行中;
研究领域
基于人类细胞组合的污染物健康效应评价;基于PM2.5人工模型的大气颗粒物致毒机制研究;环境污染物生物效应的构效关系及预测模型
近期论文
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1)GouY,MiaoDD,ZhouM,WangLJ,ZhouHY*,SuGX*.Bio-InspiredProtein-basednanoformulationsforCancerTheranostics.Front.Pharmacol.2018,9,421.
2)LiuY,SuGX,WangF,JiaJB,LiSH,ZhaoLL,ShiYL,CaiYQ,ZhuH,ZhaoB,JiangGB,ZhouHY*,YanB*.ElucidationoftheMolecularDeterminantsforOptimalPerfluorooctanesulfonateAdsorptionUsingaCombinatorialNanoparticleLibraryApproach,Environ.Sci.Technol.2017,51(12),7120-7127.
3)SuGX#,ZhouXF#,ZhouHY*,LiY,ZhangXR,LiuY,CaoDP,YanB.*Size-DependentFacilitationofCancerCellTargetingbyProteinsAdsorbedonNanoparticles.ACSAppl.Mater.Interfaces2016,8,30037–30047.
4)ZhouHY,QianWP,UckunF.M,WangLY,WangA.Y,ChenHY,KoobyD,YuQ,LipowskaM,StaleyC.A,MaoH,YangL*IGF1ReceptorTargetedTheranosticNanoparticlesforTargetedandImage-guidedTherapyofPancreaticCancer.ACSNano,2015,9,7976–7991.
5)ZhouHY,SuGX,JiaoPF,YanB.*Acceleratingmultifunctionalizationoftheranosticnanoparticlesusingmulticomponentreaction.Chem.Eur.J.2012,18,5501-5505.
6)ZhouHY,JiaoPF,YangL,LiX,YanB.*EnhancingCellRecognitionbyScrutinizingCellSurfaceswithaNanoparticleArray.J.Am.Chem.Soc.2011,133,680–682.
7)ZhouHY,LiX,LemoffA,ZhangB,YanB.*StructuralConfirmationandQuantificationofIndividualLigandsfromtheSurfaceofMulti-FunctionalizedGoldNanoparticles.Analyst,2010,135,1210-1213.
8)DuFF#,ZhouHY#(共同第一作者),ChenLQ,ZhangB,YanB.*StructureElucidationofNanoparticle-BoundOrganicMoleculesBy1HNMR.TRAC-TrendsAnal.Chem.2009,28,88-95.
9)ZhouHY,MuQX,GaoNN,LiuAF,XingYH,GaoSL,ZhangQ,QuGB,ChenYY,LiuG,ZhangB,YanB.*ANano-CombinatorialLibraryStrategyfortheDiscoveryofNanotubeswithReducedProtein-Binding,Cytotoxicity,andImmuneResponse.NanoLett.2008,8,859-865.
10)ZhouHY,WuSH,ZhaiSM,LiuAF,SunY,LiRS,ZhangY,EkinsS,SwaanPW,FangB,ZhangB,YanB.*Design,Synthesis,CytoselectiveToxicity,Structure-ActivityRelationships,andPharmacophoreofThiazolidinoneDerivativesTargetingDrug-ResistantLungCancerCells.J.Med.Chem.2008,51,1242-1251(HighlightedbyDrugDiscoveryToday,13,1107-1108,2008.).