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研究领域

小分子活化,水裂解,甲烷氧化; 过渡金属催化的高选择性反应研究; 不对称催化,催化剂设计以及反应机理研究; 电化学在金属有机化学中的应用。

近期论文

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Mei, T.-S.; Patel, H. H.; Sigman, M. S. “Enantioselective construction of remote quaternary stereocentres” Nature 2014, 508, 340–344. Mei, T.-S.; Werner, E. W.; Burckle, A. J.; Sigman, M. S. “Enantioselective Redox-Relay oxidative Heck Arylations of Acyclic Alkenyl Alcohols using Boronic Acids” J. Am. Chem. Soc. 2013, 135, 6830–6833. Mei, T.-S.; Leow, D.; Xiao, H.; Laforteza, B.; Yu, J.-Q. “Synthesis of Indolines via Pd(II)-Catalyzed Amination of C–H Bonds” Org. Lett. 2013, 15, 3058–3061. Werner, E. W.; Mei, T.-S.; Burckle, A. J.; Sigman, M. S. “Enantioselective Heck arylations of acyclic alkenyl alcohols using a redox-relay strategy” Science 2012, 338, 1455–1458. Leow, D.; Li, G.; Mei, T.-S.; Yu, J.-Q. “Activation of remote meta-C–H Bonds assisted by an 'end-on' template” Nature 2012, 486, 518–522. Mei, T.-S.; Kou, L.; Engle, K. M.; Yu, J.-Q. “Construction of heterocycles via Pd-catalyzed C–H funtionalization ” Synthesis 2012, 44, 1778–1791. Mei, T.-S.; Wang, D.-H.; Yu, J.-Q. “Expedient drug synthesis and diversification via ortho-C–H iodination using recyclable PdI2 as the precatalyst” Org. Lett. 2010, 12, 3140–3143. Mei, T.-S.; Wang, X.; Yu, J.-Q. “Pd(II)-catalyzed amination of C–H bonds using single-electron or two-electron oxidants” J. Am. Chem. Soc. 2009, 131, 10806–10807. Mei, T.-S.; Giri, R.; Maugel, N.; Yu, J.-Q. “PdII-catalyzed monoselective ortho-halogenation of C–H bonds assisted by counter cations: a complementary method to directed ortho-lithiation” Angew. Chem. Int. Ed. 2008, 47, 5215–5219. Mei, T.-S.; Peng, L.-Z.; Zhang, T.; Li, Y.-L. “A concise and stereoselective synthesis of cathasterone’s side chain” Chin. Chem. Lett. 2004, 15, 762–764.

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