曲广波 - 中国科学院大学 - 资源与环境学院

个人简介

招生专业 0703J1-纳米科学与技术 0703Z1-化学生物学 100102-免疫学招生方向环境污染与健康新型污染物分析污染物与生物效应教育背景 2008-09--2011-06 中国科学院生态环境研究中心理学博士 2000-09--2004-07 黑龙江大学生命科学学院理学学士工作简历 2015-03~2015-05,美国迈阿密大学米勒医学院, 访问学者，博士后 2015-01~现在, 中国科学院生态环境研究中心, 副研究员 2014-01~2015-02,美国印第安纳大学医学院, 访问学者，博士后 2011-07~2014-12,中国科学院生态环境研究中心, 助理研究院 2010-07~2011-02,香港科技大学化学系, 研究助理 2005-09~2008-07,山东大学药学院, 医学硕士教授课程纳米毒理学科研项目（ 1 ）稀土氧化物纳米材料对DNA甲基化和羟甲基化的调控机理及其毒性研究, 主持, 国家级, 2016-01--2019-12 （ 2 ）纳米银对巨噬细胞毒性的机理研究, 主持, 国家级, 2013-01--2015-12 （ 3 ）典型污染物的环境暴露与健康危害机制, 参与, 部委级, 2014-07--2019-07 （ 4 ）典型人工纳米材料的水环境过程、生物效应及其调控研究, 参与, 国家级, 2014-01--2019-12 （ 5 ）化学环境污染与健康, 主持, 国家级, 2018-01--2020-12 参与会议（1）Neural toxicity assay-directed analysis: application in novel pollutant identification 2012-09-23

近期论文

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（1） High-resolution mass spectrometry (HRMS) methods for nontarget discovery and characterization of poly- and per-fluoroalkyl substances (PFASs) in environmental and human samples, Trends in Analytical Chemistry, 2019-02, 通讯作者（2） Improved Biocompatibility of Black Phosphorus Nanosheets by Chemical Modification, Angewandte Chemie International Edition, 2017, 第 1 作者（3） Determining the Cytotoxicity of Rare Earth Element Nanoparticles in Macrophages and the Involvement of Membrane Damage, Environmental Scicence & Technology, 2017, 通讯作者（4） Structure-Dependent Hematological Effects of Per- and Polyfluoroalkyl Substances on Activation of Plasma Kallikrein-Kinin System Cascade, Environmental Science & Technology, 2017, 第 3 作者（5） Distinct toxicological characteristics and mechanisms of Hg(2+) and MeHg in Tetrahymena under low concentration exposure, Aquatic Toxicology, 2017, 第 2 作者（6） Identification of Emerging Brominated Chemicals as the Transformation Products of Tetrabromobisphenol A (TBBPA) Derivatives in Soil, Environmental Science & Technology, 2017, 通讯作者（7） Sensitive immunoassay for simultaneous determination of tetrabromobisphenol A bis(2-hydroxyethyl) ether and tetrabromobisphenol A mono(hydroxyethyl) ether: An effective and reliable strategy to estimate the typical tetrabromobisphenol A derivative and byproduct in aquatic environments, Environmental Pollution, 2017, 通讯作者（8） A crucial role of heme-regulated eIF2 alpha kinase in maintaining cytoskeletal meshwork under an oxygen deficient condition, Science Bulletin, 2017, 第 1 作者（9） Recent advances in the analysis of TBBPA/TBBPS, TBBPA/TBBPS derivatives and their transformation products, Trends in Analytical Chemistry, 2016, 第 1 作者（10） Graphene enhances cellular proliferation through activating EGFR, Journal of Agricultural and Food Chemistry, 2016, 第 6 作者（11） The potential neurotoxicity of emerging tetrabromobisphenol A derivatives based on rat pheochromocytoma cells, Chemosphere, 2016, 第 5 作者（12） Carbon nanotubes stimulate synovial inflammation through inducing systemic pro-inflammatory cytokines, Nanoscale, 2016, 第 3 作者（13） Tetrabromobisphenol-A/S and Nine Novel Analogs in Biological Samples from the Chinese Bohai Sea: Implications for Trophic Transfer, Environmental science & technology, 2016, 第 2 作者（14） Exposure, Tissue Biodistribution, and Biotransformation of Nanosilver, NanoImpact, 2016, 第 3 作者（15） Silver ion post-column derivatization electrospray ionization mass spectrometry for determination of tetrabromobisphenol A derivatives in water samples, RSC Advances, 2015, 第 3 作者（16） Identification of two novel brominated contaminants in water samples by ultra-high performance liquid chromatography-Orbitrap Fusion Tribrid mass spectrometer, Journal of Chromatography A, 2015, 第 2 作者（17） Reactive extractive electrospray ionization tandem mass spectrometry for sensitive detection of tetrabromobisphenol A derivatives, Analytica chimica acta, 2014, 第 4 作者（18） Graphene Oxide Induces Toll-like Receptor 4 (TLR4)-Dependent Necrosis in Macrophages, ACS Nano, 2013, 第 1 作者（19） Identification of Tetrabromobisphenol A Allyl Ether and Tetrabromobisphenol A 2,3-Dibromopropyl Ether in the Ambient Environment near a Manufacturing Site and in Mollusks at a Coastal Region, Environmental Science & Technology, 2013, 第 1 作者（20） Evaluation of the biological fate and the transport through biological barriers of nanosilver in mice, Current pharmaceutical design, 2013, 第 2 作者（21） The capability of quantum dots in crossing the placental barrier and the potential influence on erythrocytes, Journal of nanoscience and nanotechnology, 2013, 第 3 作者（22） Quantum dots (QDs) restrain human cervical carcinoma HeLa cell proliferation through inhibition of the ROCK-c-Myc signaling, Integrative Biology, 2013, 第 1 作者（23） Downregulation of ubiquitin E3 ligase TNF receptor-associated factor 7 leads to stabilization of p53 in breast cancer, Oncology reports, 2013, 第 4 作者（24） Characterization of the interaction between cadmium and chlorpyrifos with integrative techniques in incurring synergistic hepatoxicity, PloS one, 2013, 第 2 作者（25） Simultaneous determination of five estrogens and four androgens in water samples by online solid-phase extraction coupled with high-performance liquid chromatography–tandem mass spectrometry, Journal of chromatography A, 2013, 第 3 作者（26） A protective role of heme-regulated eIF2α kinase in cadmium-induced toxicity in erythroid cells, Food and chemical toxicology, 2013, 第 4 作者（27） Influence of e-waste dismantling and its regulations: temporal trend, spatial distribution of heavy metals in rice grains, and its potential health risk, Environmental science & technology, 2013, 第 4 作者（28） The ex vivo and in vivo biological performances of graphene oxide and the impact of surfactant on graphene oxide's biocompatibility, Journal of Environmental Sciences, 2013, 第 1 作者（29） Cytotoxicity of quantum dots and graphene oxide to erythroid cells and macrophages, Nanoscale research letters, 2013, 第 1 作者（30） Silver nanoparticles induced RNA polymerase-silver binding and RNA transcription inhibition in erythroid progenitor cells, ACS nano, 2013, 第 4 作者（31） Quantum dots impair macrophagic morphology and the ability of phagocytosis by inhibiting the Rho-associated kinase signaling, Nanoscale, 2012, 第 1 作者（32） Sample preparation method for the speciation of polybrominated diphenyl ethers and their methoxylated and hydroxylated analogues in diverse environmental matrices, Talanta, 2012, 第 4 作者（33） Temporal trends (2005–2009) of PCDD/Fs, PCBs, PBDEs in rice hulls from an e-waste dismantling area after stricter environmental regulations, Chemosphere, 2012, 第 4 作者（34） Identification of Tetrabromobisphenol A Diallyl Ether as an Emerging Neurotoxicant in Environmental Samples by Bioassay-Directed Fractionation and HPLC-APCI-MS/MS, Environmental Science & Technology, 2011, 第 1 作者（35） Detection of tris-(2, 3-dibromopropyl) isocyanurate as a neuronal toxicant in environmental samples using neuronal toxicity-directed analysis, Science China Chemistry, 2011, 第 1 作者（36） The effect of multiwalled carbon nanotube agglomeration on their accumulation in and damage to organs in mice, Carbon, 2009, 第 1 作者