研究领域
研究领域包括不对称合成方法学及手性药物合成、复杂天然产物全合成研究(海洋生物碱和甾体)、绿色化学过程研究。
近期论文
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“Samarium Diiodide-Induced Asymmetric Synthesis of Optically Pure Unsymmetrical Vicinal Diamines by Reductive Cross-Coupling of Nitrones with N-tert-Butanesulfinyl Imines” Yu-Wu Zhong, Ming-Hua Xu*, Guo-Qiang Lin Org. Lett. 2004, 6, 3953.
“Highly Diastereoselective and Enantioselective Synthesis of Enantiopure C2-Symmetrical Vicinal Diamines by Reductive Homocoupling of Chiral N-tert-Butanesulfinyl Imines” Yu-Wu Zhong, Kenji Izumi, Ming-Hua Xu*, Guo-Qiang Lin Org. Let. 2004, 6, 4747.
“A Highly Efficient and Direct Approach for Synthesis of Enantiopure -Amino Alcohols by Reductive Cross-Coupling of Chiral N-tert-Butanesulfinyl Imines with Aldehydes” Yu-Wu Zhong, Yi-Zhou Dong, Kai Fang, Kenji Izumi, Ming-Hua Xu*, Guo-Qiang Lin* J. Am. Chem. Soc. 2005, 127, 11956.
“Room-Temperature Highly Diastereoselective Zn-Mediated Allylation of Chiral N-tert-Butanesulfinyl Imines: Remarkable Teaction Condition Controlled Stereoselectivity Reversal” Xing-Wen Sun, Ming-Hua Xu*, Guo-Qiang Lin* Org. Lett. 2006, 8, 4979.
“Total Synthesis of Phorboxazole B” De-Run Li, Dong-Hui Zhang, Cai-Yun Sun, Ji-Wen Zhang, Li Yang, Jian Chen, Bo Liu, Ce Su, Weishan Zhou*, Guo-Qiang Lin* Chem. Eur. J. 2006, 12, 1185.
“Design of C2-Symmetric Tetrahydropentalenes as New Chiral Diene Ligands for Highly Enantioselective Rh-Catalyzed Arylation of N-Tosylarylimines with Arylboronic Acid” Zhi-Qian Wang, Chen-Guo Feng, Ming-Hua Xu*, Guo-Qiang Lin* J. Am. Chem. Soc. 2007, 129, 5336.
“Facile Synthesis of Alkyl -D-glucopyranosides from D-glucose and the corresponding alcohols using fruit seed meals” Wen-Ya Lu, Guo-Qiang Lin*, Hui-Lei Yu, Ai-Ming Tong, Jian-He Xu* J. Mol. Cat. B: Enzymatic 2007, 44, 72.