闫兵 - 广州大学 - 大湾区环境研究院

个人简介

教育背景 1978.02-1982.01 山东大学化学系，学士 1986.09-1989.10 美国哥伦比亚大学，M.A. 1986.09-1990.10 美国哥伦比亚大学，M.Phil. 1989.09-1990.10 美国哥伦比亚大学，Ph.D. 工作经历 1993.07-1999.07 美国Novartis Pharmaceutical Corporation, Summit, New Jersey, Senior Associate Fellow 1999.07-2004.03 美国Discovery Partners International, South San Francisco, California，分析科学部主任 2004.03-2005.11 美国Bristol-Myers Squibb Biomedical Research Institute, Wallingford, Connecticut, Senior Principle Scientist 2007-2012 美国St. Jude Children’s Research Hospital，Memphis, Tennesse, 教授，高通量新药研发分析中心主任 2005.11-2017.09 山东大学化学与化工学院及环境科学与工程学院，特聘教授 2017 - 至今广州大学大湾区环境研究院环境污染与健康团队，特聘教授

研究领域

环境毒理、微纳米材料毒理效应、化学生物学

近期论文

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Mu Q, Jiang G, Chen L, Zhou H, Fourches D, Tropsha A & Yan B.*, Chemical Basis of Interactions Between Engineered Nanoparticles and Biological Systems. Chemical Reviews 2014, 114(15):7740-81. Zhang Y, Bai Y, Jia J, Gao N, Li Y, Zhang R, Jiang G, Yan B.*, Perturbation of Physiological Systems by Nanoparticles. Chemical Society Reviews 2014, 28(3):296-305. Wang Y, Yan B, Chen L. SERS Tags: Novel Optical Nanoprobes for Bioanalysis. Chemical Reviews 2013, 113(3), 1391-1428. Bai Y, Zhang Y, Zhang J, Mu Q, Zhang W, Butch E, Snyder S, Yan B.* Repeated carbon nanotube administrations in male mice cause reversible testis damage without affecting fertility. Nature Nanotechnology 2010, 5(9), 683-689. Jiao P, Zhou H, Otto M, Mu Q, Li L, Su G, Zhang Y, Butch E, Snyder S, Jiang G, Yan B.* Leading Neuroblastoma Cells to Die by Multiple Premeditated Attacks from a Multifunctionalized Nanoconstruct. Journal of the American Chemical Society 2011, 133(35), 13918-13921. Li L, Zhang Q, Liu A, Li X, Zhou H, Liu Y, Yan B.* Proteome Interrogation Using Nanoprobes to Identify Targets of a Cancer-killing Molecule. Journal of the American Chemical Society 2011, 133(18), 6886-6889. Zhou H, Jiao P, Yang L, Li X, Yan B.* Enhancing Cell Recognition by Scrutinizing Cell Surfaces with a Nanoparticle Array. Journal of the American Chemical Society 2011, 133(4), 680-682. Wang W, Sedykh A, Sun H, Zhao L, Russo D, Zhou H, Yan B*, Zhu H*. Predicting Nano-bio Interactions by Integrating Nanoparticle Libraries and Quantitative Nanostructure Activity Relationship Modeling. ACS Nano. 2017. 11 (12) :12641–12649. Gao N, Zhang Q, Mu Q, Bai Y, Li L, Zhou H, Butch E, Powell T, Snyder S, Jiang G, Yan B*, Steering Carbon Nanotubes to Scavenger Receptor Recognition by Nanotube Surface Chemistry Modification Partially Alleviates NFκB Activation and Reduces Its Immunotoxicity. ACS Nano 2011, 5(6), 4581-4591. Wu L, Zhang Y, Zhang C, Cui X, Zhai S, Liu Y, Li C, Zhu H, Qu G, Jiang G, Yan B.* Tuning Cell Autophagy by Diversifying Carbon Nanotube’s Surface Chemistry. ACS Nano, 2014, 8(3): 2087-99. Mu Q, Du G, Chen T, Zhang B, Yan B.* Suppression of Human Bone Mophorgenetic Protein (BMP) Signaling by Carboxylated Single-Walled Carbon Nanotubes. ACS Nano 2009, 3(5), 1139-1144. Mu Q, Broughton D, Yan B.* Endosomal Leakage and Nuclear Translocation of Multiwalled Carbon Nanotubes: Developing a Model for Cell Uptake. Nano Letters 2009, 9(12), 4370-4375. Zhang B, Xing Y, Zhou H, Li Z, Mu Q, Yan B.* Functionalized Carbon Nanotubes Specifically Bind to Chymotrypsin Catalytic Site and Regulate its Enzymatic Function. Nano Letters 2009, 9(6), 2280-2284. Zhou H, Mu Q, Gao N, Liu A, Xing Y, Gao S, Zhang Q, Qu G, Chen Y, Liu G, Zhang B, Yan B*. A Nano-Combinatorial Library Strategy for the Discovery of Nanotubes with Reduced Protein-Binding, Cytotoxicity, and Immune Response. Nano Letters 2008, 8(3), 859-865. Zhang Y, Wang Y, Liu A, Xu L, Zhao B, Zhang Y, Zou H, Wang W, Zhu H and Yan B.*, Modulation of Carbon Nanotube’s Perturbation to the Metabolic Activity of CYP3A4 in the Liver, Advanced Functional Materials 2016, 26:841-850.