近期论文
查看导师新发文章
（温馨提示：请注意重名现象，建议点开原文通过作者单位确认）
1.TaipingGan,YujiWang,MingZhao,JianhuiWu,JianYang,ShiqiPeng.,5-(Bis(3-(2-hydroxyethyl)-1H-indol-2-yl)methyl)-2-hydroxybenzoicacid(BHIMHA):showingastrategyofdesigningdrugtoblocklungmetastasisoftumors.DrugDesign,DevelopmentandTherapy2016,10:711-721.SCI
2.XiHu,MingZhao,YujiWang,YaonanWang,ShuruiZhao,JianhuiWu,XiangminLiandShiqiPeng,Tetrahydro-b-carboline-3-carboxyl-thymopentin:anano-conjugateforreleasingpharmacophorestotreattumorandcomplications.J.Mater.Chem.B,2016:4,1384-1397.SCI
3.XuWenyun,ZhaoMing,WangYuji,Zhuhaimei,WangYaonan,ZhaoShurui,WuJianhui,PengShiqi,Design,synthesis,andinvivoevaluationsofbenzylNω-nitro-Nα-(9H-pyrido[3,4-b]indole-3-carbonyl)-L-argininateasanapoptosisinducercapableofdecreasingtheserumconcentrationofP-selectin.Medchemcomm,2016,7,1730SCI
4.NingSong,MingZhao,YujiWang,XiHu,JianhuiWu,XueyunJiang,ShanLi,ChunyingCui,ShiqiPeng1Nanomedicalstrategytoprolongsurvivalperiod,heightencurerate,andlowersystemictoxicityofs180micetreatedwithmtx/mit..DrugDesignDevelopment&Therapy,Volume10,2701-2711.SCI
5.QiqiFeng,MingZhao*,TaipingGan,HaimeiZhu,YaonanWang,ShuruiZhao,YujiWang,JianhuiWuandShiqiPeng*.DHDMIQK(KAP):anovelnano-deliverysystemofdihydroxyl-tetrahydro-isoquinoline-3-carboxylicacidandKPAKtowardsthethrombus.JournalofMaterialsChemistryB.2016.4.5991-6003.SCI
6.JianhuiWu1，YujiWang1，YaonanWang1，MingZhao1,2，XiaoyiZhang1，LinGui1，ShuruiZhao1，HaimeiZhu1，JinghuaZhao1，ShiqiPeng1，Cu2+-RGDFRGDS:exploringthemechanismandhighefficacyofthenanoparticleinantithrombotictherapy，InternationalJournalofNanomedicine2015:102925–29384.383
7.YujiWang,JingchengTang,HaimeiZhu,XueyunJiang,JiawangLiu,WenyunXu,HaipingMa,QiqiFeng,JianhuiWu,MingZhao,ShiqiPeng.AqueousextractofRabdosiarubescensleaves:formingnanoparticles,targetingP-selectin,andinhibitingthrombosis.InternationalJournalofNanomedicine2015:101–144.383
8.ShanLi,1YujiWang,1FengWang,1YaonanWang,1XiaoyiZhang,1MingZhao,1,2QiqiFeng,1JianhuiWu,1ShuruiZhao,1WeiWu,3ShiqiPeng1，SmallmoleculePZL318:formingfluorescentnanoparticlescapableoftracingtheirinteractionswithcancercellsandactivatedplatelets,slowingtumorgrowthandinhibitingthrombosis，InternationalJournalofNanomedicine2015:105273–52924.383
9.FengWanga,ShanLia,YujiWanga,HaimeiZhua,XiaoyiZhanga,MingZhao*ab,JianhuiWuaandShiqiPeng*a，Enantiomericdiketopiperazines:gettinginsightintotheimpactoftheconfigurationontheconformation,nanoimage,u-PAinhibitionandanti-metastaticactivity†，Med.Chem.Commun.,2015,6,956-962封面文章2.495
10.XueyunJiang,YujiWang,HaimeiZhu,YaonanWang,MingZhao,ShuruiZhao,JianhuiWu,ShanLi,ShiqiPeng,Modifyingtetramethyl-nitrophenyl-imidazolinewithaminoacids:Design,synthesisand3D-QSARforimprovinginflammatorypaintherapy.DrugDesDevTher,2015,9,2329-2342.IF=3.026
11.ShanLi,YujiWang,MingZhao,JianhuiWu,ShiqiPeng,BPIC:Anovelanti-tumorleadcapableofinhibitinginflammationandscavengingfreeradicals.BioorgMedChemLett,2015,25,1146-1150.IF=2.331
12.ShuanglingChen,YujiWang,ShanLi,YaonanWang,MingZhao,HaimeiZhu,JianhuiWu,ShiqiPeng,Poly-α,β-aspartyl-Arg-Gly-Asp-Phe:Anovelpolymericnanomedicine.MedChemComm2015,6,182-186.2.495封面文章
13.ChunyingCui,YujiWang,YaonanWang,JunyuYang,JianzhongXi,MingZhao,ShiqiPeng,PreparationandcharacterizationofRGDS/nanodiamondasavectorforVEGF-siRNAdelivery.J.Biomed.Nanotechnol.,2015,11,70-80.（IF=7.578）
14.ChunyingCui,aYaonanWang,aWenZhao,aKaikaiYang,aXueyunJiang,aShanLi,aMingZhao,*abYuanboSongcandShiqiPeng*a，RGDScovalentlysurfacednanodiamondasatumortargetingcarrierofVEGF-siRNA:synthesis,characterizationandbioassay，J.Mater.Chem.B，DOI:10.1039/c5tb01602aIF=4.726
15.MinnaLi,aYujiWang,aYutongYang,aYeqingGao,aMingZhao,*a,bMeiqingZhengaandShiqiPeng*a，Oximatedrutheniumtris-bipyridylcomplex:synthesisandluminescentresponsespecificallyforClO−inwatercontainingmultipleions，DaltonTrans.,2015,44,14071–140764.197
16.HualongYu,ShenghuiMei,LiZhao,MingZhao,*YujiWang,HaimeiZhu,YaonanWang,JianhuiWu,ChunyingCui,WenyunXuandShiqiPeng*，RGD-peptidesmodifyingdexamethasone:toenhancetheanti-inflammatoryefficacyandlimittheriskofosteoporosis†，Med.Chem.Commun.,2015,6,1345-13512.495
17.WenhuaZhao,YujiWang,WeijiaHao,MingZhao*,ShiqiPeng*.Preparativeisolationandpurificationofurolithinsfromtheintestinalmetabolitesofpomegranateellagitanninsbyhigh-speedofpomegranateellagitanninsbyhigh-speedchromatography.JournalofChromatographyB,2015,990:111-1172.694
18.HaimeiZhu,YuanboSong,YujiWang,MingZhao,*YiRen,YaonanWang,ShuruiZhao,JianhuiWu,ShiqiPeng*,Design,synthesisandevaluationofnovelπ-πstackingnano-intercalatorasanti-tumoragent†,Med.Chem.CommunDOI:10.1039/C5MD00507HIF=2.495
19.XiHu,MingZhao,*YujiWang,YaonanWang,ShuruiZhao,JianhuiWu,XiangminLi,andShiqiPeng,*,Tetrahydro-β-carboline-3-carboxyl-thymopentin:Anano-conjugateforreleasingpharmacophorestotreattumorandcomplications.JournalofMaterialsChemistryB.DOI:10.1039/x0xx00000x4.726
20.TaipingGan,YujiWang,MingZhao*,JianhuiWu,JianYang,andShiqiPeng*,5-(Bis(3-(2-hydroxyethyl)-1H-indol-2-yl)methyl)-2-hydroxybenzoicacid(BHIMHA):Showingastrategyofdesigningdrugtoblocklungmetastasisoftumors,DrugDesign,DevelopmentandTherapy.2015，已接受3.028
21.NanXie,KeFeng,BinChen,bMingZhao,Li-PingZhang,Chen-HoTung,Li-ZhuWu,ShiqiPeng,Amodulardesignedcopolymerwithantithromboticactivityandimagingcapability.ChemComm2014,50,9535-9542.IF=6.718
22.FengxiangDu,XiaoyiZhang,ShanLi,YaonanWang,MeiqingZheng,YujiWang,ShuruiZhao,JianhuiWu,LinGui,MingZhao,ShiqiPeng,Mechanismofformingtrimer,self-assemblingnano-particleandinhibitingtumorgrowthofsmallmoleculeCIPPCT,MedChemComm2014,5,1634-1643.IF=2.626
23.WenhuaZhao,YujiWang,WeijiaHao,MingZhao,ShiqiPeng,Invitroinhibitionoffattyacidsynthaseby1,2,3,4,6-penta-O-galloyl-β-D-glucoseplaysavitalroleinanti-tumouractivity.BBRC,2014,445,346-351.IF=2.281
24.NanXie,KeFeng,BinChen,MingZhao,ShiqiPeng,LipingZhang,ChenhoTung,LizhuWu,Water-solublecopolymericmaterials:switchableNIRtwo-photonfluorescenceimagingagentsforlivingcancercells.J.Mater.Chem.B,2014,2,502-510.IF=6.626
25.ShaoyinWei,WenxinYao,WenyuanJi,JiaqiWei,ShiqiPeng,Qualitativeandquantitativeanalysisofanthraquinonesinrhubarbsbyhighperformanceliquidchromatographywithdiodearraydetectorandmassspectrometry.FoodChemdoi.org/10.1016/j.foodchem.2013.04.074.3.334
26.WenjingWang,ChenjieFang,XiaozhuWang,YuxiChen,WeiFeng,ChunhuaYan,MingZhao,ShiqiPeng,Modifyingmesoporoussilicanano-particletoavoidthemetabolicdeactivationof6-mercaptopurineandmethotrexateincombinatorialchemotherapy.Nanoscale2013,5,6249-6253.6.233封面文章
27.HaimeiZhu,YujiWang,MingZhao,JianhuiWu,XiaoyiZhang,GuodongYang,ShiqiPeng,EnergyminimizedcrystalstructuresofP-selectinsbasedonmoleculardynamicssimulation:Leadingtotwoaveragestructurescapableofdesigninganti-thromboticagents.MedChemComm2013,4,1066-1072.2.722
28.HaimeiZhu,YujiWang,YaonanWang,ShuruiZhao,MingZhao,LinGui,WenyunXu,XiangyunAmyChen,YanmingWang,ShiqiPeng,Foldedconformation,cyclicpentamer,nano-structureandPAD4bindingmodeofYW3-56.JPhysChemC2013,117,10070-10078.4.814
29.ShaomingJin,YaonanWang,HaimeiZhu,YujiWang,ShuruiZhao,MingZhao,*JiawangLiu,JianhuiWu,WenGao,andShiqiPeng,*NanosizedAspirin-Arg-Gly-Asp-Val:eliveryofAspirintoThrombusbytheTargetCarrierArg-Gly-Asp-Valetrapeptide.ACSNano,2013,7(9),7664–7673.IF=12.062
30.NanXie,aKeFeng,b,*BinChen,bMingZhao,aShiqiPeng,a,*Li-PingZhang,bChen-HoTung,bandLi-ZhuWub,*,Water-solublecopolymericmaterials:theswitchableNIRtwo-photonfluorescenceimagingagentsforlivingcancercells.JournalofMaterialsChemistryB,DOI:10.1039/c0xx00000x6.101
201240.493
31.YujiWang,JianhuiWu,GuifengKang,MingZhao,*LinGui,NingLi,LiPeng,XiaoyiZhang,LiLiandShiqiPeng*.Novelnano-materials,RGD-tetrapeptide-modified17b-amino-11a-hydroxyandrost-1,4-diene-3-one:synthesis,self-assemblybasednano-imagesandinvivoanti-osteoporosisevaluation†.J.Mater.Chem.,2012,22,4652–46595.968
32.LiLi,MingZhao,*WenhaoLi,YujiWang,ZhugeZhang,RanAnandShiqiPeng*.Self-complexationandcomplexation-controlledtargetcancertherapy†Med.Chem.Commun.2012,3,1059-10612.8
33.GuiLin,ZhaoMing,WangYuji,WangYinye,QinYang,LiLi,ShiqiPeng.Synthesis,nano-features,exvivoanti-plateletaggregationandinvivoantithromboticactivitiesofpoly-α,β-DL-aspartyl-L-arginine.Med.Chem.Commun.,2012,3,102-108.2.8
34.JianhuiWu•LeiWei•MingZhao•YujiWangGuifengKang•ShiqiPeng，N-[2(3-Carboxyl-9-benzyl-carboline-1-yl)ethyl-1-yl]-aminoacids:correlationofspectralpropertywithinvivoanti-tumoractivity,MedChemRes(2012)21:116–1231.271
35.HuiliangZhang,YujiWang,†MingZhao,*JianhuiWu,XiaoyiZhang,LinGui,MeiqingZheng,LiLi,JiawangLiu,andShiqiPeng*.SynthesisandInVivoLeadDetoxificationEvaluationofPoly-α,β-DLaspartyl-L-methionine.Chem.Res.Toxicol.2012,25,471−4773.779
36.YujiWang,aGuifengKang,aJiawangLiu,aMingZhao,*aJianhuiWu,XiaoyiZhang,aYeLi,aXiaoboZhong,bYifanYangaandShiqiPeng*aNovelpotassiumN-[(2S,3R,4R,5R)-2,3,4,5,6-pentahydroxylhex-1-yl]-L-aminoaciddichloroplatinates(II)withhighanti-tumoractivityandlowsidereaction.Metallomics,2012,4,441–4473.902
37.LiLi,PhD,MingZhao,PhD1,WenhaoLi,MS,YujiWang,PhD,ChunnaLiu,MS,ZhugeZhang,BS,SongchunSu,MS,ShiqiPeng,PhD⁎,1pH-Dependentnanostructurebasedonisoquinoline-cyclodextrinconjugateforthrombosistherapy.Nanomedicine:Nanotechnology,Biology,andMedicinexx(2012)xxx–xxx6.692
38.GuifengKang,YujiWang(Co-firstauthor),JiawangLiu,JianhuiWu,MingZhao,GuochunLi,NingLi,LiPeng,XiaoyiZhang,LiLi,NathanMair,ShiqiPeng.Developmentofthree-componentconjugates:Togetnano-globeswithporoussurface,highinvivoanti-osteoporosisactivityandminimalsideeffects.J.Mater.Chem.,2012,22,21740-239.LiLi,JianhuiWu,MingZhao,YujiWang,HuiliangZhang,XiaoyiZhang,LinGui,JiawangLiu,NathanMair,andShiqiPeng,Poly-a,β-DL-Aspartyl-L-Cysteine:ANovelNano-MaterialHavingPorousStructure,SpecialComplexationCapabilityforPb(II)invitroandSelectivityofRemovingPb(II)invivo.Chem.Res.Toxicol.,2012,25,1948-1954.3.779
40.GuodongYang,HaimeiZhu,MingZhao,JianhuiWu,YujiWang,YanjuWang,MeiqingZheng,MinChen,JiawangLiu,ShiqiPeng,Theapplicationoftetrahydroisoquinoline-3-carbonyl-TARGD(F)Fasanti-thromboticagenthavingdualmechanismsofaction.MolecularBioSystems,2012,8,2672-2679.3.534
41.NingLi,GuifengKang,LinGui,*MingZhao,WenjingWang,JianweiZhang,Yan-FengYue,*ShiqiPeng.NovelCu(II)-RGD-octapeptides:Synthesis,coordinationmode,invitroanti-plateletaggregation/invivoanti-thromboticevaluationandcorrelationofsequencewithnano-structure.Nanomed-Nanotechnol.7,4,2011,403–409IF=6.692北医
42.LiuLiu,LeiWei,YifanYang,MingZhao,*XiaoyiZhang,MeiqingZheng,YujiWangandShiqiPeng*,AclassofnovelAA-Trp-Trp-OBzl:synthesis,invitroanti-proliferation,invivoanti-tumoraction,andintercalationmechanism.Med.Chem.Commun.,2011,2,126-1312.8
43.WenjingWang,MingZhao,*YujiWang,JiawangLiu,JianhuiWu,GuifengKangandShiqiPeng*{2-[1-(3-Methoxycarbonylmethyl-1H-indol-2-yl)-1-methyl-ethyl]-1Hindol-3-yl}-aceticacidmethylester(MIAM):Itsanti-cancerefficacyandintercalationmechanismidentifiedviamulti-modelsystemsw.MolecularBioSystems.2011,7,766-7723.534
44.HongWang,LePeng,MingZhao,JiawangLiu,XiaoyiZhang,YujiWang,JianhuiWu,LiLi,ShiqiPeng.2-Substituted(S)-2-(3,3-dimethyl-1-oxo-10,10a-dihydroimidazo[1,5-b]isoquino-lin-2(1H,3H,5H)-yl)aceticacids:Conformationalprediction,synthesis,anti-thromboticandvasodilativeevaluation.Bioorganic&MedicinalChemistryVolume19,Issue2,15January2011,Pages871-8822.921
45.JianhuiWu,MingZhao&ShiqiPeng,Quinazolin-4(3H)-onescapableofupregulatingtheexpressionofendogenousapolipoproteinA-1,ExpertOpin.Ther.Patents2011,21,3431-4353.571
46.YujiWang,XueyunJiang,JiawangLiu,MingZhao,*GuifengKang,JianhuiWu,LiPengandShiqiPeng*,HPLC-MSaidedPC12cellsystems:toquantitativelymonitortheconversionofnitronylnitroxideinbiologicalsystemswithandwithoutNO.Mol.BioSyst.,2011,7,1678–16833.534
47.YanxiaXua,YujiWangb,MingZhaob,BaoguangHoub,LiPengb,MeiqingZhengb,JianhuiWub,ShiqiPeng.LeaddetoxificationactivitiesandADMEThepatotoxicitiesofaclassofnovel5-(1-carbonyl-L-amino-acid)-2,2-dimethyl-[1,3]dithiolane-4-carboxylicacids.Bioorganic&MedicinalChemistryLetters21(2011)1754–17572.554北医
48.YanxiaXu,YujiWang,LingWang,MingZhao,*XiaoyiZhang,XiaominHu,BaoguangHou,LiPeng,MeiqingZheng,JianhuiWu,andShiqiPeng*,LeadDetoxificationActivitiesofaClassofNovelDMSA_AminoAcidConjugates,Chem.Res.Toxicol.2011,24,979–9843.779
49.MeiqingZheng1,YifanYang1,MingZhao1*,XiaoyiZhang1,JianhuiWu1,GongChen2*,LiPeng1,YujiWang1andShiqiPeng1.AClassofNovelN-Isoquinoline-3-carbonyl-L-aminoAcidBenzylesters:Synthesis,Anti-tumorEvaluationand3DQSARAnalysis.EuropeanJournalofMedicinalChemistry46(2011)1672-16813.346
50.KunYao,MingZhao*,XiaoyiZhang,YujiWang,LiLi,MeiqingZheng,ShiqiPeng**,AclassoforalN-[(1S,3S)-1-methyl-1,2,3,4-tetrahydro-b-carboline-3-carbonyl]-N0-(amino-acid-acyl)hydrazine:Discovery,synthesis,invitroanti-plateletaggregation/invivoanti-thromboticevaluationand3DQSARanalysis,EuropeanJournalofMedicinalChemistry46(2011)3237-32493.346
51.XiaoyiZhang,YifanYang,MingZhao**,LiuLiu,MeiqingZheng,YujiWang,JianhuiWu,ShiqiPeng*,AclassofTrp-Trp-AA-OBzl:Synthesis,invitroanti-proliferation/invivoanti-tumorevaluation,intercalation-mechanisminvestigationand3DQSARanalysis,EuropeanJournalofMedicinalChemistry46(2011)3410-34193.346
52.YujiWang,aLeiWei,aMingZhao,*aShenghuiMei,aMeiqingZheng,aYifanYang,aHongWang,aGongChen*bandShiqiPeng*a,Developmentofhighlyeffectivethree-componentcytoprotectiveadjunctsforcisplatincancertreatment:synthesisandinvivoevaluationinS180-bearingmicewz,Metallomics,2011,3,1212-12173.902
53.ShenghuiMei,zJiawangLiu,zMingZhao,*WenjingWang,YujiWang,GuofengWu,MeiqingZhengandShiqiPeng*FromCerius2basedstereoviewtomouseandenzyme:Themodelsystemsfordiscoveryofnovelurokinaseinhibitors,MolecularBioSystems2011,7,2664–26693.534
54.YujiWang,GuifengKang,MingZhao,*JianhuiWu,XiaoyiZhang,YifanYang,JiawangLiuandShiqiPeng*Anewplatinum-complexshowingeasypreparation,promisinganti-tumoractivity,andbetterefficacyanddistributionpropertiesthanoxaliplatin.Mol.BioSyst.,2011,7,3245-32523.534
55.JiawangLiu,YujiWang,YifanYang,XueyunJiang,MingZhao,*WenjingWang,GuofengWu,JianhuiWu,MeiqingZheng,andShiqiPeng*[a]Pyrolo[1,2:4,5]-1,4-dioxopyrazino[1,2:1,6]pyrido[3,4-b]indoles:AGroupofUrokinaseInhibitors,theirSynthesis,andStereochemistry-DependentActivity.ChemMedChem.2011,6,12,2312–23223.3063.151
56.ChunyuLi,XiaoyiZhang,MingZhao**,YujiWang,JianhuiWu,JiawangLiu,MeiqingZheng,ShiqiPeng*AclassofnovelN-(1-methyl-b-carboline-3-carbonyl)-N’-(aminoacid-acyl)-hydrazines:Aromatizationleadeddesign,synthesis,invitroanti-plateletaggregation/invivoanti-thromboticevaluationand3DQSARanalysis.EuropeanJournalofMedicinalChemistry2011,46,11,5598–56083.346
57.JingchengTang,MingZhao∗,YujiWang,GuifengKang,JianhuiWu,MeiqingZheng,ShiqiPeng∗∗.OnesingleHPLC-PDA/(-)ESI-MS/MSanalysistosimultaneouslydetermine30componentsoftheaqueousextractofRabdosiarubescensJournalofChromatographyB,879(2011)2783–27932.888
58.LinGui,MingZhao*,YinyeWang,YangQin,JiangyuanLiu,ShiqiPeng*.Synthesis,nanofeatures,invitrothrombuslysisactivityandinvivothrombolyticactivityofpoly-α,β-aspartyl-L-alanine.Nanomedicine(2010)5(5),703–7146.202
59.JiawangLiu,XueyunJiang,†MingZhao,*XiaoyiZhang,MeiqingZheng,LiPeng,andShiqiPeng*.AClassof3S-2-Aminoacyltetrahydro-β-carboline-3-carboxylicAcids:TheirFacileSynthesis,InhibitionforPlateletActivation,andHighinVivoAnti-ThromboticPotency.J.Med.Chem.2010,53,3106–3116(IF=5.207)
60.JiawangLiu,MingZhao*,KeduoQian,XiaoyiZhang,Kuo-HsiungLee*,JianhuiWu,Yi-NanLiu,ShiqiPeng,*Benzyl1,2,3,5,11,11a-hexahydro-3,3-dimethyl-1-oxo-6H-imidazo[30,40:1,2]pyridin[3,4-b]indole-2-substitutedacetates:One-pot-preparation,anti-tumoractivity,dockingtowardDNAand3DQSARanalysis.Bioorganic&MedicinalChemistry18(2010)1910–1917(IF=2.978)
61.XiaoyiZhang,WeiWang,ShenlingCheng,MingZhao,*MeiqingZheng,HengWeiChang*,JianhuiWu,ShiqiPeng*.2,3-Diaminoacidmodifying3S-tetrahydroisoquinoline-3-carboxylicacids:Leadingtoaclassofnovelagentswithhighlyunfoldedconformation,selectiveinvitroanti-plateletaggregationandpotentinvivoanti-thromboticactivity.Bioorganic&MedicinalChemistry18(2010)1536–1554(IF=2.978)
62.YinjianZhou,MingZhao*,YingtingWu,ChunyuLi,JianhuiWu,MeiqingZheng,LiPeng,ShiqiPeng,*.AclassofnovelSchiff’sbases:Synthesis,therapeuticactionforchronicpain,anti-inflammationand3DQSARanalysis.Bioorganic&MedicinalChemistry18(2010)2165-2172(IF=2.978)
63.MingZhao,YujiWang,CaixiaHuo,JiawangLiu,ChunyuLi,XiaoyiZhang,LiPeng,andShiqiPeng*,LeadDetoxificationActivityandADMETHepatotoxicityofN-(r-LArabino-furanos-1-yl)-L-cysteine.Chem.Res.Toxicol201023（7）(4.148)
64.JianhuiWu,ChunyuLi,MingZhao*,WenjingWang,YujiWang,ShiqiPeng*,Aclassofnovelcarbolineintercalators:Theirsynthesis,invitroanti-proliferation,invivoanti-tumoraction,and3DQSARanalysis,Bioorganic&MedicinalChemistry18(2010)6220–62292.978
65.GuifengKang,MingZhao,XiaoyiZhang,LiPeng,ChunboLi,WeiMao,WeidongYe,ShiqiPeng.AclassofnovelconjugatesofsubstitutedpurineandGly-AA-OBzl:Synthesisandevaluationoforallyanalgesicactivity.Bioorganic&MedicinalChemistryLetters,Volume20,Issue20,15October2010,Pages6157-61602.661
66.FeiHuang,MingZhao*,XiaoyiZhang,ChaoWang,KeduoQian,Jen-YunKuo,SusanMorris-Natschke,Kuo-HsiungLee,ShiqiPeng,Synthesis,DNAIntercalationand3DQSARAnalysisofcis-2,4,5-Trisubstituted-1,3-dithiolanesasaNovelClassofAntitumorAgents.Bioorg.Med.Chem.2009,17,6085–6095(IF=3.075)
67.JianhuiWu,MingZhao*,KeduoQian,Kuo-HsiungLee,SusanMorris-Natschke,ShiqiPeng,NovelN-(3-carboxyl-9-benzylcarboline-1-yl)ethylaminoacids:Synthesis,antitumorevaluation,intercalatingdetermination,3DQSARanalysisanddockinginvestigation.Eur.J.Med.Chem.2009,44,4153–4161(IF=2.882)
68.MingZhao,JiangyuanLiu,XiaoyiZhang,LiPeng,ChunyuLi,ShiqiPeng,3DQSARofnovelestrogen-RGDpeptideconjugates:Gettinginsightintostructuraldependenceofanti-osteo-porosisactivityandsideeffectofestrogeninERT.Bioorg.Med.Chem.2009,17,3680-3689.(IF=3.075)
69.MingZhao,CaixiaHuo,YujiWang,ChongyuLi,XiaoyiZhang,LiPeng,ShiqiPeng,StereoselectivesynthesisofNovelN-(α-L-arabinose-1-yl)-L-aminoAcids.Tetrahedron:Asymmetry,2009,20,247-258.(IF=2.796)
70.JiangyuanLiu,XiaoyiZhang,MingZhao*,ShiqiPeng,Synthesis,Evaluationand3DQSARAnalysisofNovelEstradiol-RGDOctapeptideConjugateswithOralAnti-osteoporosisActivity,Eur.J.Med.Chem.2009,44,1689-1704.(IF=2.882)
71.ShenlingCheng,XiaoyiZhang,WeiWang,MingZhao*,MeiqingZheng,HengWeiChang,JianghuiWu,ShiqiPeng,AClassofNovelN-(3S-1,2,3,4-Tetrahydroisoquinoline-3-carbonyl)-L-aminoAcids:TheirSynthesis,AntithromboticActivityEvaluationand3DQSARAnalysis.Eur.J.Med.Chem.44（2009）,4904-4919(IF=2.882)
72.JinghuaZhao,GuifengKang,WeiWang,MingZhao*,XiaoyiZhang,ChunboLu,WeiMao,HengWeiChang,WeidongYe,ShiqiPeng,N-[2-Chloro-9H-purin-6-yl]-N-cyclopropyl-glycylaminoacidsandderivatives:Synthesis,evaluationasaclassofnovelanalgesicsand3DQSARanalysis.Bioorg.Med.Chem.2009,17,6305-6310.(IF=3.075)
73.MeiqingZheng,XiaoyiZhang,MingZhao*,HengWeiChang,WeiWang,YujiWang,ShiqiPeng,(3S)-N-(L-Aminoacyl)-1,2,3,4-tetrahydroisoquinolines,aClassofNovelAnti-thromboticAgents:Synthesis,Bioassay,3DQSAR,andADMEAnalysis,Bioorg.Med.Chem.2008,16,9574-9587.(IF=3.075)
74.LiLi,GuohuiCui,MingZhao*,YujiWang,HongWang,WeiLi,ShiqiPeng,Assemblyofβ-cyclodextrinwith3S-tetrahydro-β-carboline-3-carboxylicacidandself-assemblyof6-(3S-carboline-3-carboxylaminoethylamino)-6-deoxy-β-cyclodextrin:Approachestoenhanceanti-oxidationstabilityandanti-thromboticpotency.TheJournalofPhysicalChemistryB,2008,112,12139-12147.(IF=4.189)
75.MeiYang,GuohuiCui,MingZhao*,ChaoWang,LiliWang,HuLiuandShiqiPeng,TheeffectofcomplexationofCu(II)withP6Apeptideanditsanalogsontheirthrombolyticactivities,InternationalJournalofPharmaceutics.2008,362,81-87.(IF=3.061)
76.JiawangLiu,MingZhao*,GuohuiCui,XiaoyiZhang,JunWang&ShiqiPeng,Methyl(11as)-1,2,3,5,11,11a-hexahydro-3,3-dimethyl-1-oxo-6H-imidazo[3',4':1,2]pyridin[3,4-b]indol-2-substitutedacetates:Synthesisandthree-dimensionalquantitativestructure-activityrelationshipinvestigationasaclassofnovelvasodilators,J.Med.Chem.2008,51,4715-4723.(IF=4.898)
77.XueRen,GuohuiCui,MingZhao*,ChaoWang,ShiqiPeng,CoordinationofThrombolyticPro-Ala-LyspeptideswithCu(II):Leadingtonano-scaleself-assembly,increaseofthrombolyticactivityandadditionalvasodilation,TheJournalofPhysicalChemistryB,2008,112,8174-8180.(IF=4.189)
78.YujiWang,MingZhao*,GuohuiCui,ChunyingCui,JingfangJu,ShiqiPeng,TherapeuticAlliance:UsingN-(2,3,4,5,6-Pentahydroxylhex-1-yl)-N-dithiocarbamate-L-isoleucineDisodiumtoImprovetheToxicityandSurvivalofCisplatinReceivingMice,TheOpenToxicologyJournal,2008,2,1-6.
79.YuChen,GuohuiCui,MingZhao*,ChaoWang,KeduoQian,SusanMorris-Natschke,Kuo-HsiungLee,ShiqiPeng,Synthesis,nano-scaleassembly,andinvivoanti-thromboticactivityofnovelshortpeptidescontainingL-ArgandL-AsporL-Glu,Bioorg.Med.Chem.2008,16,5914-5925.(IF=3.075)
80.ZhiyuTang,MingZhao*,ChanglingLi,YinyeWang,ShiqiPeng,Polyaspartoyl·L-arginineinhibitsplateletaggregationthroughstimulationofNOreleasefromendothelialcells,EurJPharmacol2008,588,41-46.(IF=2.787)
81.JianweiZhang,MingZhao*,GuohuiCui,ShiqiPeng,Aclassofnovelnitronylnitroxidelabelingbasicandacidicaminoacids:Synthesis,applicationforpreparingESRoptionallylabelingpeptides,andbioactivityinvestigations,Bioorg.Med.Chem.2008,16,4019-4028.(IF=3.075)
82.YuweiWang,GuohuiCui,MingZhao*,JianYang,ChaoWang,RogerW.Giese,andShiqiPeng,Bioassay-directedpurificationofanacidicphospholipaseA2fromAgkistrodonHalysPallasvenom,Toxicon2008,51,1331-1339.(IF=2.460)
83.XiangminLi,MingZhao*,Yu-RongTang,ChaoWang,ZidingZhang,ShiqiPengN-[2-(5,5-Dimethyl-1,3-dioxane-2-yl)ethyl]aminoacids:Theirsynthesis,anti-inflammatoryevaluationandQSARanalysis,Eur.J.Med.Chem.2008,43,8-18.(IF=2.882)
84.LanrongBi,MingZhao*,KeliGu,ChaoWang,JingfangJuc,ShiqiPeng,Towardthedevelop-mentofchemopreventionagents(III):Synthesisandanti-inflammatoryactivitiesofanewclassof5-glycylamino-2-substituted-phenyl-1,3-dioxacycloalkanes,Bioorg.Med.Chem.2008,16,1764-1774.(IF=3.075)
85.MingZhao,ZhengLi,LiPeng,Yu-RongTang,ChaoWang,ZidingZhang,ShiqiPeng,Anewclassofanalgesicagentstowardprostacyclinreceptorinhibition:synthesis,biologicalstudiesandQSARanalysisof1-hydro.xyl-2-substitutedphenyl-4,4,5,5-tetramethylimidazolines,Eur.J.Med.Chem.2008,43,1048-1058.(IF=2.882)
86.MingZhao,XinJia,ChaoWang,QinLi,KexiangZhou,LiliWang,HuLiuandShiqiPeng,PAK:Anessentialmotifforformingβ-turnstructuresandexhibitingthrombolyticeffectforP6Aanditsanalogs,Biochem.CellBiol.,2007,85,730-740.(IF=2.473)
87.JianghuiWu,GuohuiCui,MingZhao*,ChunyingCui,&ShiqiPeng,NovelN-(3-carboxyl-9-benzylcarboline-1-yl)ethylaminoacids:Synthesis,anti-proliferationActivitiesandtwostepcourseofintercalationtowardcalfthymusDNA,MolecularBioSystems,2007,3,855-861.(IF=4.230)
88.JiawangLiu,GuohuiCui,MingZhao*,ChunyingCui,JingfangJu,ShiqiPeng,Dual-actingagentsthatpossessreversingresistanceandanticanceractivities:Design,synthesis,MES-SA/Dx5cellassayandSARof2,2-dimethyl-3-[1’-substi-tutedacetyloxybenzyl]-4-oxoimidazo[3’,5’:2,3]tetrahydro-β-carbolines,Bioorg.Med.Chem.2007,15,7773-7778.(IF=3.075)
89.JiawangLiu,GuofengWu,GuohuiCui,Wei-XuanWang,MingZhao*,ChaoWang,ZidingZhang,ShiqiPeng,Anewclassofanti-thrombosishexahydropyrazino[1’,2’:1,6]-pyrido[3,4-b]indole-1,4-dions:Design,synthesis,logKdeterminationandQSARanalysis,Bioorg.Med.Chem.2007,15,5672-5693.(IF=3.075)
90.MingZhao,ZhengLi,LiPeng,Yu-RongTang,ChaoWang,ZidingZhang,ShiqiPeng,Novel1-oxyl-2-substitutedphenyl-4,4,5,5-tetramethylimidazolines:Synthesis,selectivelyanalgesicactionandQSARanalysis,Bioorg.Med.Chem.2007,15,2815-2826(IF=3.075)
91.KeliGu,LanrongBi,MingZhao*,ChaoWang,JingfangJu,ShiqiPeng,Towardthedevelo-pmentofchemopreventionagents(II):Chemo-enzymaticsynthesisandanti-inflammatoryactivitiesofanewclassof5-amino-2-substitutedphenyl-1,3-dioxacycloalkanes,Bioorg.Med.Chem.2007,15,6273-6290(IF=3.075)
92.YuXiong,MingZhao*,ChaoWang,HengweiChang,ShiqiPeng,ImprovedantiosteoporosispotencyandreducedendometrialmembranehyperplasiaduringHRTwithestrogen-RGDpeptideconjugates,JMed.Chem.2007,50,3340-3353.(IF=4.898)
93.KeliGu,LanrongBi,MingZhao*,ChaoWang,JingfangJu,ShiqiPeng,Towardthedevelopmentofchemopreventionagents(I):Design,synthesisandanti-inflammatoryactivitiesofanewclassof2,5-disubstituted-dioxacycloalkanes,Bioorg.Med.Chem.2007,15,4775-4799(IF=3.075)
94.GuofengWu,LanrongBi,MingZhao*,ChaoWang,MichèleBaudy-Floc’h,JingfangJu,ShiqiPeng,Towardbreastcancerresistanceprotein(BCRP)inhibitors:Design,synthesisofaseriesofnewsimplifiedfumitremorginCanalogues,Tetrahedron,2007,63,5510-5528.(IF=2.796)
95.YujiWang,LanrongBi,BaoguangHou,YuChen,MingZhao*,ChaoWang,WeiWang,JingfangJu,|ShiqiPeng,Designandsynthesisofpentahydroxylhexylaminoacidsandtheireffectonleaddecorporation,Chem.Res.Toxicol.2007,20,609-615.(IF=3.491)
96.MingZhao,ZhengLi,YihuiWu,ChaoWang,ZidingZhang,ShiqiPeng,StudiesonLogP,retentiontimeandQSARof2-substitutedphenylnitronylnitroxidesasfreeradicalscavenger,Eur.J.Med.Chem.2007,42,955-965.(IF=2.882)
97.KeliGu,LanrongBi,MingZhao*,ChaoWang,CherylDolan,MichaelC.Kao,JeffreyB.-H.TokandShiqiPeng,Stereoselectivesynthesisandanti-inflammatoryactivitiesof6-and7-membereddioxacycloalkanes,Bioorg.&Med.Chem.2006,14,1339-1347.(IF=3.075)
98.MingZhao,LanrongBi,WeiBi,ChaoWang,ZheYang,JingfangJuandShiqiPeng,Synthesisofnewclassdipeptideanalogueswithimprovedpermeabilityandantithromboticactivity,Bioorg.&Med.Chem.2006,14,4761-4774.(IF=3.075)
99.YihuiWu,LanrongBi,WeiBi,ZengLi,MingZhao*,ChaoWang,JingfangJu,ShiqiPeng,Novel2-substitutednitronylnitroxidesasfreeradicalscavengers:Synthesis,biologicalevaluationandstructure–activityrelationship,Bioorg.&Med.Chem.2006,14,5711-5720.(IF=3.075)
100.MingZhao,LanrongBi,WeiWang,ChaoWang,MichèleBaudy-Floc’h,JingfangJu,ShiqiPeng,Synthesisandcytotoxicactivitiesofβ-carbolineaminoacidesterconjugates,Bioorg.&Med.Chem.2006,14,6998-7010.(IF=3.075)
1748.5.968
京公网安备 11010802027423号